| November 15, 2027 | MD-BALTIMORE COUNTY RETRIEVERS | W 89-73 | 1-0 | J. Durden 26 | J. Durden 6 | T. Holmes 9 |
| November 17, 2027 | NORTHERN COLORADO BEARS | W 62-49 | 2-0 | J. Durden 21 | K. Porter 3 | T. Holmes 6 |
| November 26, 2027 | GEORGIA TECH YELLOW JACKETS | W 87-69 | 3-0 | J. Durden 20 | R. Stevens 4 | J. Durden 11 |
| November 28, 2027 | #9 IOWA STATE CYCLONES | L 72-75 | 3-1 | R. Blackshear 16 | J. Durden 5 | J. Durden 10 |
| December 1, 2027 | PORTLAND STATE VIKINGS | L 60-68 | 3-2 | T. Holmes 13 | R. Blackshear 3 | B. Caspers 9 |
| December 6, 2027 | MIAMI (OH) REDHAWKS | W 87-70 | 4-2 | J. Durden 32 | K. Porter 4 | T. Holmes 8 |
| December 9, 2027 | EAST TENNESSEE STATE BUCCANEERS Jimmy V Classic | W 71-67 | 5-2 | R. Blackshear 12 | B. Caspers 4 | B. Caspers 7 |
| December 10, 2027 | UTAH UTES Jimmy V Classic | L 58-76 | 5-3 | J. Durden 22 | K. Porter 2 | J. Durden 12 |
| December 16, 2027 | KENT STATE GOLDEN FLASHES | W 98-66 | 6-3 | R. Blackshear 19 | K. Porter 5 | J. Bond 7 |
| December 23, 2027 | WESTERN MICHIGAN BRONCOS | W 92-68 | 7-3 | R. Blackshear 20 | B. Caspers 5 | T. Holmes 6 |
| December 26, 2027 | #13 PURDUE BOILERMAKERS* | W 94-76 | 8-3 | J. Durden 21 | B. Caspers 9 | B. Caspers 8 |
| December 28, 2027 | PENN STATE NITTANY LIONS* | W 82-64 | 9-3 | R. Blackshear 19 | K. Porter 5 | T. Holmes 10 |
| January 2, 2028 | NEBRASKA CORNHUSKERS* | W 89-79 | 10-3 | J. Durden 33 | B. Caspers 6 | J. Durden 11 |
| January 4, 2028 | IOWA HAWKEYES* | W 92-70 | 11-3 | J. Durden 23 | B. Caspers 10 | R. Blackshear 11 |
| January 9, 2028 | @ Indiana Hoosiers* | W 95-71 | 12-3 | J. Durden 25 | B. Caspers 7 | T. Holmes 8 |
| January 11, 2028 | MARYLAND TERRAPINS* | W 86-72 | 13-3 | R. Blackshear 17 | B. Caspers 6 | J. Durden 7 |
| January 16, 2028 | @ #5 Wisconsin Badgers* | L 65-83 | 13-4 | R. Blackshear 15 | B. Caspers 4 | R. Blackshear 7 |
| January 18, 2028 | @ Ohio State Buckeyes* | W 75-65 | 14-4 | R. Blackshear 18 | B. Caspers 5 | T. Holmes 9 |
| January 23, 2028 | WASHINGTON HUSKIES* | W 90-79 | 15-4 | J. Durden 22 | B. Caspers 10 | B. Caspers 9 |
| January 25, 2028 | #3 MICHIGAN STATE SPARTANS* | L 90-100 | 15-5 | T. Holmes 26 | B. Caspers 9 | T. Holmes 8 |
| January 30, 2028 | @ Northwestern Wildcats* | W 84-66 | 16-5 | J. Durden 27 | B. Caspers 10 | T. Holmes 9 |
| February 1, 2028 | RUTGERS SCARLET KNIGHTS* | W 71-67 | 17-5 | R. Blackshear 17 | K. Porter 3 | B. Caspers 11 |
| February 6, 2028 | @ #21 Oregon Ducks* | L 82-85 | 17-6 | B. Caspers 15 | B. Caspers 6 | J. Durden 8 |
| February 8, 2028 | @ Southern California Trojans* | L 69-75 | 17-7 | R. Blackshear 17 | T. Holmes 4 | T. Holmes 11 |
| February 13, 2028 | @ Minnesota Golden Gophers* | L 67-73 | 17-8 | R. Blackshear 20 | B. Caspers 5 | J. Durden 6 |
| February 15, 2028 | ILLINOIS FIGHTING ILLINI* | L 83-87 | 17-9 | J. Durden 31 | B. Caspers 4 | B. Caspers 5 |
| February 20, 2028 | @ Michigan Wolverines* | L 80-102 | 17-10 | B. Caspers 13 | B. Caspers 3 | B. Caspers 7 |
| February 22, 2028 | SOUTHERN CALIFORNIA TROJANS* | W 73-57 | 18-10 | R. Blackshear 20 | J. Durden 3 | J. Bond 16 |
| February 27, 2028 | @ Maryland Terrapins* | W 77-73 | 19-10 | J. Durden 19 | K. Porter 4 | B. Caspers 12 |
| March 1, 2028 | @ Rutgers Scarlet Knights* | L 77-90 | 19-11 | J. Durden 20 | K. Porter 6 | B. Caspers 11 |
| March 10, 2028 | TBD Big 10 Tournament | - | | | | |
