| November 13, 2027 | @ Mississippi State Bulldogs | W 82-72 | 1-0 | I. Wampler 17 | A. Brunson 5 | I. Wampler 12 |
| November 15, 2027 | @ Mississippi Valley Delta Devils | L 93-98 | 1-1 | J. Betts 18 | A. Brunson 6 | I. Wampler 5 |
| November 18, 2027 | @ #19 Creighton Blue Jays | L 73-81 | 1-2 | J. Betts 16 | J. Strong 3 | I. Wampler 6 |
| November 22, 2027 | VMI KEYDETS | W 92-75 | 2-2 | T. Danielson 24 | A. Brunson 4 | I. Wampler 9 |
| November 24, 2027 | UC-IRVINE ANTEATERS | L 72-75 | 2-3 | J. Betts 17 | J. Betts 5 | I. Wampler 12 |
| November 29, 2027 | @ Chattanooga Mocs | L 70-73 | 2-4 | T. Danielson 13 | A. Brunson 4 | I. Wampler 15 |
| December 2, 2027 | MCNEESE STATE COWBOYS | W 88-77 | 3-4 | J. Betts 17 | A. Brunson 6 | I. Wampler 7 |
| December 6, 2027 | @ Arizona State Sun Devils | L 73-88 | 3-5 | J. Betts 15 | A. Brunson 5 | I. Wampler 12 |
| December 9, 2027 | EVANSVILLE PURPLE ACES | W 91-86 | 4-5 | J. Betts 14 | A. Brunson 5 | I. Wampler 10 |
| December 13, 2027 | @ Drexel Dragons | W 90-73 | 5-5 | J. Betts 20 | A. Brunson 7 | I. Wampler 11 |
| December 16, 2027 | @ South Dakota State Jackrabbits | W 79-68 | 6-5 | J. Betts 18 | A. Brunson 5 | I. Wampler 11 |
| December 20, 2027 | @ Drake Bulldogs (4-5, 3-0 Home) | - | | | | |
| December 22, 2027 | @ Presbyterian Blue Hose (4-7, 3-2 Home) | - | | | | |
| December 26, 2027 | @ Richmond Spiders (7-2, 6-0 Home) | - | | | | |
| December 30, 2027 | SEATTLE REDHAWKS (3-6, 2-4 Away) | - | | | | |
| January 10, 2028 | @ Yale Bulldogs (6-5, 0-0, 2-1 Home)* | - | | | | |
| January 13, 2028 | PRINCETON TIGERS (5-6, 0-0, 4-4 Away)* | - | | | | |
| January 17, 2028 | @ Brown Bears (5-6, 0-0, 3-2 Home)* | - | | | | |
| January 20, 2028 | COLUMBIA LIONS (4-8, 0-0, 3-7 Away)* | - | | | | |
| January 24, 2028 | @ Harvard Crimson (6-4, 0-0, 4-0 Home)* | - | | | | |
| January 27, 2028 | DARTMOUTH BIG GREEN (4-8, 0-0, 1-6 Away)* | - | | | | |
| January 31, 2028 | @ Cornell Big Red (6-5, 0-0, 2-1 Home)* | - | | | | |
| February 3, 2028 | YALE BULLDOGS (6-5, 0-0, 4-3 Away)* | - | | | | |
| February 7, 2028 | @ Princeton Tigers (5-6, 0-0, 1-1 Home)* | - | | | | |
| February 10, 2028 | BROWN BEARS (5-6, 0-0, 2-4 Away)* | - | | | | |
| February 14, 2028 | @ Columbia Lions (4-8, 0-0, 1-1 Home)* | - | | | | |
| February 17, 2028 | HARVARD CRIMSON (6-4, 0-0, 2-4 Away)* | - | | | | |
| February 21, 2028 | @ Dartmouth Big Green (4-8, 0-0, 3-2 Home)* | - | | | | |
| February 24, 2028 | CORNELL BIG RED (6-5, 0-0, 4-4 Away)* | - | | | | |
