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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saco, Jose | 2B | Dunedin Blue Jays | 20 | 12/05/2005 | Santo Domingo | DOM | Right | Right | 6' 0" | 175 lbs | - |
| Salway, Dave | 2B | Fort Myers Mighty Mussels | 19 | 03/11/2006 | Woodmere | USA | Left | Right | 5' 10" | 160 lbs | - |
| Sanchez, Alex | RF | Tampa Tarpons | 20 | 09/19/2005 | Caucagüita | VEN | Right | Right | 6' 2" | 185 lbs | - |
| Sanchez, Johnny | RP | Free Agent | 26 | 11/20/1999 | Santiago | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Sandler, Nick | LF | Palm Beach Cardinals | 22 | 02/25/2003 | Cleveland | USA | Right | Right | 6' 2" | 190 lbs | - |
| Santana, Juan | C | Clearwater Threshers | 22 | 12/25/2002 | Trujillo Alto | PUR | Right | Right | 6' 1" | 210 lbs | - |
| Scott, David | SP | Bradenton Marauders | 23 | 09/27/2002 | Pharr | USA | Right | Right | 6' 4" | 205 lbs | - |
| Seda, Manny | 3B | Bradenton Marauders | 24 | 03/17/2001 | Villa Riva | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Serrano, Leo | SP | St. Lucie Mets | 21 | 08/11/2004 | El Monte | USA | Right | Right | 6' 2" | 190 lbs | - |
| Seto, Yu-wei | SP | Clearwater Threshers | 18 | 11/19/2007 | Sydney | AUS | Left | Left | 6' 1" | 180 lbs | - |
| Sheridan, Jeff | RP | Jupiter Hammerheads | 19 | 06/29/2006 | Wilna | USA | Right | Left | 5' 10" | 170 lbs | - |
| Shropshire, Matt | SP | Daytona Tortugas | 23 | 06/06/2002 | Brookhaven | USA | Right | Right | 6' 4" | 205 lbs | - |
| Sifuentes, Angel | 1B | Dunedin Blue Jays | 22 | 03/10/2003 | El Seibo | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Smith, Bobby | SP | Bradenton Marauders | 21 | 09/20/2004 | Memphis | USA | Right | Right | 6' 0" | 185 lbs | - |
| Smith, Freddy | LF | Dunedin Blue Jays | 21 | 06/09/2004 | White Plains | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sommerfeldt, Roger | RP | St. Lucie Mets | 24 | 03/31/2001 | Islandia | USA | Left | Left | 5' 9" | 180 lbs | - |
| Sotelo, Jordan | 2B | St. Lucie Mets | 23 | 01/20/2002 | Baníca | DOM | Right | Right | 6' 1" | 185 lbs | - |
| Soto, Alberto | 1B | Lakeland Flying Tigers | 23 | 11/16/2002 | Cumberland | USA | Left | Right | 5' 9" | 175 lbs | - |
| St. Germain, Jason | RP | Palm Beach Cardinals | 22 | 04/26/2003 | Nottingham | USA | Left | Left | 6' 1" | 190 lbs | - |
| Starcher, Kyle | LF | Tampa Tarpons | 23 | 02/03/2002 | Plainfield | USA | Switch | Left | 6' 1" | 205 lbs | - |
| Statham, Kelly | C | Dunedin Blue Jays | 23 | 02/08/2002 | Passaic | USA | Right | Right | 6' 0" | 200 lbs | - |
| Steinhilber, Gordie | CL | Daytona Tortugas | 22 | 02/19/2003 | Long Lake | USA | Right | Right | 5' 11" | 185 lbs | - |
| Stives, Kevin | SP | Bradenton Marauders | 22 | 07/11/2003 | Lodi | USA | Left | Right | 6' 0" | 185 lbs | - |
| Stuker, Matt | CL | Dunedin Blue Jays | 24 | 11/19/2001 | El Monte | USA | Left | Left | 6' 3" | 205 lbs | - |
