| November 16, 2027 | BOISE STATE BRONCOS | W 83-67 | 1-0 | S. Cleveland 18 | E. Owes 7 | G. Randle 10 |
| November 19, 2027 | @ Kansas State Wildcats | L 79-85 | 1-1 | T. Harrington 17 | E. Owes 7 | G. Williams 7 |
| November 21, 2027 | SAN FRANCISCO DONS WSSN Classic | W 78-65 | 2-1 | S. Cleveland 18 | G. Williams 6 | S. Cleveland 10 |
| November 22, 2027 | COLORADO STATE RAMS WSSN Classic | W 89-78 | 3-1 | G. Randle 17 | E. Owes 6 | S. Cleveland 10 |
| November 23, 2027 | #11 CONNECTICUT HUSKIES WSSN Classic | L 74-86 | 3-2 | E. Owes 21 | G. Randle 4 | G. Williams 9 |
| November 26, 2027 | WYOMING COWBOYS | W 71-64 | 4-2 | G. Williams 28 | T. Harrington 6 | G. Randle 9 |
| November 30, 2027 | NORTH CAROLINA TAR HEELS | W 101-88 | 5-2 | G. Williams 31 | S. Cleveland 6 | G. Williams 10 |
| December 3, 2027 | OAKLAND GOLDEN GRIZZLIES | W 80-63 | 6-2 | G. Williams 27 | E. Owes 6 | G. Williams 10 |
| December 7, 2027 | ILLINOIS STATE REDBIRDS | W 84-58 | 7-2 | S. Cleveland 17 | G. Williams 6 | G. Williams 14 |
| December 14, 2027 | MIDDLE TENNESSEE BLUE RAIDERS | W 79-61 | 8-2 | E. Owes 21 | E. Owes 6 | S. Cleveland 11 |
| December 21, 2027 | UC-IRVINE ANTEATERS | W 71-70 | 9-2 | G. Williams 20 | T. Harrington 5 | S. Cleveland 11 |
| December 26, 2027 | @ UCLA Bruins* | L 76-94 | 9-3 | G. Williams 24 | E. Owes 6 | S. Cleveland 9 |
| December 28, 2027 | @ #2 Michigan State Spartans* | L 82-95 | 9-4 | G. Williams 21 | E. Owes 8 | G. Williams 7 |
| January 2, 2028 | NORTHWESTERN WILDCATS* | W 78-59 | 10-4 | E. Owes 22 | T. Harrington 4 | G. Randle 10 |
| January 4, 2028 | OHIO STATE BUCKEYES* | W 83-81 | 11-4 | E. Owes 29 | E. Owes 3 | S. Cleveland 8 |
| January 9, 2028 | #14 OREGON DUCKS* | W 93-64 | 12-4 | G. Williams 30 | E. Owes 6 | G. Williams 12 |
| January 11, 2028 | RUTGERS SCARLET KNIGHTS* | W 95-76 | 13-4 | S. Cleveland 18 | E. Owes 9 | G. Williams 8 |
| January 16, 2028 | @ Indiana Hoosiers* | W 73-66 | 14-4 | G. Williams 30 | E. Owes 5 | G. Williams 11 |
| January 18, 2028 | PENN STATE NITTANY LIONS* | L 65-72 | 14-5 | G. Williams 26 | S. Cleveland 6 | G. Williams 9 |
| January 23, 2028 | NEBRASKA CORNHUSKERS* | W 85-77 | 15-5 | G. Williams 24 | E. Owes 8 | G. Williams 10 |
| January 25, 2028 | #5 WISCONSIN BADGERS* | L 80-85 | 15-6 | S. Cleveland 18 | G. Randle 6 | G. Williams 6 |
| January 30, 2028 | @ Minnesota Golden Gophers* | W 75-68 | 16-6 | G. Williams 19 | S. Cleveland 6 | S. Cleveland 10 |
| February 1, 2028 | @ #24 Iowa Hawkeyes* | W 93-91 OT | 17-6 | E. Owes 19 | E. Owes 7 | G. Williams 6 |
| February 6, 2028 | ILLINOIS FIGHTING ILLINI* | W 89-75 | 18-6 | S. Cleveland 26 | E. Owes 5 | G. Williams 13 |
| February 8, 2028 | @ Michigan Wolverines* | W 81-76 OT | 19-6 | E. Owes 23 | E. Owes 6 | G. Randle 9 |
| February 13, 2028 | @ Maryland Terrapins* | W 78-69 | 20-6 | G. Williams 21 | E. Owes 6 | G. Williams 10 |
| February 15, 2028 | WASHINGTON HUSKIES* | W 79-56 | 21-6 | G. Williams 21 | T. Harrington 5 | G. Williams 14 |
| February 20, 2028 | SOUTHERN CALIFORNIA TROJANS* | W 77-66 | 22-6 | G. Williams 19 | E. Owes 5 | G. Williams 12 |
| February 22, 2028 | @ Washington Huskies* | W 66-55 | 23-6 | G. Williams 15 | S. Cleveland 5 | S. Cleveland 10 |
| February 27, 2028 | @ #2 Wisconsin Badgers* | L 64-83 | 23-7 | G. Williams 13 | S. Cleveland 6 | G. Randle 6 |
| March 1, 2028 | @ Ohio State Buckeyes* | L 66-76 | 23-8 | G. Williams 22 | E. Owes 4 | E. Owes 3 |
| March 10, 2028 | TBD Big 10 Tournament | - | | | | |
