| November 15, 2027 | GEORGIA TECH YELLOW JACKETS | L 60-83 | 0-1 | B. Wilde 10 | M. Burns 4 | D. Lappas 9 |
| November 22, 2027 | TEXAS CHRISTIAN HORNED FROGS | W 89-79 | 1-1 | J. Thompson 29 | B. Wilde 7 | R. Whitfield 5 |
| November 25, 2027 | COLUMBIA LIONS | W 73-58 | 2-1 | S. Hamilton 16 | J. Thompson 4 | S. Hamilton 9 |
| November 29, 2027 | @ South Dakota State Jackrabbits | L 81-94 | 2-2 | J. Thompson 23 | B. Wilde 6 | J. Thompson 5 |
| December 2, 2027 | OREGON STATE BEAVERS | W 76-69 | 3-2 | J. Thompson 18 | B. Wilde 4 | J. Wallace 6 |
| December 6, 2027 | AUSTIN PEAY GOVERNORS | W 82-65 | 4-2 | D. Lappas 13 | B. Wilde 8 | D. Lappas 8 |
| December 13, 2027 | SOUTHERN ILLINOIS SALUKIS | L 79-89 | 4-3 | J. Thompson 23 | B. Wilde 10 | D. Lappas 7 |
| December 16, 2027 | MILWAUKEE PANTHERS Diamond Head Classic | W 85-75 | 5-3 | J. Thompson 30 | B. Wilde 7 | D. Lappas 8 |
| December 17, 2027 | @ Baylor Bears Diamond Head Classic | L 60-78 | 5-4 | J. Thompson 18 | B. Wilde 6 | D. Lappas 11 |
| December 20, 2027 | @ #9 Pittsburgh Panthers | L 68-88 | 5-5 | J. Thompson 18 | B. Wilde 6 | J. Thompson 5 |
| December 26, 2027 | @ #23 Michigan State Spartans* | L 68-71 | 5-6 | J. Thompson 21 | B. Wilde 6 | D. Lappas 7 |
| December 28, 2027 | PURDUE BOILERMAKERS* | L 61-66 | 5-7 | B. Wilde 14 | B. Wilde 3 | D. Lappas 11 |
| January 2, 2028 | @ Nebraska Cornhuskers* | W 80-76 | 6-7 | B. Wilde 17 | S. Hamilton 7 | D. Lappas 13 |
| January 4, 2028 | ILLINOIS FIGHTING ILLINI* | W 72-53 | 7-7 | J. Thompson 19 | B. Wilde 4 | J. Wallace 13 |
| January 9, 2028 | @ #3 Michigan Wolverines* | L 63-82 | 7-8 | J. Thompson 18 | B. Wilde 4 | D. Lappas 7 |
| January 11, 2028 | @ #13 Maryland Terrapins* | L 64-81 | 7-9 | D. Lappas 23 | J. Thompson 4 | D. Lappas 6 |
| January 16, 2028 | INDIANA HOOSIERS* | W 88-68 | 8-9 | J. Thompson 17 | B. Wilde 6 | D. Lappas 9 |
| January 18, 2028 | @ Southern California Trojans* | L 52-77 | 8-10 | B. Wilde 10 | B. Wilde 3 | D. Lappas 12 |
| January 23, 2028 | WASHINGTON HUSKIES* | L 73-78 | 8-11 | J. Thompson 21 | B. Wilde 9 | D. Lappas 7 |
| January 25, 2028 | OHIO STATE BUCKEYES* | W 75-62 | 9-11 | J. Thompson 17 | B. Wilde 5 | S. Hamilton 10 |
| January 30, 2028 | MINNESOTA GOLDEN GOPHERS* | L 74-81 | 9-12 | J. Thompson 18 | B. Wilde 3 | D. Lappas 11 |
| February 1, 2028 | @ Northwestern Wildcats* | L 62-76 | 9-13 | B. Wilde 23 | B. Wilde 3 | D. Lappas 12 |
| February 6, 2028 | @ #22 Wisconsin Badgers* | L 63-78 | 9-14 | J. Thompson 16 | B. Wilde 9 | R. Whitfield 6 |
| February 8, 2028 | OREGON DUCKS* | W 76-62 | 10-14 | J. Thompson 19 | D. Lappas 6 | D. Lappas 9 |
| February 13, 2028 | UCLA BRUINS* | L 71-77 | 10-15 | S. Hamilton 18 | B. Wilde 4 | D. Lappas 9 |
| February 15, 2028 | @ Iowa Hawkeyes* | L 86-97 | 10-16 | B. Wilde 15 | J. Thompson 4 | J. Wallace 6 |
| February 20, 2028 | @ Penn State Nittany Lions* | L 72-101 | 10-17 | J. Thompson 13 | J. Thompson 3 | D. Lappas 7 |
| February 22, 2028 | PENN STATE NITTANY LIONS* | W 80-72 | 11-17 | J. Thompson 25 | B. Wilde 5 | M. Burns 7 |
| February 27, 2028 | @ Ohio State Buckeyes* | L 87-96 OT | 11-18 | J. Thompson 27 | B. Wilde 8 | S. Hamilton 6 |
| March 1, 2028 | NORTHWESTERN WILDCATS* | W 73-61 | 12-18 | J. Thompson 17 | B. Wilde 7 | D. Lappas 11 |
