| November 17, 2027 | SO. CAROLINA UPSTATE SPARTANS | W 97-94 | 1-0 | L. Datcher 18 | J. Branch 4 | J. Branch 12 |
| November 21, 2027 | APPALACHIAN STATE MOUNTAINEERS Hall of Fame Classic | W 88-76 | 2-0 | J. Branch 26 | T. Marsh 8 | J. Branch 7 |
| November 22, 2027 | SAN DIEGO TOREROS Hall of Fame Classic | L 67-79 | 2-1 | J. Branch 20 | W. Hancock 4 | J. Branch 15 |
| November 24, 2027 | DAYTON FLYERS | L 79-80 | 2-2 | T. Marsh 14 | C. Shannon 4 | J. Branch 9 |
| December 1, 2027 | YOUNGSTOWN STATE PENGUINS | W 90-85 | 3-2 | B. Ellington 25 | T. Marsh 6 | L. Datcher 9 |
| December 6, 2027 | #6 VIRGINIA CAVALIERS | L 83-92 | 3-3 | C. Brewer 16 | T. Marsh 6 | J. Branch 10 |
| December 9, 2027 | HARVARD CRIMSON | W 82-69 | 4-3 | C. Shannon 23 | T. Marsh 8 | B. Ellington 11 |
| December 13, 2027 | @ #23 Seton Hall Pirates | L 67-86 | 4-4 | C. Shannon 19 | T. Marsh 4 | J. Branch 11 |
| December 16, 2027 | ORAL ROBERTS GOLDEN EAGLES | L 68-79 | 4-5 | L. Datcher 13 | C. Shannon 5 | J. Branch 9 |
| December 22, 2027 | EASTERN ILLINOIS PANTHERS | W 88-83 | 5-5 | T. Marsh 22 | C. Shannon 5 | L. Datcher 13 |
| December 26, 2027 | PURDUE BOILERMAKERS* | L 80-82 | 5-6 | J. Branch 25 | J. Branch 5 | J. Branch 9 |
| December 28, 2027 | NEBRASKA CORNHUSKERS* | W 93-83 | 6-6 | J. Branch 27 | J. Branch 5 | J. Branch 18 |
| January 2, 2028 | #23 MICHIGAN STATE SPARTANS* | L 75-85 | 6-7 | L. Datcher 24 | T. Marsh 9 | L. Datcher 10 |
| January 4, 2028 | @ Iowa Hawkeyes* | L 77-79 | 6-8 | T. Marsh 20 | B. Ellington 4 | B. Ellington 10 |
| January 9, 2028 | #18 WISCONSIN BADGERS* | L 63-88 | 6-9 | J. Branch 17 | J. Branch 3 | J. Branch 12 |
| January 11, 2028 | ILLINOIS FIGHTING ILLINI* | W 79-72 | 7-9 | J. Branch 19 | C. Shannon 4 | J. Branch 20 |
| January 16, 2028 | @ Ohio State Buckeyes* | L 73-83 | 7-10 | L. Datcher 18 | T. Marsh 5 | J. Branch 8 |
| January 18, 2028 | UCLA BRUINS* | W 92-55 | 8-10 | C. Shannon 26 | T. Marsh 6 | L. Datcher 13 |
| January 23, 2028 | @ Northwestern Wildcats* | L 69-80 | 8-11 | L. Datcher 14 | J. Branch 5 | J. Branch 13 |
| January 25, 2028 | MINNESOTA GOLDEN GOPHERS* | W 92-76 | 9-11 | C. Shannon 22 | T. Marsh 5 | C. Shannon 8 |
| January 30, 2028 | SOUTHERN CALIFORNIA TROJANS* | W 84-70 | 10-11 | C. Shannon 18 | T. Marsh 4 | L. Datcher 11 |
| February 1, 2028 | @ Penn State Nittany Lions* | L 61-75 | 10-12 | L. Datcher 15 | T. Marsh 4 | L. Datcher 17 |
| February 6, 2028 | @ Washington Huskies* | L 57-87 | 10-13 | C. Shannon 16 | T. Marsh 3 | L. Datcher 7 |
| February 8, 2028 | @ Rutgers Scarlet Knights* | L 62-76 | 10-14 | J. Branch 21 | S. Young 7 | J. Branch 12 |
| February 13, 2028 | @ Indiana Hoosiers* | W 84-71 | 11-14 | T. Marsh 12 | T. Marsh 4 | L. Datcher 11 |
| February 15, 2028 | @ #12 Maryland Terrapins* | L 49-66 | 11-15 | L. Datcher 9 | C. Brewer 3 | B. Ellington 8 |
| February 20, 2028 | #3 MICHIGAN WOLVERINES* | L 60-66 | 11-16 | J. Branch 16 | L. Datcher 3 | L. Datcher 10 |
| February 22, 2028 | #12 MARYLAND TERRAPINS* | L 68-76 | 11-17 | C. Brewer 13 | T. Marsh 4 | J. Branch 7 |
| February 27, 2028 | @ Minnesota Golden Gophers* | L 72-84 | 11-18 | C. Shannon 23 | S. Young 5 | B. Ellington 9 |
| March 1, 2028 | @ #3 Michigan Wolverines* | L 40-78 | 11-19 | C. Shannon 9 | J. Branch 3 | J. Branch 9 |
