| November 15, 2027 | @ Clemson Tigers | W 96-90 OT | 1-0 | D. Hamilton 27 | T. Hobbs 8 | D. Hamilton 8 |
| November 19, 2027 | @ Portland State Vikings | W 91-79 | 2-0 | D. Hamilton 31 | T. Neterville 9 | K. Martinez 7 |
| November 22, 2027 | @ DePaul Blue Demons | L 60-78 | 2-1 | D. Hamilton 14 | T. Neterville 4 | B. Smith 8 |
| November 25, 2027 | @ Louisiana State Fighting Tigers ESPN Events Invitational | W 80-60 | 3-1 | B. Smith 20 | T. Neterville 8 | B. Smith 9 |
| November 26, 2027 | @ #19 Creighton Blue Jays ESPN Events Invitational | L 74-78 | 3-2 | T. Neterville 19 | L. Williams 4 | K. Martinez 8 |
| November 30, 2027 | @ Oklahoma State Cowboys | L 61-78 | 3-3 | M. Lewis 11 | T. Hobbs 4 | B. Smith 7 |
| December 6, 2027 | @ North Dakota Fighting Hawks | W 79-65 | 4-3 | T. Neterville 17 | T. Neterville 3 | B. Smith 8 |
| December 9, 2027 | COLUMBIA LIONS | W 90-77 | 5-3 | B. Smith 19 | D. Hamilton 4 | B. Smith 6 |
| December 14, 2027 | @ Montana State Bobcats | L 74-87 | 5-4 | T. Neterville 17 | T. Neterville 7 | K. Martinez 5 |
| December 20, 2027 | @ Wisconsin Badgers (6-2, 3-1 Home) | - | | | | |
| December 26, 2027 | @ Eastern Michigan Eagles (5-3, 0-0, 3-0 Home)* | - | | | | |
| December 29, 2027 | @ Northern Illinois Huskies (5-2, 0-0, 3-0 Home)* | - | | | | |
| January 2, 2028 | BUFFALO BULLS (1-7, 0-0, 1-5 Away)* | - | | | | |
| January 5, 2028 | CENTRAL MICHIGAN CHIPPEWAS (4-4, 0-0, 2-4 Away)* | - | | | | |
| January 9, 2028 | AKRON ZIPS (5-2, 0-0, 0-1 Away)* | - | | | | |
| January 12, 2028 | @ Miami (OH) RedHawks (4-4, 0-0, 2-0 Home)* | - | | | | |
| January 16, 2028 | BOWLING GREEN STATE FALCONS (4-4, 0-0, 1-4 Away)* | - | | | | |
| January 19, 2028 | @ Ohio Bobcats (4-4, 0-0, 2-0 Home)* | - | | | | |
| January 23, 2028 | @ Ball State Cardinals (2-5, 0-0, 1-1 Home)* | - | | | | |
| January 26, 2028 | @ Bowling Green State Falcons (4-4, 0-0, 3-0 Home)* | - | | | | |
| January 30, 2028 | OHIO BOBCATS (4-4, 0-0, 2-3 Away)* | - | | | | |
| February 2, 2028 | BALL STATE CARDINALS (2-5, 0-0, 1-4 Away)* | - | | | | |
| February 6, 2028 | MIAMI (OH) REDHAWKS (4-4, 0-0, 2-4 Away)* | - | | | | |
| February 9, 2028 | @ Kent State Golden Flashes (6-3, 0-0, 5-0 Home)* | - | | | | |
| February 13, 2028 | @ Buffalo Bulls (1-7, 0-0, 0-1 Home)* | - | | | | |
| February 16, 2028 | @ Central Michigan Chippewas (4-4, 0-0, 2-0 Home)* | - | | | | |
| February 20, 2028 | EASTERN MICHIGAN EAGLES (5-3, 0-0, 2-3 Away)* | - | | | | |
| February 23, 2028 | NORTHERN ILLINOIS HUSKIES (5-2, 0-0, 2-2 Away)* | - | | | | |
| February 27, 2028 | KENT STATE GOLDEN FLASHES (6-3, 0-0, 0-2 Away)* | - | | | | |
| March 2, 2028 | @ Western Michigan Broncos (2-6, 0-0, 2-0 Home)* | - | | | | |
