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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sanchez, Jose | SP | Hillsboro Hops | 23 | 01/26/2002 | Seven Trees | USA | Right | Right | 6' 2" | 195 lbs | - |
| Sanchez, Willie | RP | Free Agent | 18 | 09/17/2006 | Boca Chica | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Sanford, Eric | 1B | Eugene Emeralds | 23 | 12/09/2001 | Milwaukee | USA | Right | Right | 6' 0" | 200 lbs | - |
| Santos, Alberto | LF | Everett AquaSox | 23 | 11/06/2001 | Jacksonville | USA | Switch | Left | 6' 1" | 195 lbs | $1,800,000 |
| Scott, Ben | 3B | Everett AquaSox | 20 | 10/27/2004 | Great Falls | USA | Switch | Right | 6' 3" | 190 lbs | - |
| Scott, Devin | 3B | Eugene Emeralds | 22 | 01/18/2003 | Germantown | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Scudder, Ian | 2B | Spokane Indians | 24 | 05/10/2001 | Seabrook | USA | Right | Right | 6' 0" | 190 lbs | $2,400,000 |
| Sebuggwawo, Salah | SP | Tri-City Dust Devils | 21 | 07/16/2003 | Dakar | SEN | Right | Right | 5' 9" | 165 lbs | - |
| Sharkey, Kevin | RF | Spokane Indians | 21 | 11/22/2003 | New Orleans | USA | Right | Right | 5' 10" | 175 lbs | - |
| Shaw, Ed | SS | Free Agent | 24 | 11/09/2000 | Amherst | USA | Right | Right | 6' 1" | 200 lbs | - |
| Shaw, Scott | RP | Hillsboro Hops | 22 | 09/27/2002 | Metairie | USA | Left | Left | 6' 0" | 195 lbs | - |
| Shelton, Pete | 1B | Tri-City Dust Devils | 22 | 09/03/2002 | Willimantic | USA | Left | Left | 6' 1" | 210 lbs | - |
| Shroyer, Mike | RP | Everett AquaSox | 25 | 05/23/2000 | Woodstock | USA | Right | Right | 5' 10" | 190 lbs | - |
| Shuster, J.D. | 1B | Eugene Emeralds | 23 | 07/04/2001 | Spring Valley | USA | Switch | Right | 6' 0" | 210 lbs | - |
| Soldevilla, Bobby | RP | Hillsboro Hops | 24 | 03/11/2001 | Maracaibo | VEN | Right | Right | 6' 0" | 190 lbs | - |
| Solis, Manny | RP | Free Agent | 25 | 04/16/2000 | Los Angeles | USA | Right | Right | 6' 1" | 200 lbs | - |
| Soto, Manny | 2B | Vancouver Canadians | 20 | 09/03/2004 | Santo Domingo | DOM | Right | Right | 6' 0" | 180 lbs | - |
| Stafford, Jeremy | CF | Spokane Indians | 20 | 09/19/2004 | Fort Worth | USA | Left | Left | 6' 1" | 180 lbs | - |
| Stead, Howard | LF | Free Agent | 24 | 11/08/2000 | Thornton-Cleveleys | ENG | Right | Right | 6' 0" | 205 lbs | - |
| Stephens, Rick | LF | Hillsboro Hops | 21 | 09/22/2003 | Amherst | USA | Left | Left | 6' 0" | 200 lbs | - |
| Strickland, Mike | 2B | Free Agent | 24 | 01/03/2001 | Hutchinson | USA | Right | Right | 6' 0" | 190 lbs | - |
| Suarez, Ivan | RP | Free Agent | 24 | 08/09/2000 | Havana | CUB | Left | Right | 6' 3" | 215 lbs | - |
| Sullivan, Mark | 3B | Free Agent | 27 | 06/08/1998 | Kansas City | USA | Right | Right | 6' 1" | 205 lbs | - |
