| November 16, 2024 | NC-STATE WOLFPACK | L 79-84 | 0-1 | R. Burke 24 | C. Carr 4 | J. Lawrence 5 |
| November 19, 2024 | ERIE FREIGHTERS | W 67-51 | 1-1 | A. Majerus 15 | M. Bird 3 | A. Majerus 5 |
| November 23, 2024 | PRESBYTERIAN BLUE HOSE | W 68-56 | 2-1 | R. Burke 24 | C. Carr 8 | R. Burke 10 |
| November 30, 2024 | NORTHWESTERN WILDCATS | L 56-73 | 2-2 | R. Burke 18 | C. Carr 5 | R. Burke 7 |
| December 7, 2024 | HOFSTRA PRIDE | W 72-63 | 3-2 | A. Woodward 22 | R. Burke 5 | J. Lawrence 8 |
| December 14, 2024 | @ #8 Arizona Wildcats | L 55-62 | 3-3 | A. Woodward 28 | C. Carr 4 | J. Lawrence 6 |
| December 16, 2024 | PENN STATE NITTANY LIONS Las Vegas Showdown | L 55-71 | 3-4 | A. Woodward 13 | C. Carr 4 | J. Lawrence 11 |
| December 21, 2024 | WASHINGTON STATE COUGARS | W 71-64 | 4-4 | A. Woodward 15 | A. Majerus 3 | A. Majerus 8 |
| December 23, 2024 | MD-BALTIMORE COUNTY RETRIEVERS | W 84-67 | 5-4 | R. Burke 22 | A. Woodward 5 | R. Burke 9 |
| December 26, 2024 | XAVIER MUSKETEERS* | L 73-78 | 5-5 | A. Woodward 18 | C. Carr 4 | R. Burke 5 |
| December 30, 2024 | @ #9 Providence Friars* | L 47-75 | 5-6 | R. Burke 12 | C. Carr 4 | A. Majerus 9 |
| January 2, 2025 | CREIGHTON BLUE JAYS* | L 67-84 | 5-7 | A. Woodward 16 | A. Woodward 4 | A. Majerus 8 |
| January 4, 2025 | #15 BUTLER BULLDOGS* | W 68-65 | 6-7 | A. Woodward 20 | C. Carr 7 | A. Majerus 10 |
| January 6, 2025 | @ Villanova Wildcats* | L 71-89 | 6-8 | A. Woodward 23 | M. Palmer 4 | J. Lawrence 7 |
| January 11, 2025 | #9 MARQUETTE GOLDEN EAGLES* | L 64-72 | 6-9 | A. Woodward 20 | M. Palmer 6 | J. Lawrence 7 |
| January 13, 2025 | @ Connecticut Huskies* | L 53-69 | 6-10 | A. Woodward 11 | C. Carr 3 | R. Burke 7 |
| January 18, 2025 | DEPAUL BLUE DEMONS (7-9, 1-6, 0-3 Away)* | - | | | | |
| January 20, 2025 | GEORGETOWN HOYAS (13-5, 5-2, 3-3 Away)* | - | | | | |
| January 25, 2025 | @ Seton Hall Pirates (9-7, 1-5, 8-3 Home)* | - | | | | |
| January 27, 2025 | @ Butler Bulldogs (12-4, 4-2, 9-2 Home)* | - | | | | |
| February 1, 2025 | VILLANOVA WILDCATS (9-9, 3-4, 2-4 Away)* | - | | | | |
| February 3, 2025 | PROVIDENCE FRIARS (15-3, 5-2, 4-1 Away)* | - | | | | |
| February 8, 2025 | @ Georgetown Hoyas (13-5, 5-2, 8-1 Home)* | - | | | | |
| February 10, 2025 | @ DePaul Blue Demons (7-9, 1-6, 7-5 Home)* | - | | | | |
| February 17, 2025 | SETON HALL PIRATES (9-7, 1-5, 0-3 Away)* | - | | | | |
| February 22, 2025 | CONNECTICUT HUSKIES (11-6, 3-4, 2-3 Away)* | - | | | | |
| February 27, 2025 | @ Marquette Golden Eagles (14-1, 6-0, 10-0 Home)* | - | | | | |
| March 1, 2025 | @ Xavier Musketeers (9-6, 3-3, 7-2 Home)* | - | | | | |
| March 3, 2025 | @ Creighton Blue Jays (11-4, 4-2, 7-2 Home)* | - | | | | |
