| November 15, 2027 | TOWSON TIGERS | L 71-81 | 0-1 | D. Strohm 16 | W. Tann 7 | D. Townes 11 |
| November 18, 2027 | SAINT FRANCIS (PA) RED FLASH | W 84-64 | 1-1 | E. Wilcox 19 | W. Tann 5 | D. Strohm 10 |
| November 21, 2027 | DUQUESNE DUKES Hall of Fame Classic | L 85-90 OT | 1-2 | E. Wilcox 21 | W. Tann 7 | E. Wilcox 9 |
| November 25, 2027 | @ San Diego Toreros | L 82-92 | 1-3 | D. Townes 18 | W. Tann 4 | R. Chenowith 6 |
| November 29, 2027 | MONTANA STATE BOBCATS | W 77-52 | 2-3 | E. Wilcox 18 | W. Tann 6 | E. Wilcox 11 |
| December 2, 2027 | HOFSTRA PRIDE | L 68-75 | 2-4 | E. Wilcox 23 | W. Tann 4 | E. Wilcox 11 |
| December 6, 2027 | MEMPHIS TIGERS | W 82-72 | 3-4 | D. Townes 18 | D. Strohm 5 | D. Townes 8 |
| December 13, 2027 | @ Oregon State Beavers | W 78-60 | 4-4 | D. Townes 21 | W. Tann 9 | E. Wilcox 11 |
| December 20, 2027 | NORTHWESTERN WILDCATS | W 79-76 OT | 5-4 | E. Wilcox 22 | W. Tann 8 | D. Townes 8 |
| December 26, 2027 | DEPAUL BLUE DEMONS* | W 96-84 | 6-4 | R. Chenowith 27 | D. Strohm 4 | R. Chenowith 5 |
| December 28, 2027 | @ Connecticut Huskies* | W 71-56 | 7-4 | W. Tann 19 | G. Romano 4 | R. Chenowith 8 |
| December 30, 2027 | @ Xavier Musketeers* | L 57-76 | 7-5 | D. Townes 15 | W. Tann 4 | D. Strohm 6 |
| January 2, 2028 | GEORGETOWN HOYAS* | L 67-70 | 7-6 | E. Wilcox 17 | W. Tann 5 | E. Wilcox 12 |
| January 4, 2028 | @ Providence Friars* | L 74-75 | 7-7 | D. Strohm 15 | D. Strohm 4 | R. Chenowith 7 |
| January 6, 2028 | #17 CREIGHTON BLUE JAYS* | W 59-56 | 8-7 | D. Strohm 10 | K. Mickeal 3 | R. Chenowith 7 |
| January 13, 2028 | SETON HALL PIRATES* | W 76-56 | 9-7 | R. Chenowith 20 | W. Tann 5 | E. Wilcox 12 |
| January 18, 2028 | @ #24 Butler Bulldogs* | L 54-73 | 9-8 | R. Chenowith 18 | K. Mickeal 4 | R. Chenowith 10 |
| January 20, 2028 | @ #1 Marquette Golden Eagles* | L 61-91 | 9-9 | D. Townes 19 | W. Tann 4 | R. Chenowith 7 |
| January 27, 2028 | #19 VILLANOVA WILDCATS* | W 81-79 | 10-9 | R. Chenowith 15 | K. Mickeal 5 | W. Tann 5 |
| February 1, 2028 | PROVIDENCE FRIARS* | W 75-73 OT | 11-9 | E. Wilcox 25 | W. Tann 5 | E. Wilcox 12 |
| February 3, 2028 | @ Seton Hall Pirates* | L 73-83 | 11-10 | D. Townes 19 | D. Strohm 6 | E. Wilcox 8 |
| February 8, 2028 | #1 MARQUETTE GOLDEN EAGLES* | L 86-95 | 11-11 | E. Wilcox 21 | W. Tann 4 | R. Chenowith 6 |
| February 10, 2028 | #25 BUTLER BULLDOGS* | W 78-72 | 12-11 | E. Wilcox 22 | D. Strohm 6 | D. Strohm 6 |
| February 15, 2028 | @ Creighton Blue Jays* | W 69-67 | 13-11 | R. Chenowith 11 | W. Tann 3 | D. Townes 6 |
| February 17, 2028 | @ Villanova Wildcats* | L 62-83 | 13-12 | D. Strohm 18 | W. Tann 5 | E. Wilcox 7 |
| February 22, 2028 | @ Georgetown Hoyas* | W 78-73 OT | 14-12 | E. Wilcox 18 | D. Strohm 4 | R. Chenowith 10 |
| February 24, 2028 | @ DePaul Blue Demons* | L 67-83 | 14-13 | D. Townes 17 | W. Tann 6 | R. Chenowith 7 |
| March 1, 2028 | XAVIER MUSKETEERS* | W 72-61 | 15-13 | R. Chenowith 15 | D. Strohm 5 | G. Romano 10 |
| March 3, 2028 | CONNECTICUT HUSKIES* | L 55-60 | 15-14 | K. Mickeal 9 | W. Tann 4 | D. Townes 8 |
| March 10, 2028 | SETON HALL PIRATES Big East Tournament | W 91-76 | 16-14 | D. Strohm 20 | W. Tann 8 | D. Townes 6 |
| March 11, 2028 | @ #1 Marquette Golden Eagles Big East Tournament | L 60-77 | 16-15 | E. Wilcox 13 | D. Townes 3 | D. Townes 6 |
