| November 15, 2027 | JACKSON STATE TIGERS | W 77-76 | 1-0 | C. Shepard 24 | R. Blossom 5 | C. Shepard 11 |
| November 18, 2027 | FAIRLEIGH DICKINSON KNIGHTS | W 92-73 | 2-0 | C. Shepard 29 | R. Sharpe 6 | C. Shepard 18 |
| November 22, 2027 | PRAIRIE VIEW PANTHERS | W 62-55 | 3-0 | C. Shepard 14 | R. Blossom 7 | C. Shepard 16 |
| November 25, 2027 | @ Kansas State Wildcats Myrtle Beach Invitational | W 73-64 | 4-0 | C. Shepard 24 | R. Blossom 5 | C. Shepard 10 |
| November 26, 2027 | @ Notre Dame Fighting Irish Myrtle Beach Invitational | W 84-76 | 5-0 | R. Sharpe 20 | R. Blossom 6 | C. Shepard 9 |
| November 27, 2027 | @ #14 VA Commonwealth Rams Myrtle Beach Invitational | W 90-54 | 6-0 | R. Sharpe 21 | R. Sharpe 4 | C. Shepard 9 |
| November 29, 2027 | #6 WEST VIRGINIA MOUNTAINEERS | L 67-84 | 6-1 | R. Sharpe 16 | R. Sharpe 2 | C. Shepard 12 |
| December 2, 2027 | #4 VIRGINIA CAVALIERS | L 60-86 | 6-2 | M. Woods 16 | R. Sharpe 4 | R. Sharpe 6 |
| December 6, 2027 | LOUISIANA-MONROE WARHAWKS | L 75-80 | 6-3 | R. Blossom 18 | R. Blossom 8 | C. Shepard 16 |
| December 13, 2027 | @ Rhode Island Rams | W 84-72 | 7-3 | R. Sharpe 24 | R. Sharpe 9 | I. Goode 9 |
| December 20, 2027 | GEORGIA TECH YELLOW JACKETS (8-1, 1-1 Away) | - | | | | |
| December 26, 2027 | @ Butler Bulldogs (6-4, 0-0, 2-1 Home)* | - | | | | |
| December 28, 2027 | CREIGHTON BLUE JAYS (8-2, 0-0, 0-0 Away)* | - | | | | |
| January 2, 2028 | @ Marquette Golden Eagles (10-1, 0-0, 5-1 Home)* | - | | | | |
| January 4, 2028 | ST. JOHNS RED STORM (4-4, 0-0, 1-1 Away)* | - | | | | |
| January 11, 2028 | SETON HALL PIRATES (9-1, 0-0, 1-0 Away)* | - | | | | |
| January 13, 2028 | @ Villanova Wildcats (7-0, 0-0, 4-0 Home)* | - | | | | |
| January 20, 2028 | CONNECTICUT HUSKIES (2-6, 0-0, 0-1 Away)* | - | | | | |
| January 23, 2028 | XAVIER MUSKETEERS (5-4, 0-0, 2-1 Away)* | - | | | | |
| January 27, 2028 | @ DePaul Blue Demons (6-2, 0-0, 5-0 Home)* | - | | | | |
| January 30, 2028 | @ Georgetown Hoyas (8-0, 0-0, 7-0 Home)* | - | | | | |
| February 1, 2028 | @ St. Johns Red Storm (4-4, 0-0, 3-2 Home)* | - | | | | |
| February 3, 2028 | VILLANOVA WILDCATS (7-0, 0-0, 3-0 Away)* | - | | | | |
| February 8, 2028 | @ Seton Hall Pirates (9-1, 0-0, 5-1 Home)* | - | | | | |
| February 13, 2028 | @ Creighton Blue Jays (8-2, 0-0, 6-1 Home)* | - | | | | |
| February 15, 2028 | DEPAUL BLUE DEMONS (6-2, 0-0, 1-2 Away)* | - | | | | |
| February 17, 2028 | GEORGETOWN HOYAS (8-0, 0-0, 1-0 Away)* | - | | | | |
| February 22, 2028 | @ Connecticut Huskies (2-6, 0-0, 1-4 Home)* | - | | | | |
| February 24, 2028 | @ Xavier Musketeers (5-4, 0-0, 2-2 Home)* | - | | | | |
| March 1, 2028 | BUTLER BULLDOGS (6-4, 0-0, 1-3 Away)* | - | | | | |
| March 3, 2028 | MARQUETTE GOLDEN EAGLES (10-1, 0-0, 1-0 Away)* | - | | | | |
