| November 16, 2025 | @ Auburn Tigers | W 64-62 | 1-0 | J. James 22 | A. Powell 5 | T. Jefferson 11 |
| November 23, 2025 | OLD DOMINION MONARCHS | W 75-63 | 2-0 | J. James 16 | J. James 4 | A. Powell 23 |
| November 26, 2025 | @ Mississippi State Bulldogs | L 69-84 | 2-1 | E. Roland 13 | J. James 3 | A. Powell 6 |
| November 30, 2025 | MOREHEAD STATE EAGLES | W 70-51 | 3-1 | A. Powell 14 | J. James 4 | T. Jefferson 10 |
| December 7, 2025 | DENVER PIONEERS | W 79-65 | 4-1 | A. Powell 20 | J. James 8 | A. Powell 17 |
| December 13, 2025 | CINCINNATI BEARCATS | L 71-82 | 4-2 | J. James 19 | T. Jefferson 4 | A. Powell 6 |
| December 17, 2025 | NEW MEXICO STATE AGGIES | W 57-47 | 5-2 | E. Roland 12 | J. James 4 | J. James 7 |
| December 21, 2025 | WAKE FOREST DEMON DEACONS | L 73-86 | 5-3 | T. Jefferson 16 | J. James 4 | T. Jefferson 10 |
| December 23, 2025 | MISSOURI STATE BEARS Empire Classic | L 70-92 | 5-4 | E. Roland 18 | E. Roland 5 | A. Powell 13 |
| December 26, 2025 | DEPAUL BLUE DEMONS* | W 81-79 | 6-4 | J. James 19 | A. Powell 5 | A. Powell 14 |
| December 28, 2025 | @ #17 Providence Friars* | W 85-61 | 7-4 | A. Powell 18 | J. James 5 | T. Jefferson 6 |
| December 30, 2025 | @ Georgetown Hoyas* | L 55-72 | 7-5 | A. Powell 11 | J. James 5 | T. Jefferson 9 |
| January 2, 2026 | CREIGHTON BLUE JAYS* | L 63-64 | 7-6 | A. Powell 13 | J. James 5 | A. Powell 12 |
| January 6, 2026 | @ Butler Bulldogs* | W 77-66 | 8-6 | J. James 20 | J. James 7 | A. Powell 8 |
| January 9, 2026 | @ St. Johns Red Storm* | L 67-77 | 8-7 | A. Powell 16 | E. Roland 4 | A. Powell 7 |
| January 13, 2026 | SETON HALL PIRATES* | W 85-59 | 9-7 | L. McKamey 14 | J. James 5 | A. Powell 8 |
| January 16, 2026 | VILLANOVA WILDCATS* | W 76-55 | 10-7 | J. James 23 | J. James 4 | T. Jefferson 7 |
| January 18, 2026 | @ Marquette Golden Eagles* | L 60-79 | 10-8 | E. Roland 17 | J. James 5 | T. Jefferson 10 |
| January 20, 2026 | @ #4 Connecticut Huskies* | L 58-84 | 10-9 | J. James 28 | J. James 2 | T. Jefferson 12 |
| January 25, 2026 | ST. JOHNS RED STORM* | W 89-70 | 11-9 | J. James 21 | T. Jefferson 3 | T. Jefferson 12 |
| February 3, 2026 | @ DePaul Blue Demons* | L 76-80 | 11-10 | J. James 29 | B. Harper 6 | B. Harper 8 |
| February 6, 2026 | @ Creighton Blue Jays* | L 78-97 | 11-11 | J. James 30 | J. James 4 | T. Jefferson 10 |
| February 10, 2026 | GEORGETOWN HOYAS* | W 77-65 | 12-11 | J. James 26 | A. Lloyd 7 | B. Harper 9 |
| February 13, 2026 | #24 PROVIDENCE FRIARS* | L 67-83 | 12-12 | J. James 19 | J. James 5 | B. Harper 5 |
| February 15, 2026 | BUTLER BULLDOGS* | L 81-85 | 12-13 | J. James 23 | J. James 7 | L. McKamey 4 |
| February 22, 2026 | @ Seton Hall Pirates* | L 55-67 | 12-14 | J. James 20 | A. Lloyd 4 | A. Powell 7 |
| February 24, 2026 | @ #25 Villanova Wildcats* | L 78-91 | 12-15 | A. Powell 20 | L. McKamey 5 | A. Powell 12 |
| March 1, 2026 | #2 CONNECTICUT HUSKIES* | W 79-59 | 13-15 | E. Roland 21 | J. James 8 | L. McKamey 7 |
| March 3, 2026 | #22 MARQUETTE GOLDEN EAGLES* | W 73-72 | 14-15 | A. Powell 26 | J. James 5 | A. Powell 8 |
| March 9, 2026 | DEPAUL BLUE DEMONS Big East Tournament | W 71-57 | 15-15 | A. Powell 20 | J. James 6 | A. Powell 16 |
| March 10, 2026 | @ #25 Marquette Golden Eagles Big East Tournament | L 42-61 | 15-16 | E. Roland 11 | A. Powell 3 | A. Powell 13 |
