| November 13, 2027 | HOWARD BISON | L 57-81 | 0-1 | K. Stokes 13 | K. Stokes 8 | K. Adams 9 |
| November 15, 2027 | CAL ST. NORTHRIDGE MATADORS | L 90-92 | 0-2 | T. Phillips 28 | K. Stokes 5 | J. Phillips 16 |
| November 17, 2027 | NC-CENTRAL EAGLES | W 87-73 | 1-2 | T. Phillips 24 | K. Stokes 8 | J. Dondon 11 |
| November 25, 2027 | SOUTH CAROLINA GAMECOCKS Paradise Jam | L 73-88 | 1-3 | T. Phillips 24 | K. Stokes 6 | T. Phillips 6 |
| November 28, 2027 | FLORIDA INTERNATIONAL PANTHERS | W 89-75 | 2-3 | K. Stokes 23 | K. Stokes 7 | J. Dondon 11 |
| December 2, 2027 | WESTERN MICHIGAN BRONCOS | W 82-77 | 3-3 | J. Phillips 16 | K. Stokes 4 | J. Dondon 11 |
| December 6, 2027 | @ Saint Josephs Hawks | W 88-81 | 4-3 | T. Phillips 24 | T. Phillips 5 | J. Dondon 8 |
| December 12, 2027 | SIENA SAINTS | W 101-88 | 5-3 | T. Phillips 22 | K. Stokes 7 | J. Phillips 11 |
| December 20, 2027 | CAL ST. FULLERTON TITANS | L 85-88 | 5-4 | T. Phillips 19 | K. Stokes 5 | T. Phillips 9 |
| December 26, 2027 | @ Florida State Seminoles* | W 79-76 | 6-4 | K. Stokes 15 | K. Stokes 4 | T. Phillips 9 |
| December 28, 2027 | @ Wake Forest Demon Deacons* | L 74-93 | 6-5 | K. Stokes 17 | K. Stokes 4 | A. Wright 6 |
| January 2, 2028 | SYRACUSE ORANGE* | L 85-95 | 6-6 | K. Stokes 20 | T. Phillips 5 | J. Dondon 6 |
| January 4, 2028 | @ Boston College Eagles* | L 90-105 | 6-7 | T. Phillips 32 | K. Stokes 7 | J. Phillips 8 |
| January 9, 2028 | CALIFORNIA GOLDEN BEARS* | L 84-90 OT | 6-8 | T. Phillips 28 | K. Stokes 7 | T. Phillips 8 |
| January 11, 2028 | @ Miami (FL) Hurricanes* | W 87-75 | 7-8 | T. Phillips 29 | K. Stokes 4 | J. Dondon 10 |
| January 16, 2028 | #6 LOUISVILLE CARDINALS* | W 84-77 | 8-8 | K. Stokes 17 | K. Stokes 4 | K. Adams 7 |
| January 18, 2028 | @ Stanford Cardinal* | L 76-100 | 8-9 | K. Stokes 34 | B. Leith 4 | J. Dondon 9 |
| January 23, 2028 | CLEMSON TIGERS* | W 92-82 | 9-9 | K. Stokes 28 | T. Martinez 5 | J. Dondon 14 |
| January 25, 2028 | #25 NORTH CAROLINA TAR HEELS* | W 84-79 | 10-9 | K. Stokes 27 | K. Stokes 6 | J. Dondon 6 |
| January 30, 2028 | @ Notre Dame Fighting Irish* | L 78-95 | 10-10 | T. Phillips 26 | K. Stokes 5 | J. Dondon 8 |
| February 1, 2028 | GEORGIA TECH YELLOW JACKETS* | W 81-66 | 11-10 | T. Phillips 19 | K. Stokes 6 | J. Dondon 9 |
| February 6, 2028 | VIRGINIA TECH HOKIES* | L 73-92 | 11-11 | K. Stokes 12 | K. Stokes 5 | J. Dondon 6 |
| February 8, 2028 | @ Pittsburgh Panthers* | L 64-90 | 11-12 | J. Phillips 19 | K. Stokes 4 | J. Dondon 8 |
| February 13, 2028 | NC-STATE WOLFPACK* | W 73-61 | 12-12 | J. Dondon 17 | K. Adams 5 | T. Phillips 6 |
| February 15, 2028 | @ #12 Virginia Cavaliers* | L 86-101 | 12-13 | T. Phillips 24 | K. Stokes 7 | J. Dondon 7 |
| February 20, 2028 | #1 DUKE BLUE DEVILS* | L 71-78 | 12-14 | K. Stokes 22 | K. Stokes 7 | J. Phillips 11 |
| February 22, 2028 | PITTSBURGH PANTHERS* | W 75-68 | 13-14 | T. Phillips 16 | K. Stokes 6 | J. Dondon 10 |
| February 27, 2028 | @ NC-State Wolfpack* | L 71-79 | 13-15 | K. Stokes 12 | K. Stokes 7 | J. Dondon 8 |
| March 1, 2028 | @ #19 Syracuse Orange* | L 65-91 | 13-16 | K. Stokes 26 | K. Stokes 3 | K. Stokes 4 |
| March 8, 2028 | PITTSBURGH PANTHERS (14-16, 2-8 Away) ACC Tournament | - | | | | |
