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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saidana, Omar | SP | Augusta GreenJackets | 21 | 04/14/2005 | Long Beach | USA | Right | Right | 6' 0" | 175 lbs | - |
| Sales, Josh | C | Salem Red Sox | 22 | 11/11/2003 | The Acreage | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sanchez, Juan | RP | Charleston RiverDogs | 21 | 01/06/2005 | Santo Domingo | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Sanchez, Raul | RP | Myrtle Beach Pelicans | 20 | 09/27/2005 | Castaic | USA | Left | Left | 6' 1" | 180 lbs | - |
| Santana, Dennis | 3B | Carolina Mudcats | 24 | 03/09/2002 | Aloha | USA | Right | Right | 6' 0" | 195 lbs | - |
| Santos, Victor | SP | Carolina Mudcats | 22 | 06/13/2004 | Luperón | DOM | Right | Right | 6' 3" | 195 lbs | - |
| Sarmiento, Juan | CF | Down East Wood Ducks | 24 | 06/10/2002 | Cabimas | VEN | Right | Right | 6' 0" | 195 lbs | - |
| Schreiber, Karl | 1B | Lynchburg Hillcats | 23 | 03/28/2003 | LaPlace | USA | Right | Right | 6' 2" | 210 lbs | - |
| Schumpert, Brendan | SP | Delmarva Shorebirds | 21 | 12/29/2004 | Crestwood | USA | Switch | Left | 5' 10" | 180 lbs | - |
| Scott, Danny | 2B | Delmarva Shorebirds | 24 | 06/03/2002 | Glendora | USA | Right | Right | 6' 0" | 185 lbs | - |
| Scott, Mike | RP | Charleston RiverDogs | 23 | 12/10/2002 | Lochearn | USA | Right | Right | 6' 1" | 195 lbs | - |
| Shadinger, Walter | RP | Free Agent | 23 | 08/18/2002 | New York | USA | Right | Right | 6' 0" | 190 lbs | - |
| Shadrick, Glenn | RP | Down East Wood Ducks | 23 | 02/20/2003 | Camanche | USA | Right | Right | 6' 2" | 195 lbs | - |
| Shafer, Mike | RF | Augusta GreenJackets | 19 | 05/07/2007 | Vineyard | USA | Left | Right | 6' 2" | 180 lbs | - |
| Shaw, Graham | RP | Salem Red Sox | 20 | 09/04/2005 | Laurel | USA | Left | Left | 6' 0" | 175 lbs | - |
| Sheehan, Ryan | CF | Delmarva Shorebirds | 21 | 11/02/2004 | Shreveport | USA | Left | Right | 6' 1" | 180 lbs | - |
| Sherwood, Pat | C | Myrtle Beach Pelicans | 24 | 04/19/2002 | Ronkonkoma | USA | Right | Right | 6' 0" | 205 lbs | - |
| Silva, Sergio | 1B | Delmarva Shorebirds | 21 | 03/28/2005 | Santiago | DOM | Left | Left | 6' 1" | 175 lbs | - |
| Simmons, Steve | RP | Columbia Fireflies | 23 | 08/11/2002 | Hobart | USA | Left | Left | 6' 2" | 200 lbs | - |
| Simon, Mike | RF | Columbia Fireflies | 22 | 11/10/2003 | Lawrence | USA | Right | Right | 6' 2" | 215 lbs | - |
| Skinner, Scott | SP | Myrtle Beach Pelicans | 23 | 06/28/2003 | Houston | USA | Right | Right | 5' 11" | 180 lbs | - |
| Smith, Brad | RP | Lynchburg Hillcats | 19 | 12/08/2006 | Anaheim | USA | Right | Right | 5' 10" | 165 lbs | - |
| Smith, Jimmy | 3B | Lynchburg Hillcats | 19 | 10/01/2006 | Uhrichsville | USA | Switch | Right | 6' 0" | 175 lbs | - |
| Snyder, Mike | RP | Fredericksburg Nationals | 22 | 10/04/2003 | Aurora | USA | Right | Right | 6' 0" | 185 lbs | - |
| Snyder, Pete | SP | Carolina Mudcats | 20 | 06/14/2006 | Lakewood | USA | Right | Right | 6' 2" | 190 lbs | - |
| Somoza, Raul | RF | Down East Wood Ducks | 21 | 12/31/2004 | Greenfield Township (Lackawanna County) | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Soria, John | CL | Myrtle Beach Pelicans | 23 | 06/16/2003 | Crown Point | USA | Left | Left | 6' 4" | 210 lbs | - |
| Spicer, Dave | 2B | Columbia Fireflies | 22 | 12/15/2003 | Pine Hills | USA | Right | Right | 6' 0" | 180 lbs | - |
| Sporing, Andy | SP | Fayetteville Woodpeckers | 19 | 09/08/2006 | Georgetown | USA | Right | Right | 6' 5" | 200 lbs | - |
| St. Dennis, Cody | CF | Kannapolis Cannon Ballers | 22 | 11/03/2003 | Clarion | USA | Right | Right | 6' 0" | 205 lbs | - |
| Stanton, Erick | RP | Salem Red Sox | 22 | 12/26/2003 | Chula Vista | USA | Right | Right | 6' 0" | 195 lbs | - |
| Stein, Dan | 1B | Kannapolis Cannon Ballers | 21 | 03/26/2005 | New York | USA | Right | Right | 6' 6" | 240 lbs | - |
| Stephens, Rick | 1B | Fredericksburg Nationals | 22 | 09/22/2003 | Amherst | USA | Left | Left | 6' 0" | 205 lbs | - |
| Stewart, Brian | SP | Down East Wood Ducks | 23 | 03/22/2003 | Shamong | USA | Right | Right | 6' 0" | 190 lbs | - |
| Stout, Rich | SP | Kannapolis Cannon Ballers | 22 | 05/31/2004 | Hampton Township | USA | Left | Right | 6' 4" | 200 lbs | - |
| Stuart, Justin | LF | Charleston RiverDogs | 23 | 09/14/2002 | Owatonna | USA | Left | Right | 6' 2" | 215 lbs | - |
| Suarez, Andy | SP | Salem Red Sox | 22 | 01/25/2004 | San Miguelito | PAN | Switch | Right | 6' 1" | 180 lbs | - |
| Summitt, Greg | RF | Down East Wood Ducks | 20 | 11/13/2005 | West Norriton | USA | Right | Right | 6' 1" | 185 lbs | - |
