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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saavedra, Edwin | RP | Springfield Cardinals | 25 | 10/13/2000 | San Pedro de Macorís | DOM | Switch | Right | 6' 0" | 200 lbs | - |
| Sanchez, Jose | SP | Amarillo Sod Poodles | 24 | 01/26/2002 | Seven Trees | USA | Right | Right | 6' 2" | 195 lbs | - |
| Sandoval, Willie | 1B | Northwest Arkansas Naturals | 21 | 09/05/2004 | Santo Domingo | DOM | Right | Right | 6' 1" | 195 lbs | - |
| Sanguinetti, Marco | SP | Amarillo Sod Poodles | 22 | 06/06/2003 | Los Teques | VEN | Right | Left | 6' 0" | 185 lbs | - |
| Santos, Alberto | LF | Arkansas Travelers | 24 | 11/06/2001 | Jacksonville | USA | Switch | Left | 6' 1" | 200 lbs | $2,200,000 |
| Santos, William | 1B | Free Agent | 25 | 04/17/2000 | Santo Domingo | DOM | Left | Left | 6' 2" | 210 lbs | - |
| Sarmiento, Nestor | 3B | Springfield Cardinals | 22 | 09/07/2003 | Sosúa | DOM | Right | Right | 6' 1" | 185 lbs | - |
| Schaffert, Adam | C | Springfield Cardinals | 26 | 04/14/1999 | Rochester | USA | Right | Right | 5' 10" | 190 lbs | $4,200,000 |
| Scheffler, Jason | SP | Free Agent | 28 | 01/14/1998 | Los Angeles | USA | Left | Right | 6' 1" | 200 lbs | - |
| Schuman, Bryan | 2B | Midland RockHounds | 20 | 12/08/2005 | Lindsborg | USA | Right | Right | 6' 0" | 175 lbs | - |
| Schwartz, Terry | SP | Tulsa Drillers | 23 | 01/24/2003 | Sunrise Manor | USA | Right | Right | 6' 0" | 190 lbs | - |
| Scott, Jim | C | Springfield Cardinals | 26 | 01/06/2000 | Holmes Beach | USA | Right | Right | 6' 2" | 225 lbs | $2,200,000 |
| Servin, Alex | C | Midland RockHounds | 23 | 12/23/2002 | Guanabacoa | CUB | Right | Right | 6' 2" | 220 lbs | - |
| Shaw, Scott | RP | Amarillo Sod Poodles | 23 | 09/27/2002 | Metairie | USA | Left | Left | 6' 0" | 195 lbs | - |
| Sheppard, Ron | LF | Northwest Arkansas Naturals | 24 | 10/11/2001 | Eustis | USA | Right | Right | 6' 3" | 220 lbs | - |
| Shultz, Matt | SP | Free Agent | 24 | 10/08/2001 | Broken Arrow | USA | Right | Right | 5' 9" | 185 lbs | - |
| Simmons, Stephen | SP | Free Agent | 26 | 12/25/1999 | Ashland | USA | Right | Right | 6' 0" | 200 lbs | - |
| Simon, Mike | RF | Northwest Arkansas Naturals | 22 | 11/10/2003 | Lawrence | USA | Right | Right | 6' 2" | 210 lbs | - |
| Sims, Brian | SP | Frisco RoughRiders | 24 | 06/08/2001 | New York | USA | Right | Right | 6' 3" | 200 lbs | - |
| Smart, Greg | CF | Free Agent | 25 | 10/26/2000 | Gatesville | USA | Right | Left | 6' 1" | 200 lbs | - |
| Smith, Billy | RP | Amarillo Sod Poodles | 23 | 05/18/2002 | Robinson | USA | Left | Right | 6' 0" | 190 lbs | - |
| Smith, Jesse | RP | Wichita Wind Surge | 24 | 07/02/2001 | Maquoketa | USA | Switch | Right | 6' 2" | 205 lbs | $3,600,000 |
