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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saidana, Omar | RP | Rome Braves | 20 | 04/14/2005 | Long Beach | USA | Right | Right | 6' 0" | 175 lbs | - |
| Sanchez, Alberto | RP | Bowling Green Hot Rods | 24 | 05/27/2001 | Calabozo | VEN | Right | Right | 6' 1" | 205 lbs | - |
| Sanchez, Jose | 1B | Free Agent | 27 | 08/27/1997 | Matagalpa | NCA | Right | Right | 6' 0" | 195 lbs | - |
| Santiago, Antonio | SS | Greensboro Grasshoppers | 22 | 07/30/2002 | Willemstad | CUR | Right | Right | 6' 2" | 190 lbs | - |
| Saracino, Corey | CL | Brooklyn Cyclones | 24 | 10/14/2000 | Los Angeles | USA | Left | Right | 6' 2" | 210 lbs | - |
| Schowalter, Daniel | SP | Asheville Tourists | 24 | 05/13/2001 | Dunbar | USA | Right | Right | 5' 11" | 185 lbs | - |
| Schwander, Devin | C | Rome Braves | 23 | 03/01/2002 | Birmingham | USA | Right | Right | 6' 0" | 200 lbs | - |
| Seifert, Zach | SP | Greenville Drive | 21 | 10/24/2003 | Folcroft | USA | Right | Right | 6' 1" | 190 lbs | - |
| Serrano, Felix | CF | Hickory Crawdads | 24 | 08/18/2000 | Santiago | DOM | Right | Right | 6' 2" | 215 lbs | - |
| Serrano, Orlando | 3B | Greensboro Grasshoppers | 22 | 08/12/2002 | Caracas | VEN | Switch | Right | 5' 9" | 195 lbs | - |
| Shaffer, Jeff | 1B | Free Agent | 22 | 05/21/2003 | Glenvar Heights | USA | Left | Left | 6' 2" | 205 lbs | - |
| Sheppard, Justin | 3B | Free Agent | 25 | 03/29/2000 | Fort Worth | USA | Right | Right | 6' 0" | 215 lbs | - |
| Shields, John | C | Free Agent | 23 | 09/14/2001 | North Miami | USA | Right | Right | 5' 10" | 190 lbs | - |
| Shrout, Alan | 3B | Greenville Drive | 24 | 04/30/2001 | Plymouth | USA | Right | Right | 6' 0" | 200 lbs | $1,500,000 |
| Silva, Carlos | RP | Free Agent | 24 | 05/25/2001 | Barquisimeto | VEN | Right | Right | 6' 0" | 190 lbs | - |
| Simmons, Nick | 3B | Hudson Valley Renegades | 23 | 09/26/2001 | Wausau | USA | Right | Right | 6' 4" | 205 lbs | $1,200,000 |
| Sloan, Pat | 2B | Greensboro Grasshoppers | 22 | 07/25/2002 | Cedar Hills | USA | Right | Right | 6' 2" | 195 lbs | - |
| Smith, Alex | 3B | Free Agent | 24 | 01/31/2001 | Lake Worth | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smith, Bobby | SP | Greensboro Grasshoppers | 20 | 09/20/2004 | Memphis | USA | Right | Right | 6' 0" | 180 lbs | - |
| Smith, Corey | LF | Greensboro Grasshoppers | 22 | 04/17/2003 | Kansas City | USA | Left | Left | 5' 10" | 170 lbs | - |
| Smith, Shane | RP | Free Agent | 24 | 02/14/2001 | Vandalia | USA | Right | Right | 5' 10" | 185 lbs | - |
| Smith, Zack | RP | Bowling Green Hot Rods | 24 | 08/08/2000 | Elk Plain | USA | Left | Left | 5' 10" | 190 lbs | - |
| Snyder, Matt | RP | Wilmington Blue Rocks | 24 | 12/19/2000 | Fort Lauderdale | USA | Right | Right | 6' 1" | 195 lbs | - |
| Soria, Melvin | RP | Free Agent | 28 | 04/14/1997 | Caguas | PUR | Switch | Right | 6' 1" | 195 lbs | - |
| Sotelo, Jordan | SS | Free Agent | 23 | 01/20/2002 | Baníca | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Soto, Cesar | RP | Winston-Salem Dash | 21 | 12/28/2003 | Santo Domingo | DOM | Switch | Right | 6' 1" | 190 lbs | - |
| Spletter, Bill | C | Asheville Tourists | 24 | 07/04/2000 | Dallas | USA | Right | Right | 6' 0" | 210 lbs | - |
| St. Dennis, Cody | CF | Winston-Salem Dash | 21 | 11/03/2003 | Clarion | USA | Right | Right | 6' 0" | 205 lbs | - |
| Stecker, John | C | Rome Braves | 25 | 06/08/2000 | Lake Worth | USA | Switch | Right | 6' 4" | 225 lbs | - |
| Stenger, Rolf | C | Rome Braves | 24 | 11/05/2000 | Cape Coral | USA | Right | Right | 6' 2" | 210 lbs | - |
| Stocker, J.P. | CF | Bowling Green Hot Rods | 23 | 12/19/2001 | Grapevine | USA | Right | Left | 6' 1" | 200 lbs | $1,500,000 |
| Sutherland, Ken | 2B | Hickory Crawdads | 17 | 11/21/2007 | Tucson | USA | Left | Right | 5' 11" | 165 lbs | - |
| Suzuki, Hikoo | SP | Asheville Tourists | 22 | 05/03/2003 | Tokyo | JPN | Right | Right | 5' 11" | 180 lbs | - |
| Sykes, Cameron | C | Aberdeen Ironbirds | 26 | 05/19/1999 | De Pere | USA | Right | Right | 6' 0" | 215 lbs | - |
