| November 13, 2027 | @ #5 Kansas Jayhawks Legends Classic | L 52-74 | 0-1 | J. Kendrick 11 | J. Kendrick 2 | D. Hatcher 10 |
| November 22, 2027 | @ Rice Owls | W 77-68 | 1-1 | D. Hatcher 25 | J. Kendrick 7 | D. Pack 8 |
| November 24, 2027 | @ Mass.-Lowell River Hawks | L 54-67 | 1-2 | M. Andrews 9 | J. Kendrick 5 | D. Day 9 |
| November 27, 2027 | AUSTIN PEAY GOVERNORS | W 71-57 | 2-2 | A. Braddick 17 | J. Kendrick 5 | D. Hatcher 10 |
| November 29, 2027 | @ #25 Notre Dame Fighting Irish | W 84-81 OT | 3-2 | J. Kendrick 21 | J. Kendrick 4 | D. Hatcher 9 |
| December 3, 2027 | @ #2 Kansas Jayhawks | L 72-80 | 3-3 | D. Pack 15 | J. Kendrick 8 | D. Hatcher 9 |
| December 5, 2027 | @ George Mason Patriots | L 65-86 | 3-4 | D. Hatcher 22 | J. Kendrick 4 | D. Hatcher 10 |
| December 13, 2027 | @ Coastal Carolina Chanticleers | L 72-79 | 3-5 | J. Kendrick 19 | D. Pack 3 | D. Hatcher 10 |
| December 21, 2027 | EASTERN WASHINGTON EAGLES | W 90-72 | 4-5 | D. Day 17 | J. Kendrick 5 | D. Hatcher 8 |
| December 26, 2027 | HOUSTON CHRISTIAN HUSKIES* | W 73-58 | 5-5 | D. Hatcher 28 | D. Pack 4 | D. Hatcher 11 |
| December 29, 2027 | LAMAR CARDINALS* | L 67-81 | 5-6 | D. Day 16 | D. Hatcher 3 | D. Hatcher 8 |
| January 2, 2028 | @ Stephen F. Austin Lumberjacks* | W 81-71 | 6-6 | D. Hatcher 18 | J. Kendrick 8 | D. Hatcher 10 |
| January 5, 2028 | @ Texas-Rio Grande Vaqueros* | L 63-75 | 6-7 | M. Andrews 16 | J. Kendrick 6 | D. Hatcher 11 |
| January 9, 2028 | @ Northwestern State Demons* | L 91-98 | 6-8 | D. Hatcher 16 | J. Kendrick 7 | D. Day 7 |
| January 12, 2028 | NEW ORLEANS PRIVATEERS* | W 85-75 | 7-8 | D. Hatcher 23 | M. Andrews 5 | D. Hatcher 8 |
| January 16, 2028 | SE LOUISIANA LIONS* | L 76-89 | 7-9 | D. Day 21 | J. Kendrick 5 | D. Hatcher 10 |
| January 19, 2028 | @ McNeese State Cowboys* | W 89-68 | 8-9 | J. Kendrick 32 | J. Kendrick 7 | M. Andrews 8 |
| January 23, 2028 | @ Texas A&M-Comm. Lions* | W 82-64 | 9-9 | J. Kendrick 18 | M. Andrews 4 | D. Hatcher 13 |
| January 26, 2028 | @ Nicholls State Colonels* | L 78-86 | 9-10 | M. Andrews 27 | D. Day 5 | M. Andrews 7 |
| January 30, 2028 | MCNEESE STATE COWBOYS* | W 82-70 | 10-10 | D. Hatcher 24 | D. Hatcher 4 | D. Day 7 |
| February 2, 2028 | TEXAS A&M-COMM. LIONS* | W 76-57 | 11-10 | D. Hatcher 19 | D. Day 5 | D. Hatcher 11 |
| February 6, 2028 | @ New Orleans Privateers* | L 75-82 | 11-11 | M. Andrews 21 | J. Kendrick 6 | D. Hatcher 6 |
| February 9, 2028 | @ SE Louisiana Lions* | W 92-90 | 12-11 | D. Hatcher 29 | R. Paige 4 | D. Hatcher 9 |
| February 13, 2028 | STEPHEN F. AUSTIN LUMBERJACKS* | W 83-62 | 13-11 | D. Hatcher 19 | J. Kendrick 5 | M. Andrews 13 |
| February 16, 2028 | TEXAS-RIO GRANDE VAQUEROS* | W 88-71 | 14-11 | J. Kendrick 17 | J. Kendrick 9 | D. Hatcher 13 |
| February 20, 2028 | @ Houston Christian Huskies* | L 74-93 | 14-12 | D. Hatcher 14 | R. Paige 4 | D. Hatcher 7 |
| February 23, 2028 | @ Lamar Cardinals* | L 71-73 | 14-13 | D. Day 20 | J. Kendrick 5 | M. Andrews 9 |
| February 27, 2028 | NICHOLLS STATE COLONELS* | W 81-66 | 15-13 | D. Day 20 | J. Kendrick 4 | D. Hatcher 12 |
| March 2, 2028 | INCARNATE WORD CARDINALS* | W 74-63 | 16-13 | J. Kendrick 16 | D. Day 5 | D. Hatcher 10 |
| March 5, 2028 | LAMAR CARDINALS Southland Tournament | W 94-63 | 17-13 | D. Hatcher 22 | J. Kendrick 9 | M. Andrews 11 |
| March 6, 2028 | @ SE Louisiana Lions Southland Tournament | W 76-59 | 18-13 | D. Hatcher 20 | J. Kendrick 8 | D. Hatcher 12 |
| March 7, 2028 | @ Houston Christian Huskies Southland Tournament | L 78-83 | 18-14 | M. Andrews 26 | J. Kendrick 5 | D. Hatcher 9 |
