| November 19, 2027 | PRINCETON TIGERS | W 80-68 | 1-0 | G. Alston 21 | E. Roberson 7 | D. Temple 7 |
| November 23, 2027 | @ #9 Louisville Cardinals | L 68-90 | 1-1 | C. Benjamin 29 | G. Alston 4 | E. Roberson 8 |
| November 26, 2027 | COASTAL CAROLINA CHANTICLEERS | W 94-64 | 2-1 | D. Temple 17 | E. Roberson 5 | D. Temple 10 |
| November 29, 2027 | CENTRAL MICHIGAN CHIPPEWAS | W 82-77 | 3-1 | G. Alston 19 | G. Alston 5 | G. Alston 6 |
| December 2, 2027 | LONGWOOD LANCERS | W 82-75 | 4-1 | C. Benjamin 16 | J. Jack 5 | D. Temple 10 |
| December 14, 2027 | SOUTH DAKOTA COYOTES | W 78-71 | 5-1 | E. Roberson 12 | D. Denson 6 | E. Roberson 8 |
| December 16, 2027 | BINGHAMTON BEARCATS | W 93-64 | 6-1 | E. Roberson 16 | E. Roberson 5 | E. Roberson 15 |
| December 19, 2027 | BAYLOR BEARS | L 76-89 | 6-2 | G. Alston 15 | G. Alston 4 | D. Temple 8 |
| December 23, 2027 | CALIFORNIA BAPTIST LANCERS JAG Holiday Invitational | L 57-86 | 6-3 | C. Benjamin 13 | J. Jack 3 | E. Roberson 10 |
| December 26, 2027 | MARYLAND TERRAPINS* | W 78-67 | 7-3 | G. Alston 17 | G. Alston 5 | E. Roberson 10 |
| December 28, 2027 | @ Iowa Hawkeyes* | L 85-94 | 7-4 | C. Benjamin 23 | G. Alston 7 | C. Benjamin 8 |
| January 2, 2028 | ILLINOIS FIGHTING ILLINI* | W 107-93 | 8-4 | T. Jordan 21 | G. Alston 6 | C. Moore 9 |
| January 4, 2028 | MINNESOTA GOLDEN GOPHERS* | L 102-109 | 8-5 | C. Benjamin 22 | G. Alston 5 | E. Roberson 10 |
| January 9, 2028 | @ Penn State Nittany Lions* | W 78-73 | 9-5 | D. Temple 17 | G. Alston 8 | J. Ross 7 |
| January 11, 2028 | @ Indiana Hoosiers* | W 72-70 | 10-5 | G. Alston 13 | E. Roberson 5 | C. Benjamin 7 |
| January 16, 2028 | WASHINGTON HUSKIES* | L 69-76 | 10-6 | C. Benjamin 23 | G. Alston 7 | J. Ross 9 |
| January 18, 2028 | @ Nebraska Cornhuskers* | L 71-82 | 10-7 | C. Benjamin 14 | G. Alston 6 | J. Ross 9 |
| January 23, 2028 | OHIO STATE BUCKEYES* | L 70-78 | 10-8 | J. Ross 20 | G. Alston 4 | C. Benjamin 5 |
| January 25, 2028 | @ Rutgers Scarlet Knights* | L 73-82 | 10-9 | G. Alston 18 | G. Alston 3 | E. Roberson 6 |
| January 30, 2028 | #5 WISCONSIN BADGERS* | L 76-88 | 10-10 | G. Alston 17 | G. Alston 4 | E. Roberson 7 |
| February 1, 2028 | #2 MICHIGAN STATE SPARTANS* | L 82-84 OT | 10-11 | J. Ross 13 | C. Benjamin 6 | J. Ross 10 |
| February 6, 2028 | @ Northwestern Wildcats* | W 86-75 | 11-11 | G. Alston 24 | G. Alston 5 | E. Roberson 9 |
| February 8, 2028 | #24 UCLA BRUINS* | W 75-69 | 12-11 | J. Ross 18 | G. Alston 7 | E. Roberson 8 |
| February 13, 2028 | @ #21 Oregon Ducks* | W 103-100 | 13-11 | C. Benjamin 21 | G. Alston 7 | J. Jack 6 |
| February 15, 2028 | MICHIGAN WOLVERINES* | W 92-89 | 14-11 | E. Roberson 24 | G. Alston 11 | E. Roberson 10 |
| February 20, 2028 | @ #14 Purdue Boilermakers* | L 66-77 | 14-12 | D. Temple 15 | G. Alston 4 | J. Ross 8 |
| February 22, 2028 | @ UCLA Bruins* | L 57-73 | 14-13 | G. Alston 10 | G. Alston 6 | D. Temple 7 |
| February 27, 2028 | RUTGERS SCARLET KNIGHTS* | L 73-86 | 14-14 | J. Ross 15 | G. Alston 4 | E. Roberson 10 |
| March 1, 2028 | @ Illinois Fighting Illini* | L 89-96 | 14-15 | C. Benjamin 19 | D. Temple 4 | J. Ross 8 |
| March 8, 2028 | @ Minnesota Golden Gophers (16-13, 14-3 Home) Big 10 Tournament | - | | | | |
