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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, Alfredo | RP | Scranton WB RailRiders | 28 | 05/26/1997 | New Milford | USA | Left | Left | 5' 10" | 180 lbs | $740,000 |
| Salazar, Hisham | C | Norfolk Tides | 28 | 02/16/1997 | Nevada | USA | Switch | Right | 5' 10" | 185 lbs | $1,300,000 |
| Salinas, Gabriel | SS | Lehigh Valley IronPigs | 25 | 03/09/2000 | Santiago | CRC | Left | Right | 6' 0" | 195 lbs | $2,400,000 |
| Salsa, Estaçio | SP | Toledo Mud Hens | 21 | 11/23/2003 | Ejido | VEN | Right | Right | 6' 4" | 205 lbs | - |
| Salzman, Korey | RF | St. Paul Saints | 24 | 02/12/2001 | Encantada-Ranchito El Calaboz | USA | Left | Left | 6' 2" | 200 lbs | $3,200,000 |
| Sambrano, Dave | RF | Columbus Clippers | 27 | 01/18/1998 | San Cristóbal | DOM | Right | Left | 5' 10" | 195 lbs | $1,400,000 |
| Sanchez, Alberto | SP | Scranton WB RailRiders | 23 | 10/22/2001 | Santo Domingo | DOM | Left | Left | 6' 1" | 200 lbs | - |
| Sanchez, Alex | 1B | Toledo Mud Hens | 26 | 03/14/1999 | Santo Domingo | DOM | Left | Left | 6' 1" | 200 lbs | $2,200,000 |
| Sanchez, Leo | 2B | Rochester Red Wings | 25 | 06/15/2000 | Chambas | CUB | Right | Right | 6' 2" | 200 lbs | $3,600,000 |
| Sanchez, Manny | CF | Memphis Redbirds | 22 | 06/11/2003 | Arroyo | PUR | Left | Right | 6' 1" | 190 lbs | - |
| Sanchez, Ruben | SP | Buffalo Bisons | 23 | 09/25/2001 | Paraíso | DOM | Right | Left | 6' 2" | 200 lbs | - |
| Sanders, Josiah | RP | Memphis Redbirds | 29 | 01/29/1996 | Crossett | USA | Right | Right | 6' 4" | 210 lbs | - |
| Sandoval, Alex | LF | Buffalo Bisons | 28 | 05/03/1997 | Cotuí | DOM | Right | Right | 6' 1" | 210 lbs | $1,300,000 |
| Sanford, Greg | RF | Omaha Storm Chasers | 25 | 09/27/1999 | Brownsville | USA | Left | Left | 6' 3" | 215 lbs | - |
| Sarmiento, Josh | C | Durham Bulls | 25 | 10/03/1999 | Crowley | USA | Right | Right | 6' 1" | 215 lbs | $5,500,000 |
| Schaefer, Chris | SP | Gwinnett Stripers | 26 | 09/16/1998 | Erie | USA | Right | Right | 5' 9" | 175 lbs | $1,200,000 |
| Schaefer, Ryan | RP | Charlotte Knights | 23 | 02/14/2002 | Greenfield | USA | Left | Right | 6' 4" | 210 lbs | - |
| Schaffert, Adam | C | Memphis Redbirds | 26 | 04/14/1999 | Rochester | USA | Right | Right | 5' 10" | 190 lbs | $3,600,000 |
| Schamerhorn, Chris | SP | Lehigh Valley IronPigs | 24 | 06/11/2001 | Village Park | USA | Right | Right | 6' 2" | 200 lbs | $4,000,000 |
| Scheid, B.J. | RP | Free Agent | 29 | 08/14/1996 | Memphis | USA | Right | Right | 5' 10" | 185 lbs | - |
| Schmidt, Jordan | RP | Free Agent | 19 | 07/06/2006 | Tuscaloosa | USA | Right | Right | 5' 10" | 165 lbs | - |
| Schow, Nate | SS | Iowa Cubs | 26 | 07/13/1999 | Gardner | USA | Right | Right | 6' 1" | 200 lbs | $4,600,000 |
