| November 14, 2027 | @ Southern Methodist Mustangs | L 66-86 | 0-1 | D. Chapman 15 | J. Cobb 4 | D. Chapman 9 |
| November 18, 2027 | @ #7 Louisville Cardinals | L 63-80 | 0-2 | J. Cobb 12 | J. Chatman 7 | E. Hancock 7 |
| November 21, 2027 | @ Missouri Tigers WSSN Classic | L 59-71 | 0-3 | J. Best 14 | J. Chatman 3 | J. Cobb 10 |
| November 24, 2027 | @ Grambling Tigers | W 87-76 | 1-3 | J. Chatman 22 | J. Chatman 8 | J. Best 7 |
| November 29, 2027 | @ Florida State Seminoles | L 68-74 | 1-4 | J. Chatman 13 | J. Chatman 6 | D. Chapman 9 |
| December 1, 2027 | @ California Baptist Lancers | W 85-77 | 2-4 | J. Chatman 18 | J. Cobb 6 | D. Lofton 6 |
| December 5, 2027 | MASSACHUSETTS MINUTEMEN | W 84-72 | 3-4 | E. Hancock 22 | J. Chatman 8 | E. Hancock 10 |
| December 8, 2027 | ORAL ROBERTS GOLDEN EAGLES | W 72-51 | 4-4 | E. Hancock 16 | J. Chatman 5 | E. Hancock 9 |
| December 21, 2027 | SIENA SAINTS | W 81-66 | 5-4 | D. Chapman 18 | J. Cobb 4 | E. Hancock 8 |
| December 26, 2027 | @ Akron Zips* | L 68-89 | 5-5 | D. Lofton 13 | J. Chatman 3 | J. Cobb 5 |
| December 29, 2027 | @ Western Michigan Broncos* | L 76-81 | 5-6 | D. Lofton 24 | J. Cobb 8 | E. Hancock 7 |
| January 2, 2028 | EASTERN MICHIGAN EAGLES* | L 61-68 | 5-7 | D. Lofton 12 | J. Chatman 6 | E. Hancock 8 |
| January 5, 2028 | NORTHERN ILLINOIS HUSKIES* | L 62-69 | 5-8 | D. Chapman 13 | J. Chatman 5 | D. Chapman 9 |
| January 9, 2028 | MIAMI (OH) REDHAWKS* | W 72-64 | 6-8 | J. Cobb 15 | D. Lofton 5 | D. Lofton 8 |
| January 12, 2028 | @ Buffalo Bulls* | L 54-67 | 6-9 | E. Hancock 13 | J. Chatman 6 | D. Chapman 9 |
| January 16, 2028 | @ Central Michigan Chippewas* | L 69-79 | 6-10 | D. Chapman 14 | J. Chatman 3 | J. Cobb 7 |
| January 19, 2028 | TOLEDO ROCKETS* | W 88-75 | 7-10 | E. Hancock 30 | J. Cobb 4 | E. Hancock 9 |
| January 23, 2028 | KENT STATE GOLDEN FLASHES* | W 81-64 | 8-10 | D. Lofton 18 | J. Cobb 6 | E. Hancock 9 |
| January 26, 2028 | @ Ball State Cardinals* | L 68-75 | 8-11 | D. Chapman 13 | J. Cobb 4 | E. Hancock 12 |
| January 30, 2028 | @ Toledo Rockets* | W 71-63 | 9-11 | E. Hancock 20 | J. Chatman 5 | D. Chapman 9 |
| February 2, 2028 | @ Kent State Golden Flashes* | L 65-84 | 9-12 | E. Hancock 12 | J. Chatman 6 | J. Cobb 6 |
| February 6, 2028 | BUFFALO BULLS* | W 78-64 | 10-12 | E. Hancock 12 | J. Chatman 5 | D. Chapman 10 |
| February 9, 2028 | CENTRAL MICHIGAN CHIPPEWAS* | W 83-81 | 11-12 | D. Chapman 19 | E. Hancock 8 | J. Cobb 9 |
| February 13, 2028 | @ Eastern Michigan Eagles* | W 76-69 | 12-12 | E. Hancock 22 | D. Chapman 4 | J. Cobb 13 |
| February 16, 2028 | @ Northern Illinois Huskies* | L 80-93 | 12-13 | E. Hancock 23 | J. Chatman 5 | D. Lofton 5 |
| February 20, 2028 | AKRON ZIPS* | L 57-68 | 12-14 | J. Best 14 | J. Chatman 5 | E. Hancock 6 |
| February 23, 2028 | WESTERN MICHIGAN BRONCOS* | W 74-70 | 13-14 | J. Chatman 15 | J. Chatman 4 | E. Hancock 9 |
| February 27, 2028 | BALL STATE CARDINALS* | L 82-88 | 13-15 | D. Lofton 15 | D. Lofton 3 | E. Hancock 11 |
| March 2, 2028 | @ Bowling Green State Falcons* | L 64-82 | 13-16 | J. Chatman 15 | D. Lofton 2 | D. Chapman 11 |
| March 7, 2028 | @ Buffalo Bulls MAC Tournament | L 59-62 | 13-17 | J. Chatman 22 | J. Cobb 7 | D. Chapman 10 |
