| November 16, 2027 | @ Ohio State Buckeyes | L 60-80 | 0-1 | E. Grundy 15 | J. Mihm 3 | E. Grundy 7 |
| November 17, 2027 | @ Eastern Washington Eagles | L 80-86 | 0-2 | E. Grundy 17 | G. Pryor 4 | K. Jackson 8 |
| November 22, 2027 | @ Central Arkansas Bears | L 59-79 | 0-3 | E. Grundy 14 | J. Mihm 7 | T. Warren 9 |
| November 24, 2027 | @ #19 Texas Tech Red Raiders | L 53-59 | 0-4 | T. Warren 14 | J. Mihm 4 | T. Warren 9 |
| November 29, 2027 | @ Cal St. Bakersfield Roadrunners | L 87-91 | 0-5 | E. Grundy 20 | J. Mihm 8 | K. Jackson 5 |
| December 3, 2027 | TEXAS-SAN ANTONIO ROADRUNNERS | W 79-71 | 1-5 | T. Warren 17 | J. Mihm 6 | E. Grundy 9 |
| December 10, 2027 | OMAHA MAVERICKS | W 85-69 | 2-5 | E. Grundy 23 | T. Warren 6 | O. Thompson 8 |
| December 12, 2027 | @ Morgan State Bears | L 71-84 | 2-6 | E. Grundy 20 | J. Mihm 4 | E. Grundy 6 |
| December 17, 2027 | HAMPTON PIRATES | L 75-80 | 2-7 | E. Grundy 17 | J. Mihm 6 | S. Smith 7 |
| December 20, 2027 | BINGHAMTON BEARCATS | W 84-77 | 3-7 | G. Pryor 18 | G. Pryor 7 | S. Smith 6 |
| December 27, 2027 | @ Dayton Flyers | L 51-73 | 3-8 | E. Grundy 18 | J. Mihm 5 | O. Thompson 6 |
| January 2, 2028 | LINDENWOOD LIONS* | L 72-75 | 3-9 | O. Thompson 20 | S. Wilkes 4 | T. Warren 8 |
| January 6, 2028 | @ SIU Edwardsville Cougars* | W 91-80 | 4-9 | E. Grundy 20 | J. Mihm 4 | O. Thompson 10 |
| January 11, 2028 | SOUTHERN INDIANA SCREAMING EAGLES* | W 102-81 | 5-9 | E. Grundy 21 | J. Mihm 7 | K. Jackson 5 |
| January 13, 2028 | @ Eastern Illinois Panthers* | L 65-72 | 5-10 | E. Grundy 14 | J. Mihm 7 | O. Thompson 7 |
| January 16, 2028 | @ Lindenwood Lions* | L 76-89 | 5-11 | E. Grundy 20 | J. Mihm 5 | E. Grundy 9 |
| January 18, 2028 | WESTERN ILLINOIS LEATHERNECKS* | W 73-45 | 6-11 | K. Jackson 15 | J. Mihm 8 | S. Smith 8 |
| January 20, 2028 | SIU EDWARDSVILLE COUGARS* | L 67-78 | 6-12 | E. Grundy 16 | J. Mihm 5 | T. Warren 10 |
| January 23, 2028 | @ Tennessee Tech Golden Eagles* | W 75-62 | 7-12 | E. Grundy 18 | E. Grundy 6 | E. Grundy 7 |
| January 27, 2028 | TENNESSEE STATE TIGERS* | W 82-70 | 8-12 | G. Pryor 19 | J. Mihm 7 | J. Mihm 8 |
| February 1, 2028 | @ SE Missouri State Redhawks* | L 63-71 | 8-13 | S. Wilkes 12 | J. Mihm 5 | O. Thompson 8 |
| February 3, 2028 | @ Morehead State Eagles* | W 83-77 | 9-13 | E. Grundy 21 | J. Mihm 6 | T. Warren 8 |
| February 6, 2028 | @ Tennessee State Tigers* | W 78-77 | 10-13 | E. Grundy 17 | J. Mihm 8 | T. Warren 7 |
| February 10, 2028 | LITTLE ROCK TROJANS* | W 75-71 | 11-13 | J. Mihm 14 | J. Mihm 5 | E. Grundy 7 |
| February 13, 2028 | SE MISSOURI STATE REDHAWKS* | L 72-79 | 11-14 | S. Wilkes 18 | J. Mihm 4 | S. Smith 5 |
| February 15, 2028 | @ Western Illinois Leathernecks* | L 70-73 | 11-15 | T. Warren 12 | J. Mihm 5 | G. Pryor 6 |
| February 20, 2028 | @ Southern Indiana Screaming Eagles* | W 89-72 | 12-15 | G. Pryor 15 | J. Mihm 8 | T. Warren 6 |
| February 22, 2028 | TENNESSEE TECH GOLDEN EAGLES* | W 96-75 | 13-15 | E. Grundy 30 | J. Grimes 6 | G. Pryor 6 |
| March 1, 2028 | MOREHEAD STATE EAGLES* | W 88-72 | 14-15 | E. Grundy 20 | J. Mihm 8 | O. Thompson 9 |
| March 6, 2028 | TBD OVC Tournament | - | | | | |
