| November 15, 2027 | WYOMING COWBOYS | W 84-62 | 1-0 | G. Althusser 28 | K. Avery 10 | T. Johnson 15 |
| November 18, 2027 | STEPHEN F. AUSTIN LUMBERJACKS Emerald Coast Classic | W 85-73 | 2-0 | G. Althusser 24 | J. Hayes 7 | G. Althusser 9 |
| November 19, 2027 | BELMONT BRUINS Emerald Coast Classic | W 84-69 | 3-0 | G. Althusser 23 | K. Avery 8 | G. Althusser 8 |
| November 20, 2027 | @ #14 Brigham Young Cougars Emerald Coast Classic | W 75-66 | 4-0 | G. Althusser 27 | K. Avery 5 | G. Althusser 11 |
| November 22, 2027 | SAMFORD BULLDOGS | W 80-53 | 5-0 | J. Brown 27 | K. Avery 7 | T. Johnson 12 |
| November 25, 2027 | ARMY BLACK KNIGHTS | W 75-61 | 6-0 | G. Althusser 15 | K. Avery 4 | G. Althusser 14 |
| November 29, 2027 | @ UCLA Bruins | L 59-63 | 6-1 | T. Johnson 22 | K. Avery 6 | T. Johnson 12 |
| December 2, 2027 | @ #16 Providence Friars | W 86-60 | 7-1 | J. Brown 31 | K. Avery 12 | G. Althusser 10 |
| December 6, 2027 | @ Oregon Ducks | W 92-83 | 8-1 | K. Avery 26 | K. Avery 7 | T. Johnson 12 |
| December 13, 2027 | FAIRFIELD STAGS | W 85-68 | 9-1 | G. Althusser 29 | K. Avery 7 | T. Johnson 9 |
| December 20, 2027 | DELAWARE FIGHTIN' BLUE HENS | W 81-65 | 10-1 | T. Johnson 19 | G. Althusser 5 | G. Althusser 12 |
| December 26, 2027 | @ Syracuse Orange* | W 72-54 | 11-1 | K. Avery 24 | K. Avery 6 | T. Johnson 12 |
| December 28, 2027 | @ #9 Pittsburgh Panthers* | W 78-75 | 12-1 | T. Johnson 30 | K. Avery 7 | T. Johnson 15 |
| January 2, 2028 | NC-STATE WOLFPACK* | W 77-65 | 13-1 | K. Avery 25 | G. Althusser 6 | T. Johnson 11 |
| January 4, 2028 | @ Stanford Cardinal* | L 68-72 | 13-2 | G. Althusser 20 | K. Avery 6 | G. Althusser 11 |
| January 9, 2028 | #10 NORTH CAROLINA TAR HEELS* | W 69-58 | 14-2 | G. Althusser 11 | K. Avery 9 | G. Althusser 9 |
| January 11, 2028 | #9 LOUISVILLE CARDINALS* | W 105-103 OT | 15-2 | J. Brown 27 | K. Avery 13 | T. Johnson 17 |
| January 16, 2028 | FLORIDA STATE SEMINOLES* | W 72-56 | 16-2 | J. Brown 20 | K. Avery 8 | T. Johnson 11 |
| January 18, 2028 | SOUTHERN METHODIST MUSTANGS* | L 67-73 | 16-3 | J. Brown 21 | K. Avery 5 | T. Johnson 13 |
| January 23, 2028 | @ Miami (FL) Hurricanes* | L 59-77 | 16-4 | G. Althusser 18 | K. Avery 8 | G. Althusser 14 |
| January 25, 2028 | @ California Golden Bears* | W 86-70 | 17-4 | K. Avery 31 | K. Avery 4 | T. Johnson 14 |
| January 30, 2028 | VIRGINIA TECH HOKIES* | W 85-73 | 18-4 | G. Althusser 22 | K. Avery 7 | G. Althusser 11 |
| February 1, 2028 | @ Notre Dame Fighting Irish* | L 66-82 | 18-5 | T. Johnson 18 | K. Avery 5 | T. Johnson 11 |
| February 6, 2028 | @ #9 Duke Blue Devils* | L 70-75 | 18-6 | J. Brown 26 | K. Avery 7 | J. Hayes 13 |
| February 8, 2028 | @ Wake Forest Demon Deacons* | W 88-68 | 19-6 | K. Avery 17 | K. Avery 3 | T. Johnson 16 |
| February 13, 2028 | @ Boston College Eagles* | W 94-82 | 20-6 | G. Althusser 28 | K. Avery 10 | J. Hayes 10 |
| February 15, 2028 | #18 GEORGIA TECH YELLOW JACKETS* | L 95-98 OT | 20-7 | K. Avery 34 | K. Avery 8 | T. Johnson 14 |
| February 20, 2028 | CLEMSON TIGERS* | W 75-60 | 21-7 | G. Althusser 17 | K. Avery 8 | G. Althusser 8 |
| February 22, 2028 | STANFORD CARDINAL* | W 75-52 | 22-7 | J. Brown 21 | K. Avery 7 | J. Hayes 10 |
| February 27, 2028 | BOSTON COLLEGE EAGLES* | W 79-73 | 23-7 | J. Brown 17 | K. Avery 5 | G. Althusser 8 |
| March 1, 2028 | @ #12 Georgia Tech Yellow Jackets* | W 78-72 | 24-7 | G. Althusser 28 | K. Avery 13 | G. Althusser 10 |
| March 9, 2028 | SOUTHERN METHODIST MUSTANGS ACC Tournament | W 82-67 | 25-7 | K. Avery 23 | J. Hayes 5 | G. Althusser 10 |
| March 10, 2028 | @ Notre Dame Fighting Irish ACC Tournament | W 65-53 | 26-7 | K. Avery 22 | K. Avery 3 | G. Althusser 11 |
| March 11, 2028 | @ #7 North Carolina Tar Heels ACC Tournament | W 68-52 | 27-7 | K. Avery 21 | K. Avery 7 | G. Althusser 10 |
| March 12, 2028 | #12 PITTSBURGH PANTHERS ACC Tournament | W 77-60 | 28-7 | G. Althusser 25 | J. Brown 8 | G. Althusser 11 |
