| November 15, 2027 | ROBERT MORRIS COLONIALS | W 80-74 OT | 1-0 | L. Cassel 19 | M. Hare 5 | L. Cassel 9 |
| November 18, 2027 | @ Kentucky Wildcats | W 92-85 | 2-0 | C. Daniel 15 | M. Hare 9 | L. Cassel 9 |
| November 23, 2027 | MD-EASTERN SHORE HAWKS | W 81-61 | 3-0 | T. Lewis 14 | J. Payne 5 | J. Evans 12 |
| November 25, 2027 | MURRAY STATE RACERS | W 110-96 | 4-0 | L. Cassel 27 | M. Hare 7 | L. Cassel 7 |
| November 29, 2027 | TEMPLE OWLS | W 89-80 | 5-0 | L. Cassel 19 | J. Payne 6 | L. Cassel 6 |
| December 6, 2027 | BELLARMINE KNIGHTS | W 90-66 | 6-0 | L. Cassel 16 | M. Hare 6 | L. Cassel 9 |
| December 9, 2027 | WASHINGTON STATE COUGARS Jimmy V Classic | L 89-97 | 6-1 | C. Daniel 16 | M. Hare 6 | C. Daniel 5 |
| December 13, 2027 | @ Michigan State Spartans | L 76-77 OT | 6-2 | R. King 21 | T. Lewis 3 | L. Cassel 8 |
| December 16, 2027 | @ #8 Arizona Wildcats | L 57-85 | 6-3 | M. Hare 12 | M. Hare 3 | J. Evans 8 |
| December 20, 2027 | ALCORN STATE BRAVES (3-6, 2-4 Away) | - | | | | |
| December 27, 2027 | ARKANSAS-PINE BLUFF GOLDEN LIONS (4-5, 1-2 Away) | - | | | | |
| January 2, 2028 | @ New Mexico Lobos (4-4, 0-0, 2-2 Home)* | - | | | | |
| January 6, 2028 | @ Air Force Falcons (4-4, 0-0, 2-2 Home)* | - | | | | |
| January 9, 2028 | @ Fresno State Bulldogs (8-0, 0-0, 6-0 Home)* | - | | | | |
| January 11, 2028 | SAN JOSE STATE SPARTANS (1-9, 0-0, 0-5 Away)* | - | | | | |
| January 16, 2028 | NEW MEXICO LOBOS (4-4, 0-0, 2-2 Away)* | - | | | | |
| January 20, 2028 | @ Wyoming Cowboys (5-4, 0-0, 4-0 Home)* | - | | | | |
| January 25, 2028 | UTAH STATE AGGIES (4-5, 0-0, 1-4 Away)* | - | | | | |
| January 27, 2028 | NEVADA-LAS VEGAS RUNNIN' REBELS (4-5, 0-0, 1-2 Away)* | - | | | | |
| January 30, 2028 | COLORADO STATE RAMS (2-7, 0-0, 0-6 Away)* | - | | | | |
| February 6, 2028 | BOISE STATE BRONCOS (9-2, 0-0, 2-2 Away)* | - | | | | |
| February 8, 2028 | NEVADA WOLFPACK (1-8, 0-0, 0-3 Away)* | - | | | | |
| February 10, 2028 | @ Nevada-Las Vegas Runnin' Rebels (4-5, 0-0, 3-2 Home)* | - | | | | |
| February 13, 2028 | @ San Jose State Spartans (1-9, 0-0, 0-3 Home)* | - | | | | |
| February 15, 2028 | @ Colorado State Rams (2-7, 0-0, 2-1 Home)* | - | | | | |
| February 17, 2028 | WYOMING COWBOYS (5-4, 0-0, 1-4 Away)* | - | | | | |
| February 22, 2028 | @ Utah State Aggies (4-5, 0-0, 3-0 Home)* | - | | | | |
| February 27, 2028 | FRESNO STATE BULLDOGS (8-0, 0-0, 2-0 Away)* | - | | | | |
| March 1, 2028 | @ Boise State Broncos (9-2, 0-0, 4-0 Home)* | - | | | | |
