| November 17, 2027 | SO. CAROLINA UPSTATE SPARTANS | W 97-94 | 1-0 | L. Datcher 18 | J. Branch 4 | J. Branch 12 |
| November 21, 2027 | APPALACHIAN STATE MOUNTAINEERS Hall of Fame Classic | W 88-76 | 2-0 | J. Branch 26 | T. Marsh 8 | J. Branch 7 |
| November 22, 2027 | SAN DIEGO TOREROS Hall of Fame Classic | L 67-79 | 2-1 | J. Branch 20 | W. Hancock 4 | J. Branch 15 |
| November 24, 2027 | DAYTON FLYERS | L 79-80 | 2-2 | T. Marsh 14 | C. Shannon 4 | J. Branch 9 |
| December 1, 2027 | YOUNGSTOWN STATE PENGUINS | W 90-85 | 3-2 | B. Ellington 25 | T. Marsh 6 | L. Datcher 9 |
| December 6, 2027 | #6 VIRGINIA CAVALIERS | L 83-92 | 3-3 | C. Brewer 16 | T. Marsh 6 | J. Branch 10 |
| December 9, 2027 | HARVARD CRIMSON | W 82-69 | 4-3 | C. Shannon 23 | T. Marsh 8 | B. Ellington 11 |
| December 13, 2027 | @ #23 Seton Hall Pirates | L 67-86 | 4-4 | C. Shannon 19 | T. Marsh 4 | J. Branch 11 |
| December 16, 2027 | ORAL ROBERTS GOLDEN EAGLES | L 68-79 | 4-5 | L. Datcher 13 | C. Shannon 5 | J. Branch 9 |
| December 22, 2027 | EASTERN ILLINOIS PANTHERS (1-7, 0-6 Away) | - | | | | |
| December 26, 2027 | PURDUE BOILERMAKERS (6-3, 0-0, 0-0 Away)* | - | | | | |
| December 28, 2027 | NEBRASKA CORNHUSKERS (4-4, 0-0, 0-1 Away)* | - | | | | |
| January 2, 2028 | MICHIGAN STATE SPARTANS (6-1, 0-0, 1-1 Away)* | - | | | | |
| January 4, 2028 | @ Iowa Hawkeyes (3-5, 0-0, 3-2 Home)* | - | | | | |
| January 9, 2028 | WISCONSIN BADGERS (6-2, 0-0, 1-1 Away)* | - | | | | |
| January 11, 2028 | ILLINOIS FIGHTING ILLINI (6-3, 0-0, 0-1 Away)* | - | | | | |
| January 16, 2028 | @ Ohio State Buckeyes (6-3, 0-0, 4-0 Home)* | - | | | | |
| January 18, 2028 | UCLA BRUINS (8-2, 0-0, 1-0 Away)* | - | | | | |
| January 23, 2028 | @ Northwestern Wildcats (5-3, 0-0, 5-1 Home)* | - | | | | |
| January 25, 2028 | MINNESOTA GOLDEN GOPHERS (7-3, 0-0, 0-2 Away)* | - | | | | |
| January 30, 2028 | SOUTHERN CALIFORNIA TROJANS (5-3, 0-0, 0-0 Away)* | - | | | | |
| February 1, 2028 | @ Penn State Nittany Lions (3-4, 0-0, 3-3 Home)* | - | | | | |
| February 6, 2028 | @ Washington Huskies (5-3, 0-0, 5-2 Home)* | - | | | | |
| February 8, 2028 | @ Rutgers Scarlet Knights (5-4, 0-0, 4-2 Home)* | - | | | | |
| February 13, 2028 | @ Indiana Hoosiers (4-4, 0-0, 3-1 Home)* | - | | | | |
| February 15, 2028 | @ Maryland Terrapins (6-2, 0-0, 5-0 Home)* | - | | | | |
| February 20, 2028 | MICHIGAN WOLVERINES (10-0, 0-0, 0-0 Away)* | - | | | | |
| February 22, 2028 | MARYLAND TERRAPINS (6-2, 0-0, 0-1 Away)* | - | | | | |
| February 27, 2028 | @ Minnesota Golden Gophers (7-3, 0-0, 5-0 Home)* | - | | | | |
| March 1, 2028 | @ Michigan Wolverines (10-0, 0-0, 7-0 Home)* | - | | | | |
