| November 13, 2027 | SOUTH DAKOTA STATE JACKRABBITS Legends Classic | W 78-73 | 1-0 | B. Everett 20 | D. Bailey 9 | C. Raymond 7 |
| November 15, 2027 | @ #20 Pittsburgh Panthers Legends Classic | L 64-73 | 1-1 | C. Raymond 15 | B. Everett 2 | C. Raymond 11 |
| November 22, 2027 | UTAH VALLEY WOLVERINES | W 79-68 | 2-1 | D. Delea 15 | D. Bailey 5 | C. Raymond 9 |
| November 25, 2027 | @ Arizona State Sun Devils | W 76-74 | 3-1 | C. Raymond 14 | D. Bailey 4 | C. Raymond 16 |
| November 27, 2027 | @ Houston Cougars | L 64-86 | 3-2 | D. Gilbert 11 | D. Bailey 8 | C. Raymond 14 |
| November 29, 2027 | QUINNIPIAC BOBCATS | W 83-66 | 4-2 | P. Johnson 16 | D. Bailey 7 | M. Perkins 7 |
| December 2, 2027 | LOUISIANA-MONROE WARHAWKS | W 93-80 | 5-2 | D. Gilbert 18 | D. Bailey 5 | C. Raymond 16 |
| December 6, 2027 | @ #3 North Carolina Tar Heels | L 60-85 | 5-3 | D. Delea 16 | P. Johnson 5 | L. Worley 6 |
| December 13, 2027 | FLORIDA INTERNATIONAL PANTHERS | W 74-63 | 6-3 | B. Everett 14 | D. Bailey 8 | C. Raymond 10 |
| December 20, 2027 | MOUNT ST. MARYS MOUNTAINEERS | W 76-70 | 7-3 | C. Raymond 15 | D. Bailey 3 | C. Raymond 11 |
| December 26, 2027 | #3 MICHIGAN WOLVERINES* | L 67-84 | 7-4 | B. Everett 16 | P. Johnson 5 | C. Raymond 6 |
| December 28, 2027 | @ #20 Wisconsin Badgers* | L 68-80 | 7-5 | D. Delea 18 | D. Bailey 6 | C. Raymond 5 |
| January 2, 2028 | PENN STATE NITTANY LIONS* | L 66-73 | 7-6 | D. Bailey 13 | D. Bailey 4 | M. Perkins 9 |
| January 4, 2028 | NEBRASKA CORNHUSKERS* | W 88-65 | 8-6 | D. Gilbert 17 | D. Bailey 5 | C. Raymond 10 |
| January 9, 2028 | @ Illinois Fighting Illini* | L 61-73 | 8-7 | B. Everett 12 | D. Bailey 2 | C. Raymond 10 |
| January 11, 2028 | @ Purdue Boilermakers* | L 63-83 | 8-8 | M. Perkins 18 | D. Bailey 7 | C. Raymond 9 |
| January 16, 2028 | OREGON DUCKS* | W 83-73 | 9-8 | D. Gilbert 13 | D. Bailey 5 | C. Raymond 11 |
| January 18, 2028 | @ Iowa Hawkeyes* | L 73-80 | 9-9 | S. Waterman 23 | D. Gilbert 3 | S. Waterman 7 |
| January 23, 2028 | INDIANA HOOSIERS* | W 60-51 | 10-9 | B. Everett 15 | D. Gilbert 3 | M. Perkins 11 |
| January 25, 2028 | @ Rutgers Scarlet Knights* | L 62-75 | 10-10 | C. Raymond 18 | D. Bailey 4 | C. Raymond 12 |
| January 30, 2028 | WASHINGTON HUSKIES* | L 58-64 | 10-11 | M. Perkins 16 | D. Delea 5 | C. Raymond 9 |
| February 1, 2028 | SOUTHERN CALIFORNIA TROJANS* | L 74-89 | 10-12 | D. Delea 13 | D. Bailey 3 | C. Raymond 12 |
| February 6, 2028 | @ UCLA Bruins* | W 78-70 | 11-12 | D. Gilbert 16 | M. Perkins 4 | S. Waterman 8 |
| February 8, 2028 | NORTHWESTERN WILDCATS* | W 86-65 | 12-12 | B. Everett 21 | C. Raymond 6 | C. Raymond 13 |
| February 13, 2028 | @ Minnesota Golden Gophers* | W 86-78 | 13-12 | D. Delea 19 | D. Bailey 2 | M. Perkins 8 |
| February 15, 2028 | MICHIGAN STATE SPARTANS* | L 60-69 | 13-13 | C. Raymond 9 | D. Bailey 4 | C. Raymond 14 |
| February 20, 2028 | @ #12 Maryland Terrapins* | W 63-57 | 14-13 | D. Bailey 14 | D. Bailey 3 | C. Raymond 9 |
| February 22, 2028 | @ Northwestern Wildcats* | W 64-49 | 15-13 | S. Waterman 17 | D. Bailey 10 | C. Raymond 12 |
| February 27, 2028 | RUTGERS SCARLET KNIGHTS* | W 96-87 OT | 16-13 | C. Raymond 23 | B. Everett 6 | C. Raymond 17 |
| March 1, 2028 | @ Penn State Nittany Lions* | W 89-78 | 17-13 | B. Everett 18 | D. Bailey 4 | C. Raymond 16 |
| March 9, 2028 | @ Illinois Fighting Illini Big 10 Tournament | W 63-59 | 18-13 | M. Perkins 11 | D. Bailey 4 | S. Waterman 9 |
| March 10, 2028 | @ #3 Michigan Wolverines Big 10 Tournament | L 54-75 | 18-14 | D. Delea 10 | D. Bailey 4 | C. Raymond 10 |