| November 14, 2027 | CAL ST. NORTHRIDGE MATADORS | W 98-70 | 1-0 | K. Sharp 32 | S. Chambers 7 | J. Odle 8 |
| November 17, 2027 | VA COMMONWEALTH RAMS | L 68-81 | 1-1 | J. Odle 19 | T. Sykes 3 | M. Slocum 12 |
| November 25, 2027 | @ #5 Duke Blue Devils | L 72-79 | 1-2 | J. Odle 16 | S. Chambers 5 | B. Weaver 9 |
| December 2, 2027 | @ Maryland Terrapins | L 66-72 | 1-3 | K. Sharp 13 | T. Sykes 5 | M. Slocum 11 |
| December 7, 2027 | MONTANA STATE BOBCATS | W 105-69 | 2-3 | K. Sharp 21 | D. McIntosh 6 | J. Murphy 5 |
| December 8, 2027 | MD-BALTIMORE COUNTY RETRIEVERS | W 75-61 | 3-3 | J. Odle 19 | S. Chambers 3 | J. Murphy 8 |
| December 13, 2027 | BRIGHAM YOUNG COUGARS* | L 63-81 | 3-4 | K. Sharp 15 | B. Weaver 7 | B. Weaver 8 |
| December 19, 2027 | SAINT LOUIS BILLIKENS | W 82-60 | 4-4 | J. Odle 19 | S. Chambers 6 | J. Murphy 12 |
| December 23, 2027 | FRESNO STATE BULLDOGS JAG Holiday Invitational | L 82-85 | 4-5 | J. Murphy 15 | K. Sharp 5 | B. Weaver 9 |
| December 26, 2027 | #1 KANSAS JAYHAWKS* | L 57-75 | 4-6 | B. Michaels 10 | D. McIntosh 4 | B. Weaver 5 |
| December 30, 2027 | @ #4 West Virginia Mountaineers* | L 75-93 | 4-7 | J. Odle 19 | S. Chambers 2 | J. Murphy 8 |
| January 4, 2028 | BRIGHAM YOUNG COUGARS* | L 75-78 | 4-8 | J. Odle 13 | S. Chambers 3 | M. Slocum 9 |
| January 6, 2028 | @ Texas Christian Horned Frogs* | W 90-82 | 5-8 | K. Sharp 19 | J. Murphy 7 | B. Weaver 6 |
| January 9, 2028 | @ Houston Cougars* | L 93-97 | 5-9 | S. Chambers 16 | S. Chambers 6 | M. Slocum 8 |
| January 13, 2028 | COLORADO BUFFALOES* | W 96-75 | 6-9 | K. Sharp 20 | S. Chambers 3 | M. Slocum 9 |
| January 18, 2028 | #10 CINCINNATI BEARCATS* | L 88-101 | 6-10 | B. Michaels 16 | S. Chambers 6 | J. Odle 6 |
| January 23, 2028 | @ Central Florida Knights* | W 74-66 | 7-10 | K. Sharp 19 | S. Chambers 4 | M. Slocum 12 |
| January 25, 2028 | @ Brigham Young Cougars* | L 76-84 | 7-11 | K. Sharp 19 | M. Slocum 4 | M. Slocum 10 |
| January 27, 2028 | TEXAS CHRISTIAN HORNED FROGS* | W 87-73 | 8-11 | B. Michaels 20 | S. Chambers 6 | B. Michaels 5 |
| February 1, 2028 | @ #5 Kansas Jayhawks* | L 68-82 | 8-12 | D. McIntosh 12 | T. Sykes 4 | M. Slocum 7 |
| February 6, 2028 | #18 OKLAHOMA STATE COWBOYS* | W 78-60 | 9-12 | K. Sharp 19 | D. McIntosh 4 | M. Slocum 13 |
| February 8, 2028 | @ Iowa State Cyclones* | L 69-82 | 9-13 | K. Sharp 19 | S. Chambers 5 | M. Slocum 9 |
| February 10, 2028 | CENTRAL FLORIDA KNIGHTS* | W 79-71 | 10-13 | K. Sharp 20 | S. Chambers 5 | M. Slocum 9 |
| February 15, 2028 | #6 ARIZONA WILDCATS* | L 74-97 | 10-14 | J. Murphy 21 | K. Sharp 4 | J. Odle 9 |
| February 17, 2028 | @ Arizona State Sun Devils* | L 72-76 | 10-15 | J. Odle 20 | S. Chambers 3 | J. Odle 11 |
| February 22, 2028 | KANSAS STATE WILDCATS* | W 80-73 | 11-15 | K. Sharp 15 | K. Sharp 5 | J. Odle 10 |
| February 24, 2028 | @ Baylor Bears* | W 82-70 | 12-15 | J. Odle 19 | B. Michaels 5 | J. Odle 11 |
| March 1, 2028 | @ #6 Arizona Wildcats* | L 68-83 | 12-16 | J. Murphy 10 | J. Odle 3 | B. Weaver 9 |
| March 3, 2028 | TEXAS TECH RED RAIDERS* | L 63-79 | 12-17 | K. Sharp 14 | K. Sharp 2 | J. Odle 5 |
| March 8, 2028 | CENTRAL FLORIDA KNIGHTS Big 12 Tournament | W 74-67 | 13-17 | K. Sharp 16 | S. Chambers 3 | B. Weaver 13 |
| March 9, 2028 | @ #13 Cincinnati Bearcats Big 12 Tournament | W 83-73 | 14-17 | S. Chambers 14 | D. McIntosh 5 | M. Slocum 8 |
| March 10, 2028 | @ #5 Kansas Jayhawks Big 12 Tournament | L 58-76 | 14-18 | K. Sharp 11 | S. Chambers 2 | B. Weaver 5 |
