| November 15, 2027 | @ Notre Dame Fighting Irish | L 47-75 | 0-1 | T. Holmes 10 | A. Weisse 4 | H. Prescott 7 |
| November 18, 2027 | UTAH VALLEY WOLVERINES | W 73-59 | 1-1 | T. Holmes 16 | A. Weisse 4 | T. Holmes 6 |
| November 22, 2027 | @ Colorado State Rams | L 74-89 | 1-2 | A. McPherson 15 | A. Weisse 9 | T. Holmes 7 |
| November 24, 2027 | @ Oklahoma Sooners | L 57-72 | 1-3 | T. Holmes 16 | A. Weisse 4 | J. Allison 7 |
| November 29, 2027 | NORTH DAKOTA ST. BISON | W 72-58 | 2-3 | A. Weisse 14 | P. Ransom 4 | R. Baxter 8 |
| December 1, 2027 | DUQUESNE DUKES | W 79-70 | 3-3 | A. McPherson 15 | A. Weisse 10 | T. Holmes 4 |
| December 6, 2027 | HOUSTON CHRISTIAN HUSKIES | W 93-74 | 4-3 | A. McPherson 25 | A. Weisse 6 | R. Baxter 8 |
| December 9, 2027 | @ Central Florida Knights | L 72-73 | 4-4 | P. Linney 17 | A. Weisse 6 | T. Holmes 8 |
| December 13, 2027 | @ Kansas City Kangaroos | W 88-69 | 5-4 | T. Holmes 24 | A. Weisse 7 | T. Holmes 9 |
| December 20, 2027 | @ Bucknell Bison (2-5, 1-0 Home) | - | | | | |
| December 23, 2027 | TEXAS A&M-COMM. LIONS (1-6, 0-4 Away) | - | | | | |
| January 2, 2028 | MEMPHIS TIGERS (6-2, 0-0, 0-2 Away)* | - | | | | |
| January 5, 2028 | ALABAMA-BIRMINGHAM BLAZERS (4-5, 0-0, 2-2 Away)* | - | | | | |
| January 9, 2028 | @ South Florida Bulls (3-5, 0-0, 3-1 Home)* | - | | | | |
| January 12, 2028 | @ Charlotte 49ers (5-4, 0-0, 4-1 Home)* | - | | | | |
| January 14, 2028 | @ East Carolina Pirates (2-7, 0-0, 2-2 Home)* | - | | | | |
| January 16, 2028 | TULSA GOLDEN HURRICANES (4-5, 0-0, 1-4 Away)* | - | | | | |
| January 19, 2028 | @ Tulane Green Wave (6-3, 0-0, 6-0 Home)* | - | | | | |
| January 23, 2028 | EAST CAROLINA PIRATES (2-7, 0-0, 0-5 Away)* | - | | | | |
| January 26, 2028 | @ Memphis Tigers (6-2, 0-0, 6-0 Home)* | - | | | | |
| January 30, 2028 | @ Florida Atlantic Owls (5-4, 0-0, 3-1 Home)* | - | | | | |
| February 6, 2028 | WICHITA STATE SHOCKERS (9-0, 0-0, 2-0 Away)* | - | | | | |
| February 9, 2028 | @ Temple Owls (5-5, 0-0, 3-2 Home)* | - | | | | |
| February 13, 2028 | @ Rice Owls (2-6, 0-0, 2-3 Home)* | - | | | | |
| February 16, 2028 | NORTH TEXAS MEAN GREEN (3-6, 0-0, 0-2 Away)* | - | | | | |
| February 20, 2028 | CHARLOTTE 49ERS (5-4, 0-0, 1-2 Away)* | - | | | | |
| February 23, 2028 | TULANE GREEN WAVE (6-3, 0-0, 0-3 Away)* | - | | | | |
| February 27, 2028 | SOUTH FLORIDA BULLS (3-5, 0-0, 0-4 Away)* | - | | | | |
| March 2, 2028 | @ Tulsa Golden Hurricanes (4-5, 0-0, 2-0 Home)* | - | | | | |
