| November 15, 2027 | SE MISSOURI STATE REDHAWKS | W 93-80 | 1-0 | G. Christiansen 23 | S. Scott 7 | G. Christiansen 6 |
| November 18, 2027 | @ Louisiana State Fighting Tigers | L 68-81 | 1-1 | M. Edgerson 16 | C. Dahle 5 | T. Jacobs 6 |
| November 22, 2027 | @ Tulane Green Wave | L 80-95 | 1-2 | D. Mitchell 23 | S. Scott 4 | D. Mitchell 10 |
| November 25, 2027 | HARVARD CRIMSON | L 82-95 | 1-3 | S. Scott 14 | C. Dahle 5 | G. Christiansen 6 |
| November 29, 2027 | @ Stanford Cardinal | W 67-60 | 2-3 | G. Christiansen 17 | G. Christiansen 4 | M. Edgerson 8 |
| December 6, 2027 | @ South Alabama Jaguars | L 77-84 | 2-4 | D. Mitchell 18 | C. Dahle 5 | C. Dahle 5 |
| December 9, 2027 | @ Utah Utes Jimmy V Classic | L 67-81 | 2-5 | D. Mitchell 14 | C. Dahle 12 | D. Mitchell 10 |
| December 12, 2027 | @ Kansas State Wildcats | L 63-90 | 2-6 | G. Christiansen 19 | C. Dahle 7 | M. Edgerson 8 |
| December 20, 2027 | @ #5 Florida Gators | L 57-79 | 2-7 | C. Dahle 13 | M. Edgerson 3 | M. Edgerson 11 |
| December 26, 2027 | ILLINOIS STATE REDBIRDS* | L 66-77 | 2-8 | C. Dahle 16 | C. Dahle 5 | L. Larry 8 |
| December 30, 2027 | @ Drake Bulldogs* | W 82-67 | 3-8 | O. Fogel 21 | C. Dahle 7 | O. Fogel 7 |
| January 2, 2028 | EVANSVILLE PURPLE ACES* | W 91-64 | 4-8 | M. Edgerson 20 | C. Dahle 5 | M. Edgerson 10 |
| January 4, 2028 | INDIANA STATE SYCAMORES* | W 88-81 | 5-8 | G. Christiansen 18 | C. Dahle 7 | M. Edgerson 10 |
| January 6, 2028 | @ Southern Illinois Salukis* | W 69-61 | 6-8 | O. Fogel 13 | C. Dahle 5 | D. Mitchell 9 |
| January 11, 2028 | BELMONT BRUINS* | W 73-67 | 7-8 | D. Mitchell 19 | C. Dahle 4 | C. Dahle 6 |
| January 13, 2028 | @ Murray State Racers* | W 85-69 | 8-8 | T. Jacobs 20 | C. Dahle 6 | M. Edgerson 9 |
| January 18, 2028 | ILLINOIS-CHICAGO FLAMES* | W 81-71 | 9-8 | O. Fogel 16 | C. Dahle 11 | D. Mitchell 8 |
| January 20, 2028 | NORTHERN IOWA PANTHERS* | W 104-94 OT | 10-8 | D. Mitchell 23 | C. Dahle 8 | M. Edgerson 12 |
| January 25, 2028 | @ Bradley Braves* | L 64-78 | 10-9 | D. Mitchell 17 | C. Dahle 4 | D. Mitchell 11 |
| January 27, 2028 | @ Indiana State Sycamores* | L 56-60 | 10-10 | M. Edgerson 13 | C. Dahle 3 | M. Edgerson 11 |
| February 1, 2028 | SOUTHERN ILLINOIS SALUKIS* | L 97-109 | 10-11 | M. Edgerson 15 | S. Scott 6 | M. Edgerson 9 |
| February 3, 2028 | DRAKE BULLDOGS* | W 85-79 | 11-11 | O. Fogel 18 | G. Christiansen 5 | M. Edgerson 9 |
| February 8, 2028 | @ Northern Iowa Panthers* | L 95-104 OT | 11-12 | D. Mitchell 26 | C. Dahle 5 | M. Edgerson 9 |
| February 10, 2028 | @ Illinois-Chicago Flames* | L 59-79 | 11-13 | C. Dahle 14 | C. Dahle 4 | D. Mitchell 6 |
| February 17, 2028 | BRADLEY BRAVES* | W 78-68 | 12-13 | M. Edgerson 17 | C. Dahle 6 | D. Mitchell 10 |
| February 22, 2028 | MURRAY STATE RACERS* | W 73-69 | 13-13 | T. Jacobs 17 | C. Dahle 6 | M. Edgerson 9 |
| February 27, 2028 | @ Belmont Bruins* | L 79-94 | 13-14 | G. Christiansen 21 | C. Dahle 4 | D. Mitchell 5 |
| March 1, 2028 | @ Illinois State Redbirds* | L 65-85 | 13-15 | D. Mitchell 19 | S. Scott 4 | D. Mitchell 10 |
| March 3, 2028 | @ Evansville Purple Aces* | W 91-73 | 14-15 | D. Mitchell 19 | C. Dahle 6 | T. Jacobs 5 |
| March 7, 2028 | @ Illinois State Redbirds (18-11, 12-3 Home) MVC Tournament | - | | | | |
