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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| O'Neil, Pat | 2B | Charlotte Knights | 24 | 03/21/2002 | Syracuse | USA | Right | Right | 6' 1" | 210 lbs | - |
| O'Reilly, Don | SP | Scranton WB RailRiders | 25 | 03/31/2000 | Thetford Mines | CAN | Right | Right | 6' 0" | 200 lbs | $2,200,000 |
| Ocasio, Oscar | SP | Free Agent | 25 | 05/06/2000 | Barcelona | VEN | Left | Left | 6' 2" | 205 lbs | - |
| Odom, Dale | 2B | Free Agent | 24 | 04/22/2001 | Franklin Lakes | USA | Right | Right | 6' 1" | 200 lbs | - |
| Ogle, Mike | RP | Rochester Red Wings | 24 | 10/21/2001 | Jackson | USA | Right | Right | 6' 1" | 210 lbs | $2,920,000 |
| Oles, Chris | CF | Rochester Red Wings | 25 | 03/26/2001 | McCall | USA | Switch | Right | 6' 1" | 195 lbs | $2,000,000 |
| Olivera, Francisco | RP | Columbus Clippers | 23 | 04/11/2002 | Woodmore | USA | Left | Left | 5' 9" | 180 lbs | - |
| Ontiveros, Oscar | 2B | Lehigh Valley IronPigs | 18 | 05/20/2007 | Cary | USA | Right | Right | 6' 0" | 180 lbs | - |
| Ornelas, Raul | RP | Free Agent | 22 | 08/11/2003 | Monroe | USA | Left | Left | 6' 2" | 185 lbs | - |
| Orpilla, Karl-Anthony | SP | Free Agent | 26 | 10/13/1999 | Delaware | USA | Right | Right | 6' 3" | 205 lbs | - |
| Orrostieta, Bill | 3B | Nashville Sounds | 26 | 12/31/1999 | MaiquetÃa | VEN | Right | Right | 6' 1" | 205 lbs | $740,000 |
| Ortega, Dave | SP | Columbus Clippers | 18 | 10/17/2007 | Berea | USA | Right | Right | 6' 2" | 180 lbs | - |
| Ortiz, Hector | SP | Durham Bulls | 24 | 11/17/2001 | Naranjito | PUR | Left | Left | 6' 2" | 195 lbs | - |
| Ortiz, Joaquin | SP | Free Agent | 29 | 02/11/1997 | Araure | VEN | Left | Left | 6' 1" | 200 lbs | - |
| Ortiz, Raul | 3B | Durham Bulls | 25 | 08/14/2000 | Machiques | VEN | Right | Right | 6' 2" | 210 lbs | $5,800,000 |
| Ospina, John | LF | Louisville Bats | 26 | 09/06/1999 | Commack | USA | Right | Right | 5' 10" | 185 lbs | - |
| Osuna, Juan | RP | Free Agent | 25 | 10/09/2000 | Puerto la Cruz | VEN | Left | Left | 6' 1" | 200 lbs | - |
| Otero, Rich | RP | Worcester Red Sox | 25 | 12/10/2000 | Phoenix | USA | Left | Left | 6' 0" | 200 lbs | $3,400,000 |
| Otis, DeAndre | RP | Iowa Cubs | 24 | 10/10/2001 | Santee | USA | Right | Right | 5' 11" | 200 lbs | - |
| Owens, Bill | CF | Louisville Bats | 20 | 01/04/2006 | Toledo | USA | Right | Right | 6' 3" | 190 lbs | - |
| Owusu, Mike | C | Free Agent | 29 | 04/28/1996 | San Diego | USA | Right | Right | 6' 4" | 220 lbs | - |
