| November 15, 2027 | BELMONT BRUINS | W 80-59 | 1-0 | L. Evans 16 | L. Evans 3 | E. Taylor 8 |
| November 18, 2027 | SOUTHERN MISSISSIPPI GOLDEN EAGLES | W 83-72 | 2-0 | E. Taylor 16 | L. Evans 5 | M. Battier 8 |
| November 22, 2027 | @ #1 Kansas Jayhawks | L 58-77 | 2-1 | E. Taylor 15 | L. Evans 6 | B. Jenkins 7 |
| November 29, 2027 | PEPPERDINE WAVES | W 73-64 | 3-1 | M. Stapleton 14 | M. Cherry 7 | E. Taylor 8 |
| December 6, 2027 | YALE BULLDOGS | L 55-75 | 3-2 | L. Evans 15 | L. Evans 5 | E. Taylor 7 |
| December 13, 2027 | @ #1 Marquette Golden Eagles | W 70-57 | 4-2 | E. Taylor 19 | L. Evans 8 | E. Taylor 11 |
| December 16, 2027 | UC-SANTA BARBARA GAUCHOS Battle 4 Atlantis | W 89-72 | 5-2 | L. Evans 19 | L. Evans 7 | L. Evans 8 |
| December 17, 2027 | XAVIER MUSKETEERS Battle 4 Atlantis | W 83-74 | 6-2 | E. Taylor 21 | L. Evans 6 | B. Jenkins 7 |
| December 18, 2027 | @ Louisville Cardinals (8-1, 5-1 Home) Battle 4 Atlantis | - | | | | |
| December 20, 2027 | TOLEDO ROCKETS (5-4, 3-3 Away) | - | | | | |
| December 22, 2027 | SOUTHERN UTAH THUNDERBIRDS (2-8, 1-6 Away) | - | | | | |
| December 26, 2027 | @ Washington Huskies (5-3, 0-0, 5-2 Home)* | - | | | | |
| December 28, 2027 | OHIO STATE BUCKEYES (6-3, 0-0, 1-2 Away)* | - | | | | |
| January 2, 2028 | MINNESOTA GOLDEN GOPHERS (7-3, 0-0, 0-2 Away)* | - | | | | |
| January 4, 2028 | @ Northwestern Wildcats (5-3, 0-0, 5-1 Home)* | - | | | | |
| January 9, 2028 | @ Oregon Ducks (4-5, 0-0, 3-3 Home)* | - | | | | |
| January 11, 2028 | @ UCLA Bruins (8-2, 0-0, 5-1 Home)* | - | | | | |
| January 16, 2028 | MICHIGAN WOLVERINES (10-0, 0-0, 0-0 Away)* | - | | | | |
| January 18, 2028 | @ Purdue Boilermakers (6-3, 0-0, 5-2 Home)* | - | | | | |
| January 23, 2028 | PENN STATE NITTANY LIONS (3-4, 0-0, 0-1 Away)* | - | | | | |
| January 25, 2028 | NEBRASKA CORNHUSKERS (4-4, 0-0, 0-1 Away)* | - | | | | |
| January 30, 2028 | @ Michigan State Spartans (6-1, 0-0, 5-0 Home)* | - | | | | |
| February 1, 2028 | MARYLAND TERRAPINS (6-2, 0-0, 0-1 Away)* | - | | | | |
| February 6, 2028 | RUTGERS SCARLET KNIGHTS (5-4, 0-0, 0-1 Away)* | - | | | | |
| February 8, 2028 | ILLINOIS FIGHTING ILLINI (6-3, 0-0, 0-1 Away)* | - | | | | |
| February 13, 2028 | @ Iowa Hawkeyes (3-5, 0-0, 3-2 Home)* | - | | | | |
| February 15, 2028 | SOUTHERN CALIFORNIA TROJANS (5-3, 0-0, 0-0 Away)* | - | | | | |
| February 20, 2028 | @ Indiana Hoosiers (4-4, 0-0, 3-1 Home)* | - | | | | |
| February 22, 2028 | @ Illinois Fighting Illini (6-3, 0-0, 6-1 Home)* | - | | | | |
| February 27, 2028 | @ Nebraska Cornhuskers (4-4, 0-0, 4-2 Home)* | - | | | | |
| March 1, 2028 | IOWA HAWKEYES (3-5, 0-0, 0-2 Away)* | - | | | | |