| Schubert, Franklin | SS | Buffalo Bisons | 27 | 04/27/1998 | Wilton | USA | Right | Right | 6' 2" | 195 lbs | $4,200,000 |
| Schultz, Rob | RP | Gwinnett Stripers | 25 | 03/16/2000 | Fort Wayne | USA | Right | Right | 5' 11" | 195 lbs | - |
| Seifert, Zach | SP | Worcester Red Sox | 21 | 10/24/2003 | Folcroft | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sellers, Pat | RF | Columbus Clippers | 27 | 08/15/1998 | Irvine | USA | Left | Left | 6' 1" | 200 lbs | - |
| Shekhtman, Jonathan | RP | Lehigh Valley IronPigs | 24 | 08/17/2001 | Leavenworth | USA | Right | Right | 6' 1" | 200 lbs | $2,800,000 |
| Shepard, Jerry | CL | Iowa Cubs | 22 | 03/31/2003 | Roxbury | USA | Right | Right | 6' 1" | 185 lbs | $740,000 |
| Sheppard, Quintin | 1B | Buffalo Bisons | 28 | 05/03/1997 | Melbourne | AUS | Left | Left | 6' 3" | 210 lbs | $920,000 |
| Sherman, Chad | RP | Free Agent | 22 | 06/26/2003 | West Plains | USA | Right | Right | 5' 10" | 180 lbs | - |
| Sherrard, Adam | RP | Indianapolis Indians | 28 | 07/03/1997 | Ocean Township | USA | Left | Left | 6' 2" | 200 lbs | - |
| Shock, Dustin | RP | Free Agent | 23 | 12/05/2001 | Ashton-Sandy Spring | USA | Right | Right | 6' 1" | 200 lbs | - |
| Shook, Joel | RP | Free Agent | 29 | 07/09/1996 | Arcadia | USA | Right | Right | 6' 1" | 200 lbs | - |
| Short, Josh | SS | Louisville Bats | 29 | 04/15/1996 | Azusa | USA | Right | Right | 6' 0" | 185 lbs | - |
| Shubert, Andy | RP | Memphis Redbirds | 22 | 10/04/2002 | Columbia | USA | Left | Right | 6' 4" | 205 lbs | - |
| Silas, Harry | RP | Free Agent | 24 | 02/08/2001 | Arlington Heights | USA | Right | Right | 5' 10" | 180 lbs | - |
| Simard, Jeremy | C | Omaha Storm Chasers | 27 | 06/18/1998 | Hazlehurst | USA | Right | Right | 6' 2" | 215 lbs | $740,000 |
| Simpson, Sonny | SP | St. Paul Saints | 22 | 11/02/2002 | Lawrence | USA | Switch | Right | 5' 11" | 180 lbs | - |
| Skinner, Mike | LF | Charlotte Knights | 21 | 10/14/2003 | Edgewood | USA | Left | Left | 6' 1" | 195 lbs | - |
| Slaughter, Josh | 2B | Scranton WB RailRiders | 26 | 06/04/1999 | Irondequoit | USA | Right | Right | 6' 0" | 185 lbs | $4,400,000 |
| Smith, David | CF | Jacksonville Jumbo Shrimp | 23 | 05/21/2002 | West Valley City | USA | Right | Right | 6' 0" | 180 lbs | - |
| Smith, Malachi | C | Norfolk Tides | 28 | 07/30/1997 | Pahrump | USA | Right | Right | 6' 0" | 210 lbs | $770,000 |
| Smith, Mark | CL | Charlotte Knights | 22 | 03/27/2003 | Lowell | USA | Right | Right | 6' 0" | 190 lbs | - |
| Smith, Nick | RF | Memphis Redbirds | 25 | 07/01/2000 | Huntingburg | USA | Right | Right | 6' 1" | 210 lbs | $1,400,000 |
| Smith, Pat | SS | Columbus Clippers | 22 | 03/10/2003 | West Palm Beach | USA | Right | Right | 6' 1" | 185 lbs | - |
| Smith, Robert | LF | Scranton WB RailRiders | 26 | 10/17/1998 | Wauzeka | USA | Right | Right | 5' 11" | 190 lbs | $4,800,000 |
