| November 15, 2027 | @ Notre Dame Fighting Irish | L 47-75 | 0-1 | T. Holmes 10 | A. Weisse 4 | H. Prescott 7 |
| November 18, 2027 | UTAH VALLEY WOLVERINES | W 73-59 | 1-1 | T. Holmes 16 | A. Weisse 4 | T. Holmes 6 |
| November 22, 2027 | @ Colorado State Rams | L 74-89 | 1-2 | A. McPherson 15 | A. Weisse 9 | T. Holmes 7 |
| November 24, 2027 | @ Oklahoma Sooners | L 57-72 | 1-3 | T. Holmes 16 | A. Weisse 4 | J. Allison 7 |
| November 29, 2027 | NORTH DAKOTA ST. BISON | W 72-58 | 2-3 | A. Weisse 14 | P. Ransom 4 | R. Baxter 8 |
| December 1, 2027 | DUQUESNE DUKES | W 79-70 | 3-3 | A. McPherson 15 | A. Weisse 10 | T. Holmes 4 |
| December 6, 2027 | HOUSTON CHRISTIAN HUSKIES | W 93-74 | 4-3 | A. McPherson 25 | A. Weisse 6 | R. Baxter 8 |
| December 9, 2027 | @ Central Florida Knights | L 72-73 | 4-4 | P. Linney 17 | A. Weisse 6 | T. Holmes 8 |
| December 13, 2027 | @ Kansas City Kangaroos | W 88-69 | 5-4 | T. Holmes 24 | A. Weisse 7 | T. Holmes 9 |
| December 20, 2027 | @ Bucknell Bison | W 79-59 | 6-4 | J. Allison 19 | A. Weisse 6 | T. Holmes 8 |
| December 23, 2027 | TEXAS A&M-COMM. LIONS | W 78-71 | 7-4 | A. Weisse 21 | A. Weisse 6 | J. Allison 10 |
| January 2, 2028 | MEMPHIS TIGERS* | W 80-73 | 8-4 | T. Holmes 19 | A. Weisse 7 | J. Allison 11 |
| January 5, 2028 | ALABAMA-BIRMINGHAM BLAZERS* | L 62-93 | 8-5 | A. Weisse 21 | A. McPherson 4 | H. Prescott 6 |
| January 9, 2028 | @ South Florida Bulls* | L 73-76 | 8-6 | A. Weisse 19 | A. Weisse 7 | J. Allison 12 |
| January 12, 2028 | @ Charlotte 49ers* | L 65-82 | 8-7 | J. Allison 17 | A. Weisse 4 | J. Allison 7 |
| January 14, 2028 | @ East Carolina Pirates* | L 76-101 | 8-8 | J. Allison 14 | A. Weisse 8 | H. Prescott 6 |
| January 16, 2028 | TULSA GOLDEN HURRICANES* | W 95-73 | 9-8 | T. Holmes 22 | A. Weisse 11 | J. Allison 8 |
| January 19, 2028 | @ Tulane Green Wave* | L 65-82 | 9-9 | T. Holmes 12 | A. Weisse 6 | J. Allison 9 |
| January 23, 2028 | EAST CAROLINA PIRATES* | W 81-70 | 10-9 | A. Weisse 23 | A. Weisse 4 | H. Prescott 9 |
| January 26, 2028 | @ Memphis Tigers* | L 75-91 | 10-10 | T. Holmes 20 | A. Weisse 4 | H. Prescott 13 |
| January 30, 2028 | @ Florida Atlantic Owls* | L 73-83 | 10-11 | A. Weisse 20 | A. Weisse 4 | J. Allison 7 |
| February 6, 2028 | #15 WICHITA STATE SHOCKERS* | W 79-72 | 11-11 | T. Holmes 20 | J. Allison 4 | H. Prescott 8 |
| February 9, 2028 | @ Temple Owls* | L 69-86 | 11-12 | T. Holmes 18 | A. Weisse 8 | H. Prescott 7 |
| February 13, 2028 | @ Rice Owls* | L 64-79 | 11-13 | H. Prescott 13 | A. Weisse 7 | H. Prescott 9 |
| February 16, 2028 | NORTH TEXAS MEAN GREEN* | W 73-71 | 12-13 | T. Holmes 25 | P. Linney 6 | T. Holmes 14 |
| February 20, 2028 | CHARLOTTE 49ERS* | W 77-61 | 13-13 | J. Moore 17 | A. Weisse 8 | J. Allison 7 |
| February 23, 2028 | TULANE GREEN WAVE* | W 79-71 | 14-13 | J. Allison 13 | A. Weisse 6 | H. Prescott 11 |
| February 27, 2028 | SOUTH FLORIDA BULLS* | W 77-74 | 15-13 | T. Holmes 16 | A. Weisse 9 | R. Baxter 8 |
| March 2, 2028 | @ Tulsa Golden Hurricanes* | L 72-85 | 15-14 | J. Moore 15 | A. Weisse 9 | H. Prescott 9 |
| March 7, 2028 | @ North Texas Mean Green AAC Tournament | L 76-83 | 15-15 | A. McPherson 19 | P. Linney 4 | T. Holmes 8 |