| Smith, Joe | 2B | Frisco RoughRiders | 21 | 06/26/2004 | Geneva | USA | Right | Right | 6' 2" | 185 lbs | - |
| Smith, Joey | SS | Corpus Christi Hooks | 26 | 08/19/1999 | Smithfield | USA | Right | Right | 6' 1" | 200 lbs | - |
| Smith, Josh | 2B | Free Agent | 27 | 10/10/1998 | Fairview | USA | Right | Right | 6' 0" | 185 lbs | - |
| Smith, Josh | 1B | Midland RockHounds | 23 | 08/07/2002 | Viera East | USA | Right | Right | 6' 0" | 210 lbs | - |
| Smith, Paul | RP | Springfield Cardinals | 24 | 03/07/2002 | Washington | USA | Right | Left | 6' 0" | 190 lbs | $740,000 |
| Smith, Travis | 3B | Frisco RoughRiders | 21 | 07/10/2004 | Medina | USA | Right | Right | 6' 0" | 185 lbs | - |
| Smith, Zachary | LF | Midland RockHounds | 22 | 06/18/2003 | Macclenny | USA | Right | Right | 6' 1" | 200 lbs | - |
| Smithley, Mike | LF | Free Agent | 25 | 12/06/2000 | Smithfield | USA | Left | Right | 6' 2" | 215 lbs | - |
| Sorola, Antonio | RP | Free Agent | 27 | 12/17/1998 | Maracaibo | VEN | Left | Left | 6' 0" | 200 lbs | - |
| Soto, Jose | RP | Tulsa Drillers | 21 | 04/22/2004 | Brooklyn | USA | Right | Right | 6' 1" | 180 lbs | - |
| Soto, Miguel | CF | Northwest Arkansas Naturals | 23 | 11/06/2002 | Bajos de Haina | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Spear, Cody | SP | Free Agent | 25 | 02/20/2001 | Lawrence Township | USA | Right | Right | 6' 2" | 205 lbs | - |
| Spina, Adam | SP | Corpus Christi Hooks | 21 | 10/25/2004 | Miramar Beach | USA | Switch | Right | 5' 11" | 175 lbs | - |
| Spletter, Bill | 1B | Corpus Christi Hooks | 25 | 07/04/2000 | Dallas | USA | Right | Right | 6' 0" | 205 lbs | - |
| Stack, Brad | C | Northwest Arkansas Naturals | 23 | 07/29/2002 | Kansas City | USA | Switch | Right | 6' 0" | 215 lbs | - |
| Steinmetz, Fred | RP | Midland RockHounds | 26 | 10/20/1999 | Joliet | USA | Right | Right | 6' 0" | 200 lbs | - |
| Stephens, James | SP | Free Agent | 25 | 06/14/2000 | Warren | USA | Right | Right | 6' 1" | 195 lbs | - |
| Storm, Kyle | SP | Midland RockHounds | 26 | 03/04/2000 | New Berlin | USA | Right | Right | 6' 1" | 200 lbs | - |
| Stromquist, Rick | C | Free Agent | 25 | 08/20/2000 | Denver | USA | Right | Right | 6' 1" | 210 lbs | - |
| Sutherland, Gregg | SP | Frisco RoughRiders | 22 | 08/05/2003 | Houston | USA | Left | Left | 5' 10" | 175 lbs | - |
| Suzuki, Hikoo | RP | Corpus Christi Hooks | 22 | 05/03/2003 | Tokyo | JPN | Right | Right | 5' 11" | 180 lbs | - |
| Swiderski, Josh | RP | Wichita Wind Surge | 25 | 02/09/2001 | Monroe Township, Gloucester County | USA | Left | Left | 5' 10" | 185 lbs | - |
| Szymoniak, Jamie | RP | Tulsa Drillers | 24 | 02/23/2002 | Mariemont | USA | Switch | Right | 6' 1" | 190 lbs | - |
