| November 15, 2027 | SOUTHERN JAGUARS | L 62-69 | 0-1 | J. Whitmore 19 | C. Wormley 5 | J. Whitmore 9 |
| November 18, 2027 | MIAMI (FL) HURRICANES | W 86-62 | 1-1 | D. Kowalski 14 | K. Arnold 4 | J. Yearwood 12 |
| November 22, 2027 | MISSISSIPPI VALLEY DELTA DEVILS | W 79-69 | 2-1 | M. Land 22 | D. Kowalski 4 | M. Land 7 |
| November 26, 2027 | FLORIDA GULF COAST EAGLES | W 82-65 | 3-1 | C. Wormley 19 | J. Whitmore 3 | J. Whitmore 7 |
| November 29, 2027 | #4 VIRGINIA CAVALIERS | W 63-59 | 4-1 | D. Kowalski 15 | D. Kowalski 5 | J. Whitmore 9 |
| December 2, 2027 | DREXEL DRAGONS | W 90-84 | 5-1 | J. Emerson 16 | P. Bryant 6 | J. Whitmore 6 |
| December 6, 2027 | @ Vanderbilt Commodores | W 60-47 | 6-1 | M. Land 11 | J. Emerson 4 | J. Whitmore 12 |
| December 9, 2027 | WOFFORD TERRIERS Cayman Islands Classic | W 71-66 | 7-1 | J. Whitmore 16 | P. Bryant 5 | M. Land 11 |
| December 10, 2027 | LOYOLA (IL) RAMBLERS Cayman Islands Classic | W 85-83 | 8-1 | J. Whitmore 15 | P. Bryant 7 | J. Yearwood 7 |
| December 11, 2027 | GEORGIA TECH YELLOW JACKETS Cayman Islands Classic | L 52-68 | 8-2 | J. Whitmore 12 | P. Bryant 2 | J. Whitmore 10 |
| December 19, 2027 | BINGHAMTON BEARCATS | W 69-66 | 9-2 | J. Whitmore 15 | C. Wormley 7 | J. Whitmore 8 |
| December 26, 2027 | ILLINOIS FIGHTING ILLINI* | L 53-72 | 9-3 | J. Whitmore 12 | C. Wormley 4 | K. Arnold 11 |
| December 28, 2027 | @ Iowa Hawkeyes* | W 81-74 | 10-3 | P. Bryant 17 | P. Bryant 4 | J. Whitmore 6 |
| January 2, 2028 | @ #15 Maryland Terrapins* | L 69-75 | 10-4 | M. Land 12 | P. Bryant 7 | J. Whitmore 8 |
| January 4, 2028 | PENN STATE NITTANY LIONS* | L 65-78 | 10-5 | C. Wormley 14 | P. Bryant 5 | M. Land 8 |
| January 9, 2028 | NEBRASKA CORNHUSKERS* | W 87-75 | 11-5 | J. Whitmore 22 | P. Bryant 10 | J. Yearwood 7 |
| January 11, 2028 | #18 WISCONSIN BADGERS* | W 82-70 | 12-5 | P. Bryant 13 | P. Bryant 4 | K. Arnold 6 |
| January 16, 2028 | SOUTHERN CALIFORNIA TROJANS* | W 78-57 | 13-5 | J. Whitmore 16 | C. Wormley 5 | M. Land 7 |
| January 18, 2028 | @ Oregon Ducks* | L 55-92 | 13-6 | C. Wormley 15 | D. Kowalski 4 | J. Yearwood 10 |
| January 23, 2028 | #21 MICHIGAN STATE SPARTANS* | W 78-61 | 14-6 | J. Whitmore 17 | D. Kowalski 5 | M. Land 8 |
| January 25, 2028 | @ Indiana Hoosiers* | W 70-66 | 15-6 | M. Land 18 | C. Wormley 3 | P. Bryant 6 |
| January 30, 2028 | NORTHWESTERN WILDCATS* | L 52-59 | 15-7 | J. Whitmore 18 | D. Kowalski 3 | J. Whitmore 6 |
| February 1, 2028 | @ Minnesota Golden Gophers* | L 64-72 | 15-8 | M. Land 15 | J. Yearwood 3 | J. Whitmore 9 |
| February 6, 2028 | OHIO STATE BUCKEYES* | L 70-78 | 15-9 | M. Land 13 | D. Kowalski 3 | J. Whitmore 7 |
| February 8, 2028 | @ Washington Huskies* | L 51-82 | 15-10 | D. Kowalski 20 | J. Whitmore 3 | J. Whitmore 9 |
| February 13, 2028 | @ Rutgers Scarlet Knights* | W 77-71 | 16-10 | J. Whitmore 15 | J. Emerson 3 | J. Whitmore 9 |
| February 15, 2028 | @ #3 Michigan Wolverines* | L 60-77 | 16-11 | J. Whitmore 14 | D. Kowalski 4 | J. Whitmore 6 |
| February 20, 2028 | @ Purdue Boilermakers* | L 65-76 | 16-12 | M. Land 13 | D. Kowalski 2 | J. Yearwood 8 |
| February 22, 2028 | WASHINGTON HUSKIES* | W 74-59 | 17-12 | C. Wormley 18 | J. Whitmore 4 | J. Whitmore 11 |
| February 27, 2028 | @ Penn State Nittany Lions* | L 59-66 | 17-13 | J. Whitmore 14 | D. Kowalski 3 | D. Kowalski 7 |
| March 1, 2028 | MINNESOTA GOLDEN GOPHERS* | L 61-69 | 17-14 | J. Whitmore 13 | M. Land 4 | J. Whitmore 9 |
| March 8, 2028 | @ Washington Huskies Big 10 Tournament | L 56-64 | 17-15 | K. Arnold 10 | C. Wormley 2 | K. Arnold 9 |
