| November 16, 2027 | EAST TEXAS A&M LIONS | L 67-79 | 0-1 | J. Cook 13 | D. Banks 4 | Q. Blackwell 5 |
| November 19, 2027 | @ Utah Utes | W 81-64 | 1-1 | R. Jensen 13 | D. Banks 7 | D. Horvath 12 |
| November 23, 2027 | SOUTH FLORIDA BULLS | W 79-68 | 2-1 | D. Horvath 18 | D. Banks 6 | R. Jensen 4 |
| November 25, 2027 | SAM HOUSTON STATE BEARKATS Myrtle Beach Invitational | W 83-62 | 3-1 | D. Banks 14 | D. Banks 4 | J. Simmons 9 |
| November 26, 2027 | WAKE FOREST DEMON DEACONS Myrtle Beach Invitational | L 86-89 | 3-2 | R. Jensen 18 | D. Banks 3 | R. Jensen 5 |
| November 28, 2027 | JACKSONVILLE DOLPHINS | W 88-68 | 4-2 | J. Simmons 14 | D. Banks 4 | D. Horvath 9 |
| December 3, 2027 | TEXAS STATE BOBCATS | W 93-91 | 5-2 | D. Horvath 23 | R. Jensen 6 | J. Simmons 7 |
| December 7, 2027 | JACKSONVILLE STATE GAMECOCKS | W 76-63 | 6-2 | R. Jensen 18 | D. Banks 4 | J. Simmons 12 |
| December 14, 2027 | TENNESSEE STATE TIGERS | W 96-86 | 7-2 | J. Simmons 14 | D. Banks 9 | Q. Blackwell 7 |
| December 21, 2027 | @ #23 Vanderbilt Commodores | L 69-98 | 7-3 | J. Simmons 13 | R. Jensen 5 | J. Simmons 6 |
| December 26, 2027 | @ #2 Michigan State Spartans* | L 70-74 | 7-4 | J. Simmons 16 | D. Banks 5 | D. Horvath 10 |
| December 28, 2027 | NORTHWESTERN WILDCATS* | W 107-74 | 8-4 | J. Cook 25 | D. Horvath 4 | Q. Blackwell 6 |
| January 2, 2028 | @ UCLA Bruins* | L 79-89 | 8-5 | D. Banks 17 | D. Banks 7 | R. Jensen 6 |
| January 4, 2028 | WASHINGTON HUSKIES* | W 97-88 | 9-5 | R. Jensen 17 | D. Banks 5 | D. Horvath 7 |
| January 9, 2028 | @ #6 Wisconsin Badgers* | L 63-80 | 9-6 | R. Jensen 13 | D. Banks 4 | J. Simmons 4 |
| January 11, 2028 | OHIO STATE BUCKEYES* | L 65-97 | 9-7 | D. Horvath 11 | J. Brown 3 | J. Simmons 8 |
| January 16, 2028 | #24 MICHIGAN WOLVERINES* | W 101-86 | 10-7 | D. Banks 21 | D. Banks 5 | J. Simmons 12 |
| January 18, 2028 | SOUTHERN CALIFORNIA TROJANS* | W 82-71 | 11-7 | D. Grace 17 | D. Banks 3 | Q. Blackwell 7 |
| January 23, 2028 | @ #14 Purdue Boilermakers* | L 77-85 | 11-8 | R. Jensen 12 | J. Brown 5 | D. Banks 4 |
| January 25, 2028 | MARYLAND TERRAPINS* | L 69-76 | 11-9 | D. Banks 23 | R. Shannon 4 | J. Simmons 8 |
| January 30, 2028 | @ Indiana Hoosiers* | L 71-84 | 11-10 | M. Enyiazu 14 | D. Banks 7 | R. Jensen 5 |
| February 1, 2028 | @ Penn State Nittany Lions* | L 69-80 | 11-11 | D. Grace 18 | D. Banks 8 | D. Horvath 7 |
| February 6, 2028 | @ Minnesota Golden Gophers* | W 76-73 | 12-11 | D. Grace 18 | D. Banks 7 | D. Horvath 10 |
| February 8, 2028 | @ Illinois Fighting Illini* | L 69-90 | 12-12 | J. Simmons 14 | R. Jensen 5 | D. Grace 6 |
| February 13, 2028 | IOWA HAWKEYES* | W 95-87 | 13-12 | D. Grace 15 | D. Banks 7 | J. Simmons 9 |
| February 15, 2028 | RUTGERS SCARLET KNIGHTS* | W 109-94 | 14-12 | D. Banks 19 | D. Banks 6 | Q. Blackwell 6 |
| February 20, 2028 | #24 OREGON DUCKS* | L 85-102 | 14-13 | R. Jensen 19 | D. Banks 4 | J. Brown 8 |
| February 22, 2028 | @ Michigan Wolverines* | W 75-66 | 15-13 | R. Jensen 18 | D. Banks 5 | J. Simmons 12 |
| February 27, 2028 | #4 MICHIGAN STATE SPARTANS* | L 82-92 | 15-14 | R. Jensen 18 | D. Banks 4 | J. Simmons 7 |
| March 1, 2028 | @ Iowa Hawkeyes* | L 82-105 | 15-15 | D. Horvath 17 | J. Cook 5 | J. Simmons 8 |
| March 8, 2028 | @ Penn State Nittany Lions (12-17, 9-8 Home) Big 10 Tournament | - | | | | |
