| November 13, 2027 | @ #5 Kansas Jayhawks Legends Classic | L 52-74 | 0-1 | J. Kendrick 11 | J. Kendrick 2 | D. Hatcher 10 |
| November 22, 2027 | @ Rice Owls | W 77-68 | 1-1 | D. Hatcher 25 | J. Kendrick 7 | D. Pack 8 |
| November 24, 2027 | @ Mass.-Lowell River Hawks | L 54-67 | 1-2 | M. Andrews 9 | J. Kendrick 5 | D. Day 9 |
| November 27, 2027 | AUSTIN PEAY GOVERNORS | W 71-57 | 2-2 | A. Braddick 17 | J. Kendrick 5 | D. Hatcher 10 |
| November 29, 2027 | @ #25 Notre Dame Fighting Irish | W 84-81 OT | 3-2 | J. Kendrick 21 | J. Kendrick 4 | D. Hatcher 9 |
| December 3, 2027 | @ #2 Kansas Jayhawks | L 72-80 | 3-3 | D. Pack 15 | J. Kendrick 8 | D. Hatcher 9 |
| December 5, 2027 | @ George Mason Patriots | L 65-86 | 3-4 | D. Hatcher 22 | J. Kendrick 4 | D. Hatcher 10 |
| December 13, 2027 | @ Coastal Carolina Chanticleers | L 72-79 | 3-5 | J. Kendrick 19 | D. Pack 3 | D. Hatcher 10 |
| December 21, 2027 | EASTERN WASHINGTON EAGLES (3-6, 1-6 Away) | - | | | | |
| December 26, 2027 | HOUSTON CHRISTIAN HUSKIES (4-3, 0-0, 0-3 Away)* | - | | | | |
| December 29, 2027 | LAMAR CARDINALS (3-5, 0-0, 3-4 Away)* | - | | | | |
| January 2, 2028 | @ Stephen F. Austin Lumberjacks (3-5, 0-0, 3-2 Home)* | - | | | | |
| January 5, 2028 | @ Texas-Rio Grande Vaqueros (3-5, 0-0, 3-1 Home)* | - | | | | |
| January 9, 2028 | @ Northwestern State Demons (3-5, 0-0, 1-1 Home)* | - | | | | |
| January 12, 2028 | NEW ORLEANS PRIVATEERS (6-2, 0-0, 3-1 Away)* | - | | | | |
| January 16, 2028 | SE LOUISIANA LIONS (2-5, 0-0, 0-2 Away)* | - | | | | |
| January 19, 2028 | @ McNeese State Cowboys (4-3, 0-0, 2-0 Home)* | - | | | | |
| January 23, 2028 | @ Texas A&M-Comm. Lions (1-6, 0-0, 1-2 Home)* | - | | | | |
| January 26, 2028 | @ Nicholls State Colonels (1-7, 0-0, 1-2 Home)* | - | | | | |
| January 30, 2028 | MCNEESE STATE COWBOYS (4-3, 0-0, 2-3 Away)* | - | | | | |
| February 2, 2028 | TEXAS A&M-COMM. LIONS (1-6, 0-0, 0-4 Away)* | - | | | | |
| February 6, 2028 | @ New Orleans Privateers (6-2, 0-0, 3-1 Home)* | - | | | | |
| February 9, 2028 | @ SE Louisiana Lions (2-5, 0-0, 2-3 Home)* | - | | | | |
| February 13, 2028 | STEPHEN F. AUSTIN LUMBERJACKS (3-5, 0-0, 0-2 Away)* | - | | | | |
| February 16, 2028 | TEXAS-RIO GRANDE VAQUEROS (3-5, 0-0, 0-4 Away)* | - | | | | |
| February 20, 2028 | @ Houston Christian Huskies (4-3, 0-0, 4-0 Home)* | - | | | | |
| February 23, 2028 | @ Lamar Cardinals (3-5, 0-0, 0-1 Home)* | - | | | | |
| February 27, 2028 | NICHOLLS STATE COLONELS (1-7, 0-0, 0-5 Away)* | - | | | | |
| March 2, 2028 | INCARNATE WORD CARDINALS (3-5, 0-0, 1-3 Away)* | - | | | | |
