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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, Alfredo | RP | Scranton WB RailRiders | 28 | 05/26/1997 | New Milford | USA | Left | Left | 5' 10" | 180 lbs | $740,000 |
| Salazar, Hisham | C | Norfolk Tides | 28 | 02/16/1997 | Nevada | USA | Switch | Right | 5' 10" | 185 lbs | $1,300,000 |
| Salazar, Rene | SP | Syracuse Mets | 26 | 10/01/1998 | San Cristóbal | DOM | Right | Right | 6' 0" | 195 lbs | - |
| Salcido, Hector | RP | Gwinnett Stripers | 26 | 11/24/1998 | Santo Domingo | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Salinas, Gabriel | SS | Lehigh Valley IronPigs | 25 | 03/09/2000 | Santiago | CRC | Left | Right | 6' 0" | 200 lbs | $2,400,000 |
| Salsa, Estaçio | SP | Toledo Mud Hens | 21 | 11/23/2003 | Ejido | VEN | Right | Right | 6' 4" | 205 lbs | - |
| Salzman, Korey | RF | St. Paul Saints | 24 | 02/12/2001 | Encantada-Ranchito El Calaboz | USA | Left | Left | 6' 2" | 200 lbs | $3,200,000 |
| Sanchez, Andres | CF | Syracuse Mets | 22 | 02/03/2003 | Santa Bárbara del Zulia | VEN | Right | Right | 6' 2" | 190 lbs | $740,000 |
| Sanchez, Leo | 2B | Rochester Red Wings | 25 | 06/15/2000 | Chambas | CUB | Right | Right | 6' 2" | 200 lbs | $3,600,000 |
| Sanchez, Manny | LF | Memphis Redbirds | 22 | 06/11/2003 | Arroyo | PUR | Left | Right | 6' 1" | 190 lbs | - |
| Sanchez, Miguel | LF | Omaha Storm Chasers | 25 | 06/03/2000 | Santo Domingo | DOM | Right | Right | 6' 1" | 205 lbs | - |
| Sanchez, Ruben | SP | Buffalo Bisons | 23 | 09/25/2001 | Paraíso | DOM | Right | Left | 6' 2" | 200 lbs | - |
| Sanders, Josiah | RP | Memphis Redbirds | 29 | 01/29/1996 | Crossett | USA | Right | Right | 6' 4" | 210 lbs | - |
| Sandoval, Alex | RF | Buffalo Bisons | 28 | 05/03/1997 | Cotuí | DOM | Right | Right | 6' 1" | 210 lbs | $1,300,000 |
| Sandoval, Juan | C | Toledo Mud Hens | 24 | 03/16/2001 | Santo Domingo | DOM | Right | Right | 6' 2" | 220 lbs | $1,700,000 |
| Sanford, Greg | 1B | Omaha Storm Chasers | 25 | 09/27/1999 | Brownsville | USA | Left | Left | 6' 3" | 215 lbs | - |
| Schaefer, Chris | SP | Gwinnett Stripers | 26 | 09/16/1998 | Erie | USA | Right | Right | 5' 9" | 175 lbs | $1,200,000 |
| Schaffert, Adam | C | Memphis Redbirds | 26 | 04/14/1999 | Rochester | USA | Right | Right | 5' 10" | 190 lbs | $3,600,000 |
| Schamerhorn, Chris | RP | Lehigh Valley IronPigs | 24 | 06/11/2001 | Village Park | USA | Right | Right | 6' 2" | 200 lbs | $4,000,000 |
| Scheid, B.J. | RP | Free Agent | 28 | 08/14/1996 | Memphis | USA | Right | Right | 5' 10" | 185 lbs | - |
| Schmidt, Jordan | RP | Free Agent | 18 | 07/06/2006 | Tuscaloosa | USA | Right | Right | 5' 10" | 165 lbs | - |
