| November 15, 2027 | WAKE FOREST DEMON DEACONS | W 91-75 | 1-0 | J. Emanuel 15 | G. Stanton 6 | R. Heard 12 |
| November 18, 2027 | PRINCETON TIGERS | W 75-71 | 2-0 | M. Morris 16 | G. Stanton 4 | G. Burke 9 |
| November 21, 2027 | HAWAII RAINBOW WARRIORS WSSN Classic | W 77-63 | 3-0 | R. Gandy 16 | G. Stanton 6 | R. Gandy 8 |
| November 22, 2027 | @ Missouri Tigers WSSN Classic | W 68-65 | 4-0 | R. Heard 17 | R. Heard 4 | R. Heard 16 |
| November 23, 2027 | @ George Mason Patriots WSSN Classic | W 78-68 | 5-0 | J. Emanuel 18 | G. Stanton 7 | Q. Acorn 9 |
| November 25, 2027 | LOUISIANA-MONROE WARHAWKS | L 59-64 | 5-1 | G. Stanton 14 | D. Thompson 5 | R. Heard 11 |
| November 29, 2027 | @ #13 Louisville Cardinals | W 94-88 | 6-1 | R. Gandy 18 | D. Thompson 5 | Q. Acorn 7 |
| December 6, 2027 | ILLINOIS-CHICAGO FLAMES | W 79-54 | 7-1 | J. Emanuel 19 | J. Emanuel 8 | R. Heard 10 |
| December 8, 2027 | VERMONT CATAMOUNTS | W 90-74 | 8-1 | G. Stanton 21 | G. Stanton 5 | R. Heard 13 |
| December 13, 2027 | OREGON DUCKS | W 86-67 | 9-1 | G. Stanton 21 | G. Stanton 6 | R. Heard 12 |
| December 20, 2027 | HOLY CROSS CRUSADERS | L 88-92 OT | 9-2 | Q. Acorn 15 | G. Stanton 7 | R. Heard 18 |
| December 26, 2027 | @ #2 Marquette Golden Eagles* | L 77-95 | 9-3 | R. Heard 18 | G. Stanton 5 | R. Heard 11 |
| December 30, 2027 | #16 CREIGHTON BLUE JAYS* | W 84-76 | 10-3 | Q. Acorn 18 | G. Stanton 7 | R. Heard 12 |
| January 2, 2028 | @ #24 Butler Bulldogs* | L 60-75 | 10-4 | R. Heard 12 | G. Stanton 3 | R. Heard 9 |
| January 4, 2028 | #20 VILLANOVA WILDCATS* | L 69-82 | 10-5 | J. Emanuel 18 | G. Stanton 7 | R. Heard 9 |
| January 11, 2028 | @ Providence Friars* | L 64-69 | 10-6 | G. Stanton 16 | G. Stanton 3 | R. Heard 9 |
| January 13, 2028 | @ St. Johns Red Storm* | L 56-76 | 10-7 | G. Stanton 12 | Q. Acorn 4 | R. Heard 13 |
| January 20, 2028 | XAVIER MUSKETEERS* | W 75-64 | 11-7 | R. Heard 12 | G. Stanton 3 | R. Heard 14 |
| January 23, 2028 | CONNECTICUT HUSKIES* | W 63-61 | 12-7 | Q. Acorn 13 | G. Stanton 5 | R. Heard 12 |
| January 27, 2028 | @ Georgetown Hoyas* | W 79-69 | 13-7 | R. Heard 21 | G. Stanton 6 | R. Heard 10 |
| January 30, 2028 | @ DePaul Blue Demons* | L 75-77 | 13-8 | Q. Acorn 14 | G. Stanton 8 | R. Gandy 13 |
| February 1, 2028 | @ #22 Villanova Wildcats* | L 70-98 | 13-9 | R. Gandy 11 | J. Emanuel 5 | R. Heard 8 |
| February 3, 2028 | ST. JOHNS RED STORM* | W 83-73 | 14-9 | R. Gandy 24 | J. Emanuel 7 | R. Heard 10 |
| February 8, 2028 | PROVIDENCE FRIARS* | L 51-65 | 14-10 | R. Rhodes 11 | G. Stanton 5 | R. Heard 11 |
| February 10, 2028 | @ Creighton Blue Jays* | W 81-73 | 15-10 | J. Emanuel 16 | G. Stanton 8 | Q. Acorn 11 |
| February 15, 2028 | GEORGETOWN HOYAS* | W 84-78 | 16-10 | G. Stanton 17 | G. Stanton 5 | Q. Acorn 6 |
| February 17, 2028 | DEPAUL BLUE DEMONS* | W 75-54 | 17-10 | R. Heard 20 | J. Emanuel 4 | R. Heard 9 |
| February 22, 2028 | @ Xavier Musketeers* | W 78-69 | 18-10 | R. Heard 20 | G. Stanton 8 | R. Gandy 8 |
| February 24, 2028 | @ Connecticut Huskies* | L 57-69 | 18-11 | Q. Acorn 19 | G. Stanton 6 | G. Burke 8 |
| March 1, 2028 | #1 MARQUETTE GOLDEN EAGLES* | L 64-86 | 18-12 | R. Heard 24 | G. Stanton 7 | R. Heard 12 |
| March 3, 2028 | #23 BUTLER BULLDOGS* | W 77-64 | 19-12 | R. Gandy 19 | G. Stanton 4 | Q. Acorn 6 |
| March 10, 2028 | @ St. Johns Red Storm Big East Tournament | L 76-91 | 19-13 | R. Gandy 19 | J. Emanuel 6 | R. Heard 9 |