| Smyczynski, Mark | RP | Columbus Clippers | 24 | 03/03/2001 | Randolph | USA | Right | Right | 6' 2" | 200 lbs | - |
| Soberano, Luis | 2B | Charlotte Knights | 25 | 11/16/1999 | Santo Domingo | DOM | Right | Right | 6' 2" | 195 lbs | $4,000,000 |
| Solano, Antonio | C | Durham Bulls | 26 | 10/19/1998 | Maracay | VEN | Right | Right | 6' 0" | 210 lbs | - |
| Sonnier, Mark | RP | St. Paul Saints | 27 | 02/19/1998 | Dubuque | USA | Left | Right | 6' 1" | 205 lbs | $1,820,000 |
| Sorensen, Shane | SP | Louisville Bats | 19 | 08/05/2006 | Evansville | USA | Right | Right | 6' 0" | 175 lbs | - |
| Sorrells, Steve | 1B | Memphis Redbirds | 23 | 11/02/2001 | Silverton | USA | Right | Right | 6' 1" | 205 lbs | $1,600,000 |
| Soto, Roberto | SP | Syracuse Mets | 24 | 11/02/2000 | San Juan | PUR | Left | Left | 6' 0" | 200 lbs | - |
| Spack, Lee | RP | St. Paul Saints | 29 | 03/29/1996 | Peekskill | USA | Left | Right | 6' 0" | 200 lbs | - |
| Spry, Ryan | RP | Rochester Red Wings | 28 | 05/17/1997 | Berkeley | USA | Right | Right | 5' 10" | 185 lbs | - |
| Starr, Jason | LF | Durham Bulls | 24 | 12/30/2000 | Ventura | USA | Right | Right | 6' 0" | 205 lbs | $2,800,000 |
| Statham, Craig | SP | Buffalo Bisons | 29 | 04/23/1996 | Arlington | USA | Left | Right | 5' 11" | 190 lbs | - |
| Stevens, Kyle | 1B | Charlotte Knights | 29 | 06/11/1996 | Lauderhill | USA | Right | Right | 6' 2" | 200 lbs | $740,000 |
| Stober, Jon | CF | Lehigh Valley IronPigs | 22 | 07/03/2003 | Arcadia | USA | Right | Right | 6' 2" | 195 lbs | $740,000 |
| Stocking, Justin | CL | Louisville Bats | 24 | 09/17/2000 | Houston | USA | Left | Left | 6' 0" | 195 lbs | $3,800,000 |
| Strickhouser, Billy | SP | Louisville Bats | 25 | 06/04/2000 | Beaverdam Lake-Salisbury Mills | USA | Right | Right | 6' 2" | 210 lbs | $740,000 |
| Sullivan, Billy | SP | Free Agent | 27 | 07/02/1998 | Milwaukee | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sullivan, Justin | RP | Free Agent | 27 | 06/11/1998 | Moodus | USA | Right | Right | 6' 4" | 220 lbs | - |
| Summers, Bryan | 3B | Buffalo Bisons | 23 | 12/12/2001 | Walla Walla | USA | Right | Right | 6' 2" | 205 lbs | $3,200,000 |
| Sutter, Matt | LF | Free Agent | 29 | 02/16/1996 | Houston | USA | Right | Right | 6' 1" | 205 lbs | - |
| Swann, Brent | RP | Louisville Bats | 23 | 01/17/2002 | Portsmouth | USA | Right | Right | 6' 3" | 205 lbs | - |
| Swanson, Ben | 3B | Nashville Sounds | 22 | 05/23/2003 | Bellaire | USA | Right | Right | 6' 0" | 180 lbs | - |
| Swerdlow, Tim | RF | Buffalo Bisons | 31 | 11/14/1993 | Halifax | CAN | Right | Right | 6' 6" | 250 lbs | $4,200,000 |
| Swiger, Matt | C | Indianapolis Indians | 26 | 11/20/1998 | Carol City | USA | Right | Right | 5' 11" | 200 lbs | - |