| Schubert, Franklin | SS | Buffalo Bisons | 27 | 04/27/1998 | Wilton | USA | Right | Right | 6' 2" | 195 lbs | $4,200,000 |
| Schultz, Rob | RP | Gwinnett Stripers | 25 | 03/16/2000 | Fort Wayne | USA | Right | Right | 5' 11" | 195 lbs | - |
| Schwartz, Joe | RP | Nashville Sounds | 27 | 11/21/1997 | Opportunity | USA | Left | Left | 5' 11" | 190 lbs | $790,000 |
| Scott, Sam | LF | Jacksonville Jumbo Shrimp | 27 | 02/11/1998 | Ramapo | USA | Switch | Right | 6' 0" | 190 lbs | $1,400,000 |
| Sellers, Pat | RF | Columbus Clippers | 26 | 08/15/1998 | Irvine | USA | Left | Left | 6' 1" | 200 lbs | - |
| Seubert, Kyle | RF | Louisville Bats | 29 | 06/28/1996 | Mobile | USA | Right | Right | 6' 3" | 225 lbs | $900,000 |
| Shepard, Jerry | CL | Iowa Cubs | 22 | 03/31/2003 | Roxbury | USA | Right | Right | 6' 1" | 185 lbs | $740,000 |
| Sheppard, Quintin | 1B | Buffalo Bisons | 28 | 05/03/1997 | Melbourne | AUS | Left | Left | 6' 3" | 210 lbs | $920,000 |
| Sherman, Chad | RP | Free Agent | 22 | 06/26/2003 | West Plains | USA | Right | Right | 5' 10" | 175 lbs | - |
| Sherrard, Adam | RP | Indianapolis Indians | 27 | 07/03/1997 | Ocean Township | USA | Left | Left | 6' 2" | 200 lbs | - |
| Shock, Dustin | RP | Free Agent | 23 | 12/05/2001 | Ashton-Sandy Spring | USA | Right | Right | 6' 1" | 200 lbs | - |
| Shook, Joel | RP | Free Agent | 28 | 07/09/1996 | Arcadia | USA | Right | Right | 6' 1" | 200 lbs | - |
| Short, Josh | SS | Louisville Bats | 29 | 04/15/1996 | Azusa | USA | Right | Right | 6' 0" | 185 lbs | - |
| Shubert, Andy | RP | Memphis Redbirds | 22 | 10/04/2002 | Columbia | USA | Left | Right | 6' 4" | 205 lbs | - |
| Silas, Harry | RP | Free Agent | 24 | 02/08/2001 | Arlington Heights | USA | Right | Right | 5' 10" | 180 lbs | - |
| Simard, Jeremy | C | Omaha Storm Chasers | 27 | 06/18/1998 | Hazlehurst | USA | Right | Right | 6' 2" | 215 lbs | $740,000 |
| Simpson, Sonny | SP | St. Paul Saints | 22 | 11/02/2002 | Lawrence | USA | Switch | Right | 5' 11" | 180 lbs | - |
| Skinner, Mike | CF | Charlotte Knights | 21 | 10/14/2003 | Edgewood | USA | Left | Left | 6' 1" | 195 lbs | - |
| Slaughter, Josh | 2B | Scranton WB RailRiders | 26 | 06/04/1999 | Irondequoit | USA | Right | Right | 6' 0" | 185 lbs | $4,400,000 |
| Smith, Ben | LF | Charlotte Knights | 25 | 02/08/2000 | Cypress | USA | Switch | Right | 5' 10" | 185 lbs | $1,400,000 |
| Smith, David | CF | Jacksonville Jumbo Shrimp | 23 | 05/21/2002 | West Valley City | USA | Right | Right | 6' 0" | 180 lbs | - |
| Smith, Malachi | C | Norfolk Tides | 27 | 07/30/1997 | Pahrump | USA | Right | Right | 6' 0" | 210 lbs | $770,000 |
| Smith, Mark | CL | Charlotte Knights | 22 | 03/27/2003 | Lowell | USA | Right | Right | 6' 0" | 190 lbs | - |
