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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Eads, Daniel | RP | Chicago White Sox | 38 | 09/14/1987 | New York | USA | Left | Left | 6' 1" | 210 lbs | $740,000 |
| Ebel, Klaus | C | San Francisco Giants | 24 | 02/01/2002 | Sanford | USA | Right | Right | 6' 0" | 205 lbs | $740,000 |
| Edvalson, Chris | SP | Boston Red Sox | 25 | 07/16/2001 | Carlstadt | USA | Right | Right | 6' 0" | 190 lbs | $4,800,000 |
| Elder, Jamie | 3B | Athletics | 18 | 08/19/2007 | Live Oak (Sutter County) | USA | Right | Right | 6' 2" | 195 lbs | - |
| Elizondo, Ivan | SP | Free Agent | 30 | 10/01/1995 | Duncanville | USA | Right | Right | 6' 0" | 200 lbs | - |
| Elliott, Jaden | RP | Minnesota Twins | 25 | 11/08/2000 | Hialeah | USA | Right | Left | 6' 0" | 200 lbs | - |
| Elsensohn, Joe | LF | Arizona Diamondbacks | 26 | 03/13/2000 | Lancaster | USA | Left | Left | 6' 5" | 210 lbs | $11,000,000 |
| Elul, Matt | C | New York Mets | 25 | 11/11/2000 | Greenwood | USA | Right | Right | 6' 0" | 215 lbs | $4,600,000 |
| Enge, Bill | SP | Minnesota Twins | 33 | 08/23/1992 | Perrysburg | USA | Right | Right | 5' 11" | 195 lbs | $6,800,000 |
| Engelsman, Jarne | RF | Athletics | 22 | 05/27/2004 | Noord | ARU | Left | Left | 6' 3" | 210 lbs | - |
| Enos, Bryan | RP | New York Mets | 23 | 04/17/2003 | Ocala | USA | Right | Right | 6' 1" | 190 lbs | $740,000 |
| Episcopo, Dustin | RP | Arizona Diamondbacks | 28 | 07/05/1998 | Lubbock | USA | Left | Right | 6' 0" | 200 lbs | $740,000 |
| Escobedo, Willie | LF | Free Agent | 29 | 05/01/1997 | Santo Domingo | DOM | Switch | Right | 6' 3" | 225 lbs | - |
| Escudero, Alex | SP | Free Agent | 29 | 12/28/1996 | San Francisco de Macorís | DOM | Right | Right | 6' 2" | 205 lbs | - |
| Espargosa, Gino | LF | New York Yankees | 16 | 02/24/2010 | Maracaibo | VEN | Right | Left | 6' 1" | 175 lbs | - |
| Esparza, Alejandro | RP | Free Agent | 27 | 04/10/1999 | Guarumal | PAN | Right | Right | 6' 2" | 200 lbs | - |
| Esparza, Ed | SP | Washington Nationals | 16 | 04/27/2010 | San Miguelito | PAN | Right | Right | 6' 0" | 170 lbs | - |
| Espinal, Cesar | RP | St. Louis Cardinals | 26 | 12/28/1999 | Torrance | USA | Right | Right | 6' 0" | 185 lbs | $2,240,000 |
| Espinosa, Manuel | LF | Minnesota Twins | 16 | 10/01/2009 | Valle de la Pascua | VEN | Right | Right | 6' 1" | 180 lbs | - |
| Espinosa, Marty | 1B | Boston Red Sox | 38 | 05/13/1988 | Higüey | DOM | Right | Right | 6' 6" | 280 lbs | $12,900,000 |
| Espinoza, David | C | Houston Astros | 28 | 02/03/1998 | Palo Negro | VEN | Right | Right | 6' 0" | 200 lbs | $13,500,000 |
| Esquilin, Angelo | 1B | River Hills Rockets | 25 | 11/07/2000 | La Canela | DOM | Left | Left | 6' 1" | 225 lbs | $740,000 |
| Esquivel, Adrian | LF | Boston Red Sox | 27 | 06/17/1999 | Los Mochis | MEX | Right | Right | 6' 4" | 205 lbs | $15,800,000 |
| Estrada, Juan | SS | Athletics | 26 | 05/05/2000 | Santo Domingo | DOM | Right | Right | 6' 1" | 195 lbs | $740,000 |
| Estrada, Victor | C | Los Angeles Dodgers | 16 | 04/29/2010 | Barcelona | VEN | Right | Right | 5' 11" | 165 lbs | - |
| Evans, Danny | SP | Baltimore Orioles | 30 | 07/16/1996 | Chicago | USA | Right | Right | 6' 1" | 205 lbs | $9,300,000 |
| Eyer, Mike | RF | Washington Nationals | 27 | 08/19/1998 | New York | USA | Switch | Right | 6' 0" | 190 lbs | $2,680,000 |
