| November 18, 2027 | @ Florida State Seminoles | L 81-82 | 0-1 | O. Cotton 18 | C. Wallace 6 | O. Cotton 7 |
| November 22, 2027 | @ Northeastern Huskies | W 89-73 | 1-1 | T. Nelson 15 | C. Wallace 7 | T. Nelson 7 |
| November 25, 2027 | @ Southern Mississippi Golden Eagles | L 59-81 | 1-2 | T. Armstead 13 | J. Tan 3 | O. Cotton 8 |
| November 29, 2027 | @ Virginia Tech Hokies | L 66-77 | 1-3 | M. Greer 19 | C. Wallace 8 | O. Cotton 11 |
| December 3, 2027 | MD-EASTERN SHORE HAWKS | W 100-93 OT | 2-3 | T. Nelson 21 | C. Wallace 5 | O. Cotton 11 |
| December 13, 2027 | @ Rutgers Scarlet Knights | W 89-79 | 3-3 | M. Greer 22 | C. Wallace 5 | O. Cotton 17 |
| December 16, 2027 | @ Baylor Bears Diamond Head Classic | L 73-87 | 3-4 | M. Greer 20 | C. Wallace 4 | M. Greer 11 |
| December 21, 2027 | NIAGARA PURPLE EAGLES | W 80-79 | 4-4 | M. Greer 15 | T. Nelson 7 | O. Cotton 10 |
| December 23, 2027 | @ Columbia Lions | W 88-78 | 5-4 | M. Greer 16 | C. Wallace 5 | D. Ash 7 |
| December 26, 2027 | EVANSVILLE PURPLE ACES* | W 69-62 | 6-4 | O. Cotton 17 | C. Wallace 4 | M. Greer 8 |
| December 29, 2027 | MISSOURI STATE BEARS* | W 77-64 | 7-4 | T. Nelson 16 | C. Wallace 7 | M. Greer 8 |
| January 2, 2028 | @ Illinois State Redbirds* | W 89-81 | 8-4 | M. Greer 18 | C. Wallace 7 | D. Beck 7 |
| January 5, 2028 | @ Murray State Racers* | L 96-101 | 8-5 | T. Nelson 22 | C. Wallace 7 | O. Cotton 8 |
| January 9, 2028 | @ Valparaiso Beacons* | L 62-79 | 8-6 | J. Tan 12 | C. Wallace 4 | O. Cotton 11 |
| January 12, 2028 | ILLINOIS-CHICAGO FLAMES* | W 85-67 | 9-6 | M. Greer 21 | C. Wallace 10 | T. Armstead 6 |
| January 16, 2028 | @ Indiana State Sycamores* | L 56-72 | 9-7 | D. Beck 15 | C. Wallace 4 | T. Nelson 8 |
| January 19, 2028 | BELMONT BRUINS* | W 94-86 | 10-7 | M. Greer 18 | D. Ash 5 | D. Ash 7 |
| January 23, 2028 | NORTHERN IOWA PANTHERS* | L 63-84 | 10-8 | D. Beck 17 | C. Wallace 4 | M. Greer 7 |
| January 26, 2028 | INDIANA STATE SYCAMORES* | W 75-61 | 11-8 | M. Greer 22 | T. Nelson 6 | O. Cotton 11 |
| January 30, 2028 | @ Belmont Bruins* | L 70-91 | 11-9 | T. Nelson 13 | C. Wallace 5 | D. Beck 7 |
| February 2, 2028 | @ Northern Iowa Panthers* | W 89-86 | 12-9 | M. Greer 24 | C. Wallace 6 | O. Cotton 8 |
| February 6, 2028 | @ Illinois-Chicago Flames* | W 82-77 | 13-9 | T. Nelson 16 | C. Wallace 6 | T. Nelson 7 |
| February 9, 2028 | @ Drake Bulldogs* | W 75-64 | 14-9 | C. Wallace 21 | C. Wallace 5 | O. Cotton 8 |
| February 13, 2028 | ILLINOIS STATE REDBIRDS* | W 61-58 | 15-9 | T. Armstead 10 | C. Wallace 6 | D. Beck 7 |
| February 16, 2028 | MURRAY STATE RACERS* | L 82-100 | 15-10 | O. Cotton 16 | C. Wallace 5 | D. Beck 6 |
| February 20, 2028 | @ Evansville Purple Aces* | W 89-78 | 16-10 | T. Nelson 18 | C. Wallace 3 | T. Nelson 7 |
| February 23, 2028 | DRAKE BULLDOGS* | W 79-58 | 17-10 | J. Page 23 | C. Wallace 3 | O. Cotton 9 |
| February 27, 2028 | @ Missouri State Bears* | W 75-71 | 18-10 | O. Cotton 20 | C. Wallace 4 | T. Nelson 10 |
| March 2, 2028 | BRADLEY BRAVES* | W 78-74 | 19-10 | O. Cotton 19 | C. Wallace 7 | O. Cotton 9 |
| March 8, 2028 | ILLINOIS-CHICAGO FLAMES MVC Tournament | W 87-76 | 20-10 | M. Greer 22 | J. Page 4 | O. Cotton 9 |
| March 9, 2028 | @ Northern Iowa Panthers MVC Tournament | L 70-85 | 20-11 | J. Page 16 | J. Page 5 | M. Greer 8 |
