| November 15, 2027 | WILLIAM & MARY TRIBE | L 57-66 | 0-1 | J. Brittian 15 | J. Wilkerson 5 | J. Brittian 7 |
| November 21, 2027 | @ Arizona State Sun Devils Hall of Fame Classic | W 71-52 | 1-1 | T. Wise 19 | J. Wilkerson 6 | J. Brittian 9 |
| November 22, 2027 | DUQUESNE DUKES Hall of Fame Classic | L 63-94 | 1-2 | T. Wise 16 | J. Wilkerson 4 | J. Wilkerson 6 |
| November 26, 2027 | @ Oklahoma State Cowboys | L 76-95 | 1-3 | T. Wise 30 | J. Wilkerson 7 | A. Giles 8 |
| November 28, 2027 | @ MD-Baltimore County Retrievers | L 73-91 | 1-4 | T. Wise 16 | J. Wilkerson 4 | A. Giles 13 |
| December 1, 2027 | RICHMOND SPIDERS | L 83-91 | 1-5 | T. Wise 20 | J. Wilkerson 5 | A. Giles 8 |
| December 6, 2027 | @ #11 Creighton Blue Jays | L 52-80 | 1-6 | T. Wise 14 | T. Wise 4 | A. Giles 10 |
| December 8, 2027 | @ Akron Zips | L 66-83 | 1-7 | T. Wise 16 | A. Giles 3 | J. Brittian 11 |
| December 12, 2027 | HIGH POINT PANTHERS | L 73-83 | 1-8 | T. Wise 20 | T. Wise 6 | J. Wilkerson 6 |
| December 15, 2027 | @ Oakland Golden Grizzlies | L 64-80 | 1-9 | J. Wilkerson 15 | T. Wise 3 | A. Giles 10 |
| December 20, 2027 | @ Xavier Musketeers | W 67-65 | 2-9 | D. McInnis 14 | J. Wilkerson 5 | A. Giles 6 |
| December 26, 2027 | @ St. Bonaventure Bonnies | L 69-82 | 2-10 | J. Brittian 21 | A. Giles 3 | J. Wilkerson 8 |
| January 4, 2028 | NEVADA WOLFPACK* | W 78-60 | 3-10 | D. Houston 14 | T. Wise 4 | A. Giles 9 |
| January 6, 2028 | FRESNO STATE BULLDOGS* | L 65-74 | 3-11 | J. Brittian 15 | D. Houston 5 | A. Giles 8 |
| January 9, 2028 | NEVADA-LAS VEGAS RUNNIN' REBELS* | L 55-71 | 3-12 | J. Wilkerson 14 | D. Houston 4 | S. Kidd 8 |
| January 11, 2028 | @ San Diego State Aztecs* | L 61-82 | 3-13 | J. Brittian 13 | J. Wilkerson 5 | A. Giles 10 |
| January 13, 2028 | NEW MEXICO LOBOS* | L 70-75 | 3-14 | J. Brittian 19 | J. Wilkerson 5 | A. Giles 8 |
| January 16, 2028 | @ Nevada Wolfpack* | L 78-81 | 3-15 | T. Wise 20 | J. Wilkerson 8 | J. Brittian 10 |
| January 18, 2028 | @ Fresno State Bulldogs* | L 77-90 | 3-16 | D. Houston 20 | J. Wilkerson 8 | J. Wilkerson 6 |
| January 23, 2028 | @ Boise State Broncos* | L 69-78 | 3-17 | D. Houston 15 | J. Wilkerson 6 | A. Giles 8 |
| January 25, 2028 | @ Colorado State Rams* | L 65-83 | 3-18 | J. Brittian 24 | J. Wilkerson 7 | D. Houston 6 |
| January 30, 2028 | WYOMING COWBOYS* | W 92-74 | 4-18 | T. Wise 18 | J. Wilkerson 9 | J. Wilkerson 8 |
| February 1, 2028 | @ Air Force Falcons* | L 76-83 | 4-19 | T. Wise 19 | D. Houston 4 | A. Giles 8 |
| February 8, 2028 | BOISE STATE BRONCOS* | L 68-78 | 4-20 | T. Wise 17 | J. Wilkerson 5 | J. Wilkerson 5 |
| February 10, 2028 | @ Utah State Aggies* | L 62-77 | 4-21 | T. Patton 14 | J. Wilkerson 4 | S. Kidd 9 |
| February 13, 2028 | SAN DIEGO STATE AZTECS* | L 59-84 | 4-22 | D. McInnis 13 | J. Wilkerson 3 | J. Wilkerson 9 |
| February 20, 2028 | COLORADO STATE RAMS* | W 82-71 | 5-22 | J. Wilkerson 22 | J. Wilkerson 4 | S. Kidd 7 |
| February 22, 2028 | @ Wyoming Cowboys* | W 70-52 | 6-22 | D. McInnis 16 | J. Wilkerson 8 | S. Kidd 11 |
| February 27, 2028 | AIR FORCE FALCONS* | W 69-55 | 7-22 | J. Wilkerson 14 | J. Wilkerson 3 | J. Wilkerson 5 |
| March 1, 2028 | @ Nevada-Las Vegas Runnin' Rebels* | W 83-81 | 8-22 | J. Wilkerson 18 | J. Wilkerson 8 | J. Brittian 8 |
| March 7, 2028 | @ Wyoming Cowboys MWC Tournament | L 75-84 | 8-23 | T. Wise 19 | J. Brittian 5 | A. Giles 10 |