| Smith, Robert | LF | Scranton WB RailRiders | 26 | 10/17/1998 | Wauzeka | USA | Right | Right | 5' 11" | 190 lbs | $4,800,000 |
| Smyczynski, Mark | RP | Columbus Clippers | 24 | 03/03/2001 | Randolph | USA | Right | Right | 6' 2" | 200 lbs | - |
| Snowden, Bill | 3B | Iowa Cubs | 26 | 05/14/1999 | Hicksville | USA | Right | Right | 6' 0" | 205 lbs | $4,000,000 |
| Solano, Antonio | C | Durham Bulls | 26 | 10/19/1998 | Maracay | VEN | Right | Right | 6' 0" | 210 lbs | - |
| Soto, Roberto | SP | Syracuse Mets | 24 | 11/02/2000 | San Juan | PUR | Left | Left | 6' 0" | 200 lbs | - |
| Stachowiak, Matt | SP | Rochester Red Wings | 23 | 06/08/2002 | Lake of the Woods | USA | Right | Right | 6' 0" | 185 lbs | - |
| Starr, Jason | 1B | Durham Bulls | 24 | 12/30/2000 | Ventura | USA | Right | Right | 6' 0" | 205 lbs | $2,800,000 |
| Statham, Craig | SP | Buffalo Bisons | 29 | 04/23/1996 | Arlington | USA | Left | Right | 5' 11" | 185 lbs | - |
| Stevens, Kyle | 1B | Charlotte Knights | 29 | 06/11/1996 | Lauderhill | USA | Right | Right | 6' 2" | 200 lbs | $740,000 |
| Stober, Jon | CF | Lehigh Valley IronPigs | 21 | 07/03/2003 | Arcadia | USA | Right | Right | 6' 2" | 195 lbs | $740,000 |
| Stoffel, Mike | CF | Jacksonville Jumbo Shrimp | 22 | 08/17/2002 | Paulsboro | USA | Left | Left | 6' 0" | 185 lbs | $740,000 |
| Stoll, Jared | 1B | Scranton WB RailRiders | 23 | 08/30/2001 | Los Angeles | USA | Right | Right | 6' 2" | 235 lbs | $1,300,000 |
| Stueber, Bill | RF | Worcester Red Sox | 23 | 10/16/2001 | Axis | USA | Right | Right | 6' 4" | 205 lbs | - |
| Sullivan, Billy | SP | Free Agent | 26 | 07/02/1998 | Milwaukee | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sullivan, Justin | RP | Free Agent | 27 | 06/11/1998 | Moodus | USA | Right | Right | 6' 4" | 220 lbs | - |
| Summers, Bryan | 3B | Buffalo Bisons | 23 | 12/12/2001 | Walla Walla | USA | Right | Right | 6' 2" | 205 lbs | $3,200,000 |
| Sutter, Matt | LF | Free Agent | 29 | 02/16/1996 | Houston | USA | Right | Right | 6' 1" | 205 lbs | - |
| Swann, Brent | RP | Louisville Bats | 23 | 01/17/2002 | Portsmouth | USA | Right | Right | 6' 3" | 210 lbs | - |
| Swanson, Ben | 3B | Nashville Sounds | 22 | 05/23/2003 | Bellaire | USA | Right | Right | 6' 0" | 175 lbs | - |
| Sweatt, Scott | RP | Charlotte Knights | 26 | 05/20/1999 | New York | USA | Left | Left | 6' 1" | 200 lbs | - |
| Swiger, Matt | C | Indianapolis Indians | 26 | 11/20/1998 | Carol City | USA | Right | Right | 5' 11" | 200 lbs | - |
| Sylvester, George | RP | Iowa Cubs | 24 | 11/01/2000 | Dyersburg | USA | Right | Right | 6' 0" | 195 lbs | - |
| Symons, Brad | 3B | Scranton WB RailRiders | 26 | 08/29/1998 | Oswego | USA | Right | Right | 6' 0" | 205 lbs | $1,520,000 |
