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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabbag, Tom | RP | Salt Lake Bees | 25 | 06/15/2001 | Aliquippa | USA | Right | Right | 5' 11" | 195 lbs | - |
| Salazar, Pedro | C | Round Rock Express | 24 | 04/12/2002 | Bajos de Haina | DOM | Left | Right | 6' 2" | 195 lbs | - |
| Salinas, John | RP | Albuquerque Isotopes | 22 | 12/26/2003 | Santo Domingo | DOM | Right | Right | 6' 0" | 195 lbs | - |
| Santo, Tyler | CL | Sacramento River Cats | 23 | 10/30/2002 | Charlotte | USA | Right | Right | 6' 1" | 195 lbs | - |
| Santorio, Gautier | SP | Reno Aces | 25 | 12/29/2000 | Canicattì | ITA | Left | Left | 5' 11" | 190 lbs | $3,800,000 |
| Santos, Alberto | RF | El Paso Chihuahuas | 24 | 11/06/2001 | Jacksonville | USA | Switch | Left | 6' 1" | 200 lbs | - |
| Schultz, Steve | RF | El Paso Chihuahuas | 25 | 10/02/2001 | Mesa | USA | Right | Left | 6' 1" | 195 lbs | - |
| Schwartz, Terry | SP | Oklahoma City Dodgers | 23 | 01/24/2003 | Sunrise Manor | USA | Right | Right | 6' 0" | 190 lbs | - |
| Scott, Andre | RF | Salt Lake Bees | 24 | 04/08/2002 | South Taft | USA | Right | Right | 6' 1" | 205 lbs | - |
| Scott, Devin | 1B | Sacramento River Cats | 23 | 01/18/2003 | Germantown | USA | Switch | Right | 6' 1" | 205 lbs | - |
| Seals, Jon | RF | Free Agent | 28 | 05/12/1998 | Markham | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Segura, Juan | SP | Free Agent | 27 | 03/19/1999 | Esperanza | DOM | Right | Right | 6' 4" | 215 lbs | - |
| Seligman, Bob | SP | Tacoma Rainiers | 25 | 05/01/2001 | Hernando | USA | Right | Right | 6' 2" | 205 lbs | - |
| Serna, Joel | SP | El Paso Chihuahuas | 25 | 01/11/2001 | Santo Domingo | DOM | Right | Right | 6' 3" | 200 lbs | $2,400,000 |
| Settles, Bill | SP | Las Vegas Aviators | 27 | 05/04/1999 | Barstow | USA | Right | Right | 5' 10" | 195 lbs | - |
| Shaw, Aaron | CL | Sugar Land Skeeters | 29 | 02/15/1997 | Smithtown | USA | Left | Right | 6' 0" | 195 lbs | $740,000 |
| Shaw, Brenden | RF | Las Vegas Aviators | 26 | 12/19/1999 | Landover Hills | USA | Left | Left | 5' 10" | 195 lbs | - |
| Sims, Brian | RP | Round Rock Express | 25 | 06/08/2001 | New York | USA | Right | Right | 6' 3" | 205 lbs | - |
| Slater, Toby | SS | Las Vegas Aviators | 25 | 04/05/2001 | Brisbane | AUS | Left | Right | 6' 0" | 190 lbs | - |
| Smith, Cameron | RP | Free Agent | 30 | 06/17/1996 | Brumley | USA | Left | Left | 6' 0" | 200 lbs | - |
| Smith, Matt | SP | Sugar Land Skeeters | 23 | 08/28/2003 | Exeter | USA | Right | Right | 6' 0" | 185 lbs | - |
| Solis, Luis | RP | Round Rock Express | 25 | 11/01/2000 | San Francisco de Macorís | DOM | Right | Right | 6' 4" | 215 lbs | - |
| Solorzano, Edgar | C | El Paso Chihuahuas | 24 | 10/24/2001 | Wichita | USA | Left | Right | 6' 3" | 230 lbs | $2,000,000 |
| Solt, Joey | RP | Free Agent | 21 | 09/06/2005 | Estes Park | USA | Switch | Right | 5' 11" | 170 lbs | - |
| Soto, Gus | 1B | Sugar Land Skeeters | 22 | 12/12/2003 | South Beloit | USA | Right | Right | 6' 2" | 190 lbs | - |
| Soto, Jose | RP | Oklahoma City Dodgers | 22 | 04/22/2004 | Brooklyn | USA | Right | Right | 6' 1" | 185 lbs | - |
| Spears, Mike | RP | Sacramento River Cats | 23 | 12/25/2002 | Carson | USA | Switch | Right | 6' 1" | 205 lbs | - |
| Spencer, Tyler | 1B | Reno Aces | 23 | 09/07/2003 | Long Beach | USA | Left | Left | 6' 0" | 205 lbs | - |
| Stack, Mike | CF | Las Vegas Aviators | 24 | 08/28/2002 | Upper Arlington | USA | Left | Left | 6' 1" | 195 lbs | - |
| Stafford, Jeremy | LF | Albuquerque Isotopes | 22 | 09/19/2004 | Fort Worth | USA | Left | Left | 6' 1" | 185 lbs | - |
| Suarez, Dan | SP | Albuquerque Isotopes | 23 | 02/12/2003 | Silver Spring | USA | Left | Left | 5' 10" | 180 lbs | - |
| Suarez, Jose | CF | Las Vegas Aviators | 24 | 10/08/2001 | San Cristóbal | DOM | Left | Right | 6' 1" | 195 lbs | - |
| Sutherland, Gregg | SP | Round Rock Express | 23 | 08/05/2003 | Houston | USA | Left | Left | 5' 10" | 175 lbs | - |
| Sutton, Brian | 1B | Round Rock Express | 25 | 02/19/2001 | Inkster | USA | Right | Right | 6' 1" | 215 lbs | - |
| Swanson, Jim | SP | Sacramento River Cats | 21 | 12/01/2004 | Denver | USA | Switch | Right | 6' 2" | 190 lbs | - |
| Sweet, Corey | C | Las Vegas Aviators | 24 | 01/31/2002 | New York | USA | Switch | Right | 6' 1" | 205 lbs | - |
| Syner, Sam | LF | Free Agent | 28 | 10/04/1998 | Palmview | USA | Switch | Right | 6' 0" | 205 lbs | - |
