| November 15, 2027 | @ Seton Hall Pirates | L 75-91 | 0-1 | A. Rhodes 16 | A. Rhodes 3 | J. Stevens 10 |
| November 18, 2027 | @ Davidson Wildcats Sunshine Slam | L 78-85 | 0-2 | J. Stevens 16 | D. Gomez 3 | J. Stevens 9 |
| November 22, 2027 | GEORGIA STATE PANTHERS | W 98-86 | 1-2 | J. Stevens 24 | M. Jordan 6 | A. Rhodes 6 |
| November 25, 2027 | LOUISIANA-LAFAYETTE RAGIN' CAJUNS | W 104-78 | 2-2 | R. Clayton 15 | M. Jordan 6 | A. Rhodes 6 |
| November 29, 2027 | BUCKNELL BISON | W 102-76 | 3-2 | R. Clayton 27 | D. Gomez 7 | J. Stevens 9 |
| December 2, 2027 | ALABAMA STATE HORNETS | W 85-79 | 4-2 | M. Jordan 15 | R. Clayton 4 | A. Rhodes 11 |
| December 5, 2027 | MD-BALTIMORE COUNTY RETRIEVERS | W 72-49 | 5-2 | C. Smith 16 | M. Jordan 5 | A. Rhodes 12 |
| December 13, 2027 | #12 TEXAS LONGHORNS | W 81-67 | 6-2 | R. Clayton 18 | M. Jordan 6 | M. Jordan 5 |
| December 20, 2027 | PORTLAND PILOTS | L 75-95 | 6-3 | A. Rhodes 16 | M. Jordan 4 | A. Rhodes 8 |
| December 26, 2027 | VIRGINIA TECH HOKIES* | L 79-91 | 6-4 | R. Clayton 24 | M. Jordan 7 | A. Rhodes 9 |
| December 28, 2027 | FLORIDA STATE SEMINOLES* | W 79-70 | 7-4 | J. Stevens 20 | M. Jordan 5 | W. Sanders 7 |
| January 2, 2028 | @ Boston College Eagles* | W 90-78 | 8-4 | R. Clayton 21 | D. Gomez 4 | R. Clayton 6 |
| January 4, 2028 | @ Miami (FL) Hurricanes* | W 71-66 | 9-4 | J. Stevens 16 | A. Rhodes 3 | A. Rhodes 9 |
| January 9, 2028 | #8 DUKE BLUE DEVILS* | L 75-86 | 9-5 | R. Clayton 18 | M. Jordan 4 | J. Stevens 12 |
| January 11, 2028 | CALIFORNIA GOLDEN BEARS* | W 90-71 | 10-5 | J. Stevens 31 | M. Jordan 9 | J. Stevens 8 |
| January 16, 2028 | @ Clemson Tigers* | L 72-87 | 10-6 | R. Clayton 21 | M. Jordan 10 | K. Sawyer 7 |
| January 18, 2028 | #15 PITTSBURGH PANTHERS* | L 59-81 | 10-7 | J. Stevens 11 | M. Jordan 4 | A. Rhodes 8 |
| January 23, 2028 | @ Stanford Cardinal* | W 77-65 | 11-7 | J. Stevens 16 | M. Jordan 5 | J. Stevens 8 |
| January 25, 2028 | @ #12 North Carolina Tar Heels* | L 61-68 | 11-8 | A. Rhodes 10 | M. Jordan 6 | A. Rhodes 7 |
| January 30, 2028 | @ Syracuse Orange* | L 80-96 | 11-9 | R. Clayton 19 | M. Jordan 7 | A. Burch 6 |
| February 1, 2028 | @ #9 Louisville Cardinals* | L 62-78 | 11-10 | J. Stevens 13 | M. Jordan 3 | J. Stevens 9 |
| February 6, 2028 | NC-STATE WOLFPACK* | L 67-84 | 11-11 | A. Rhodes 13 | T. Treadwell 3 | A. Rhodes 13 |
| February 8, 2028 | #7 VIRGINIA CAVALIERS* | L 68-88 | 11-12 | A. Rhodes 19 | M. Jordan 4 | A. Rhodes 9 |
| February 13, 2028 | @ #18 Georgia Tech Yellow Jackets* | L 78-87 | 11-13 | R. Clayton 17 | D. Gomez 4 | A. Rhodes 10 |
| February 15, 2028 | @ Southern Methodist Mustangs* | L 67-81 | 11-14 | R. Clayton 14 | M. Jordan 8 | A. Rhodes 10 |
| February 20, 2028 | NOTRE DAME FIGHTING IRISH* | W 98-83 | 12-14 | R. Clayton 19 | M. Jordan 10 | J. Stevens 6 |
| February 22, 2028 | MIAMI (FL) HURRICANES* | W 93-72 | 13-14 | R. Clayton 27 | M. Jordan 11 | J. Stevens 11 |
| February 27, 2028 | @ Virginia Tech Hokies* | L 66-76 | 13-15 | J. Stevens 15 | M. Jordan 5 | J. Stevens 11 |
| March 1, 2028 | BOSTON COLLEGE EAGLES* | L 76-78 | 13-16 | R. Clayton 19 | M. Jordan 5 | J. Stevens 6 |
| March 8, 2028 | @ Miami (FL) Hurricanes ACC Tournament | L 79-82 | 13-17 | A. Rhodes 20 | M. Jordan 6 | A. Rhodes 10 |
