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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saavedra, Edwin | SP | Springfield Cardinals | 25 | 10/13/2000 | San Pedro de Macorís | DOM | Switch | Right | 6' 0" | 200 lbs | - |
| Salzman, Korey | LF | Wichita Wind Surge | 24 | 02/12/2001 | Encantada-Ranchito El Calaboz | USA | Left | Left | 6' 2" | 200 lbs | $4,000,000 |
| Sarmiento, Nestor | 3B | Springfield Cardinals | 22 | 09/07/2003 | Sosúa | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Scheffler, Jason | RP | Amarillo Sod Poodles | 27 | 01/14/1998 | Los Angeles | USA | Left | Right | 6' 1" | 200 lbs | - |
| Schuman, Bryan | 2B | Midland RockHounds | 20 | 12/08/2005 | Lindsborg | USA | Right | Right | 6' 0" | 175 lbs | - |
| Schwartz, Terry | SP | Tulsa Drillers | 22 | 01/24/2003 | Sunrise Manor | USA | Right | Right | 6' 0" | 185 lbs | - |
| Servin, Alex | C | Midland RockHounds | 22 | 12/23/2002 | Guanabacoa | CUB | Right | Right | 6' 2" | 220 lbs | - |
| Shaw, Scott | RP | Amarillo Sod Poodles | 23 | 09/27/2002 | Metairie | USA | Left | Left | 6' 0" | 190 lbs | - |
| Shoemaker, Sam | 3B | Free Agent | 25 | 01/27/2000 | North Hempstead | USA | Right | Right | 6' 0" | 200 lbs | - |
| Shuck, David | LF | Free Agent | 26 | 11/19/1999 | Reinbeck | USA | Left | Left | 5' 10" | 180 lbs | - |
| Simmons, Stephen | RP | Amarillo Sod Poodles | 25 | 12/25/1999 | Ashland | USA | Right | Right | 6' 0" | 200 lbs | - |
| Simmons, Steve | RP | Northwest Arkansas Naturals | 23 | 08/11/2002 | Hobart | USA | Left | Left | 6' 2" | 200 lbs | - |
| Smart, Greg | CF | Northwest Arkansas Naturals | 25 | 10/26/2000 | Gatesville | USA | Right | Left | 6' 1" | 200 lbs | $2,800,000 |
| Smith, Jesse | SP | Wichita Wind Surge | 24 | 07/02/2001 | Maquoketa | USA | Switch | Right | 6' 2" | 210 lbs | $3,600,000 |
| Smith, Joey | SS | Corpus Christi Hooks | 26 | 08/19/1999 | Smithfield | USA | Right | Right | 6' 1" | 200 lbs | - |
| Smith, Josh | SS | Wichita Wind Surge | 27 | 10/10/1998 | Fairview | USA | Right | Right | 6' 0" | 185 lbs | - |
| Smith, Josh | 1B | Midland RockHounds | 23 | 08/07/2002 | Viera East | USA | Right | Right | 6' 0" | 215 lbs | - |
| Smith, Matt | SP | Corpus Christi Hooks | 22 | 08/28/2003 | Exeter | USA | Right | Right | 6' 0" | 185 lbs | - |
| Smith, Travis | 2B | Frisco RoughRiders | 21 | 07/10/2004 | Medina | USA | Right | Right | 6' 0" | 185 lbs | - |
| Smith, Zachary | LF | Midland RockHounds | 22 | 06/18/2003 | Macclenny | USA | Right | Right | 6' 1" | 200 lbs | - |
| Smithley, Mike | CF | Northwest Arkansas Naturals | 25 | 12/06/2000 | Smithfield | USA | Left | Right | 6' 2" | 210 lbs | - |
| Sorola, Antonio | RP | Free Agent | 26 | 12/17/1998 | Maracaibo | VEN | Left | Left | 6' 0" | 200 lbs | - |
| Soto, Jose | RP | Tulsa Drillers | 21 | 04/22/2004 | Brooklyn | USA | Right | Right | 6' 1" | 180 lbs | - |
| Spencer, Tyler | 1B | Tulsa Drillers | 22 | 09/07/2003 | Long Beach | USA | Left | Left | 6' 0" | 205 lbs | - |
| Stauffer, Jon | SP | Free Agent | 24 | 08/29/2001 | Garland | USA | Right | Right | 5' 10" | 195 lbs | - |
| Steinmetz, Fred | RP | Midland RockHounds | 26 | 10/20/1999 | Joliet | USA | Right | Right | 6' 0" | 200 lbs | - |
| Stephens, James | RP | Arkansas Travelers | 25 | 06/14/2000 | Warren | USA | Right | Right | 6' 1" | 195 lbs | - |
| Storm, Kyle | SP | Midland RockHounds | 25 | 03/04/2000 | New Berlin | USA | Right | Right | 6' 1" | 200 lbs | - |
| Stromquist, Rick | C | San Antonio Missions | 25 | 08/20/2000 | Denver | USA | Right | Right | 6' 1" | 210 lbs | - |
| Szymoniak, Jamie | RP | Tulsa Drillers | 23 | 02/23/2002 | Mariemont | USA | Switch | Right | 6' 1" | 190 lbs | - |
