| November 15, 2027 | @ Southern California Trojans | W 82-79 | 1-0 | H. Honeycutt 17 | D. Bond 6 | J. Norwood 9 |
| November 18, 2027 | RICE OWLS | W 88-70 | 2-0 | D. Bond 18 | D. Underwood 4 | J. Norwood 18 |
| November 22, 2027 | STONY BROOK SEAWOLVES | W 72-57 | 3-0 | M. Phillips 18 | M. Phillips 6 | J. Norwood 17 |
| November 29, 2027 | MERCER BEARS | W 75-55 | 4-0 | M. Phillips 21 | D. Bond 5 | J. Norwood 12 |
| December 2, 2027 | @ Purdue Boilermakers | W 98-86 | 5-0 | D. Bond 19 | D. Bond 5 | H. Honeycutt 13 |
| December 6, 2027 | DRAKE BULLDOGS | W 74-59 | 6-0 | M. Leatherman 23 | D. Bond 6 | H. Honeycutt 11 |
| December 13, 2027 | @ Saint Josephs Hawks | W 84-50 | 7-0 | D. Bond 18 | D. Underwood 4 | J. Norwood 14 |
| December 20, 2027 | WESTERN KENTUCKY HILLTOPPERS (4-4, 0-3 Away) | - | | | | |
| December 23, 2027 | RIDER BRONCS (1-7, 1-6 Away) Gulf Coast Showcase | - | | | | |
| December 26, 2027 | GEORGETOWN HOYAS (8-0, 0-0, 1-0 Away)* | - | | | | |
| December 28, 2027 | @ Xavier Musketeers (5-4, 0-0, 2-2 Home)* | - | | | | |
| December 30, 2027 | @ Connecticut Huskies (2-6, 0-0, 1-4 Home)* | - | | | | |
| January 2, 2028 | DEPAUL BLUE DEMONS (6-2, 0-0, 1-2 Away)* | - | | | | |
| January 4, 2028 | @ Seton Hall Pirates (9-1, 0-0, 5-1 Home)* | - | | | | |
| January 9, 2028 | CREIGHTON BLUE JAYS (8-2, 0-0, 0-0 Away)* | - | | | | |
| January 13, 2028 | PROVIDENCE FRIARS (7-3, 0-0, 1-0 Away)* | - | | | | |
| January 18, 2028 | @ Marquette Golden Eagles (10-1, 0-0, 5-1 Home)* | - | | | | |
| January 20, 2028 | @ Butler Bulldogs (6-4, 0-0, 2-1 Home)* | - | | | | |
| January 25, 2028 | @ Creighton Blue Jays (8-2, 0-0, 6-1 Home)* | - | | | | |
| January 27, 2028 | @ St. Johns Red Storm (4-4, 0-0, 3-2 Home)* | - | | | | |
| February 1, 2028 | SETON HALL PIRATES (9-1, 0-0, 1-0 Away)* | - | | | | |
| February 3, 2028 | @ Providence Friars (7-3, 0-0, 3-3 Home)* | - | | | | |
| February 8, 2028 | BUTLER BULLDOGS (6-4, 0-0, 1-3 Away)* | - | | | | |
| February 10, 2028 | MARQUETTE GOLDEN EAGLES (10-1, 0-0, 1-0 Away)* | - | | | | |
| February 17, 2028 | ST. JOHNS RED STORM (4-4, 0-0, 1-1 Away)* | - | | | | |
| February 22, 2028 | @ DePaul Blue Demons (6-2, 0-0, 5-0 Home)* | - | | | | |
| February 24, 2028 | @ Georgetown Hoyas (8-0, 0-0, 7-0 Home)* | - | | | | |
| March 1, 2028 | CONNECTICUT HUSKIES (2-6, 0-0, 0-1 Away)* | - | | | | |
| March 3, 2028 | XAVIER MUSKETEERS (5-4, 0-0, 2-1 Away)* | - | | | | |
