| November 18, 2027 | @ Western Michigan Broncos | L 64-78 | 0-1 | D. Few 14 | S. Mitchell 7 | D. Few 5 |
| November 23, 2027 | @ Nebraska Cornhuskers | L 68-79 | 0-2 | J. Shueller 18 | S. Mitchell 6 | K. Hodge 9 |
| November 26, 2027 | NORTHEASTERN HUSKIES | W 87-69 | 1-2 | D. Few 22 | S. Mitchell 5 | D. Few 6 |
| November 30, 2027 | DARTMOUTH BIG GREEN | W 93-64 | 2-2 | S. Mitchell 22 | S. Mitchell 6 | D. Few 8 |
| December 3, 2027 | @ Brown Bears | L 68-80 | 2-3 | D. Few 16 | J. Newman 5 | J. Shueller 5 |
| December 5, 2027 | @ #9 Iowa State Cyclones | L 56-96 | 2-4 | D. Few 16 | S. Mitchell 2 | K. Hodge 6 |
| December 9, 2027 | IU (INDY) JAGUARS | W 83-60 | 3-4 | J. Shueller 24 | S. Mitchell 7 | T. Franklin 8 |
| December 13, 2027 | @ Dayton Flyers | L 61-69 | 3-5 | J. Shueller 16 | S. Mitchell 7 | J. Shueller 6 |
| December 16, 2027 | @ Texas-El Paso Miners Battle 4 Atlantis | W 63-44 | 4-5 | T. Franklin 14 | S. Mitchell 4 | J. Shueller 7 |
| December 17, 2027 | @ Florida Gulf Coast Eagles Battle 4 Atlantis | W 85-77 | 5-5 | D. Few 23 | S. Mitchell 6 | S. Mitchell 6 |
| December 18, 2027 | #23 VANDERBILT COMMODORES Battle 4 Atlantis | L 68-84 | 5-6 | D. Few 14 | S. Mitchell 3 | K. Hodge 5 |
| December 27, 2027 | BOWLING GREEN STATE FALCONS | L 74-81 | 5-7 | D. Few 23 | S. Mitchell 3 | T. Franklin 8 |
| December 29, 2027 | DELAWARE STATE HORNETS | W 87-74 | 6-7 | D. Few 22 | S. Mitchell 5 | J. Shueller 6 |
| January 2, 2028 | FLORIDA ATLANTIC OWLS* | L 59-73 | 6-8 | S. Mitchell 21 | J. Shueller 4 | K. Hodge 6 |
| January 5, 2028 | NORTH TEXAS MEAN GREEN* | W 93-82 | 7-8 | D. Few 21 | T. Franklin 6 | K. Hodge 11 |
| January 9, 2028 | @ East Carolina Pirates* | W 77-72 | 8-8 | S. Mitchell 17 | S. Mitchell 5 | S. Mitchell 6 |
| January 12, 2028 | @ Tulsa Golden Hurricanes* | L 80-90 | 8-9 | J. Shueller 32 | S. Mitchell 8 | T. Franklin 11 |
| January 14, 2028 | @ Memphis Tigers* | L 82-84 | 8-10 | D. Few 14 | S. Mitchell 5 | J. Shueller 7 |
| January 16, 2028 | CHARLOTTE 49ERS* | W 79-68 | 9-10 | S. Mitchell 16 | S. Mitchell 4 | K. Hodge 9 |
| January 19, 2028 | @ Alabama-Birmingham Blazers* | L 95-104 | 9-11 | J. Shueller 30 | S. Mitchell 9 | T. Franklin 9 |
| January 23, 2028 | #24 MEMPHIS TIGERS* | L 81-88 | 9-12 | D. Few 20 | S. Mitchell 4 | J. Shueller 7 |
| January 26, 2028 | @ Florida Atlantic Owls* | L 67-78 | 9-13 | D. Few 18 | S. Mitchell 4 | T. Franklin 8 |
| January 30, 2028 | @ Rice Owls* | L 52-68 | 9-14 | T. Franklin 12 | S. Mitchell 3 | J. Shueller 9 |
| February 6, 2028 | TEXAS-SAN ANTONIO ROADRUNNERS* | W 74-60 | 10-14 | D. Few 13 | S. Mitchell 3 | K. Hodge 9 |
| February 9, 2028 | @ Tulane Green Wave* | L 68-82 | 10-15 | T. Franklin 16 | S. Mitchell 6 | T. Franklin 11 |
| February 13, 2028 | @ #23 Wichita State Shockers* | L 59-72 | 10-16 | D. Few 16 | S. Mitchell 3 | T. Franklin 8 |
| February 16, 2028 | TEMPLE OWLS* | L 69-76 | 10-17 | J. Newman 13 | M. Babcock 3 | K. Hodge 9 |
| February 20, 2028 | TULSA GOLDEN HURRICANES* | W 83-75 | 11-17 | S. Mitchell 27 | S. Mitchell 7 | T. Franklin 11 |
| February 23, 2028 | ALABAMA-BIRMINGHAM BLAZERS* | L 73-81 | 11-18 | S. Mitchell 18 | S. Mitchell 6 | S. Mitchell 5 |
| February 27, 2028 | EAST CAROLINA PIRATES* | W 74-55 | 12-18 | S. Mitchell 15 | S. Mitchell 4 | T. Franklin 8 |
| March 2, 2028 | @ Charlotte 49ers* | L 75-86 | 12-19 | S. Mitchell 18 | D. Few 4 | S. Mitchell 6 |
| March 7, 2028 | @ Charlotte 49ers (13-16, 11-4 Home) AAC Tournament | - | | | | |
