| November 15, 2027 | SOUTHERN JAGUARS | L 62-69 | 0-1 | J. Whitmore 19 | C. Wormley 5 | J. Whitmore 9 |
| November 18, 2027 | MIAMI (FL) HURRICANES | W 86-62 | 1-1 | D. Kowalski 14 | K. Arnold 4 | J. Yearwood 12 |
| November 22, 2027 | MISSISSIPPI VALLEY DELTA DEVILS | W 79-69 | 2-1 | M. Land 22 | D. Kowalski 4 | M. Land 7 |
| November 26, 2027 | FLORIDA GULF COAST EAGLES | W 82-65 | 3-1 | C. Wormley 19 | J. Whitmore 3 | J. Whitmore 7 |
| November 29, 2027 | #4 VIRGINIA CAVALIERS | W 63-59 | 4-1 | D. Kowalski 15 | D. Kowalski 5 | J. Whitmore 9 |
| December 2, 2027 | DREXEL DRAGONS | W 90-84 | 5-1 | J. Emerson 16 | P. Bryant 6 | J. Whitmore 6 |
| December 6, 2027 | @ Vanderbilt Commodores | W 60-47 | 6-1 | M. Land 11 | J. Emerson 4 | J. Whitmore 12 |
| December 9, 2027 | WOFFORD TERRIERS Cayman Islands Classic | W 71-66 | 7-1 | J. Whitmore 16 | P. Bryant 5 | M. Land 11 |
| December 10, 2027 | LOYOLA (IL) RAMBLERS Cayman Islands Classic | W 85-83 | 8-1 | J. Whitmore 15 | P. Bryant 7 | J. Yearwood 7 |
| December 11, 2027 | GEORGIA TECH YELLOW JACKETS Cayman Islands Classic | L 52-68 | 8-2 | J. Whitmore 12 | P. Bryant 2 | J. Whitmore 10 |
| December 19, 2027 | BINGHAMTON BEARCATS (6-4, 4-3 Away) | - | | | | |
| December 26, 2027 | ILLINOIS FIGHTING ILLINI (6-3, 0-0, 0-1 Away)* | - | | | | |
| December 28, 2027 | @ Iowa Hawkeyes (3-5, 0-0, 3-2 Home)* | - | | | | |
| January 2, 2028 | @ Maryland Terrapins (6-2, 0-0, 5-0 Home)* | - | | | | |
| January 4, 2028 | PENN STATE NITTANY LIONS (3-4, 0-0, 0-1 Away)* | - | | | | |
| January 9, 2028 | NEBRASKA CORNHUSKERS (4-4, 0-0, 0-1 Away)* | - | | | | |
| January 11, 2028 | WISCONSIN BADGERS (6-2, 0-0, 1-1 Away)* | - | | | | |
| January 16, 2028 | SOUTHERN CALIFORNIA TROJANS (5-3, 0-0, 0-0 Away)* | - | | | | |
| January 18, 2028 | @ Oregon Ducks (4-5, 0-0, 3-3 Home)* | - | | | | |
| January 23, 2028 | MICHIGAN STATE SPARTANS (6-1, 0-0, 1-1 Away)* | - | | | | |
| January 25, 2028 | @ Indiana Hoosiers (4-4, 0-0, 3-1 Home)* | - | | | | |
| January 30, 2028 | NORTHWESTERN WILDCATS (5-3, 0-0, 0-1 Away)* | - | | | | |
| February 1, 2028 | @ Minnesota Golden Gophers (7-3, 0-0, 5-0 Home)* | - | | | | |
| February 6, 2028 | OHIO STATE BUCKEYES (6-3, 0-0, 1-2 Away)* | - | | | | |
| February 8, 2028 | @ Washington Huskies (5-3, 0-0, 5-2 Home)* | - | | | | |
| February 13, 2028 | @ Rutgers Scarlet Knights (5-4, 0-0, 4-2 Home)* | - | | | | |
| February 15, 2028 | @ Michigan Wolverines (10-0, 0-0, 7-0 Home)* | - | | | | |
| February 20, 2028 | @ Purdue Boilermakers (6-3, 0-0, 5-2 Home)* | - | | | | |
| February 22, 2028 | WASHINGTON HUSKIES (5-3, 0-0, 0-0 Away)* | - | | | | |
| February 27, 2028 | @ Penn State Nittany Lions (3-4, 0-0, 3-3 Home)* | - | | | | |
| March 1, 2028 | MINNESOTA GOLDEN GOPHERS (7-3, 0-0, 0-2 Away)* | - | | | | |
