| November 15, 2027 | TEXAS-SAN ANTONIO ROADRUNNERS | W 75-47 | 1-0 | E. Kresse 18 | P. Bell 4 | E. Kresse 18 |
| November 18, 2027 | SIENA SAINTS | W 71-63 | 2-0 | M. Trilli 17 | L. Dawson 7 | E. Kresse 7 |
| November 22, 2027 | LA SALLE EXPLORERS | W 75-49 | 3-0 | P. Dye 16 | P. Bell 5 | E. Kresse 7 |
| November 25, 2027 | VERMONT CATAMOUNTS Myrtle Beach Invitational | W 66-55 | 4-0 | B. Spears 17 | P. Bell 5 | E. Kresse 11 |
| November 26, 2027 | PROVIDENCE FRIARS Myrtle Beach Invitational | L 76-84 | 4-1 | B. Spears 14 | P. Bell 5 | D. Patton 5 |
| November 29, 2027 | TEXAS A&M-CC ISLANDERS | L 81-84 OT | 4-2 | D. Patton 25 | P. Bell 7 | E. Kresse 14 |
| December 2, 2027 | SOUTH ALABAMA JAGUARS | W 68-54 | 5-2 | L. Dawson 17 | R. Wilson 6 | D. Patton 11 |
| December 6, 2027 | DELAWARE FIGHTIN' BLUE HENS | L 56-60 | 5-3 | D. Patton 14 | R. Wilson 4 | E. Kresse 12 |
| December 13, 2027 | MOREHEAD STATE EAGLES | L 51-64 | 5-4 | D. Patton 10 | L. Dawson 5 | D. Patton 10 |
| December 20, 2027 | @ Texas Christian Horned Frogs | L 72-79 | 5-5 | P. Bell 17 | P. Bell 5 | E. Kresse 10 |
| December 26, 2027 | @ NC-State Wolfpack* | W 70-67 | 6-5 | P. Bell 17 | E. Kresse 4 | D. Patton 7 |
| December 28, 2027 | @ Syracuse Orange* | W 82-75 | 7-5 | M. Trilli 18 | L. Dawson 6 | E. Kresse 15 |
| January 2, 2028 | #14 PITTSBURGH PANTHERS* | W 80-76 | 8-5 | D. Patton 15 | R. Wilson 5 | E. Kresse 11 |
| January 4, 2028 | @ #11 Louisville Cardinals* | L 74-83 | 8-6 | B. Spears 18 | L. Dawson 4 | B. Spears 8 |
| January 9, 2028 | @ Clemson Tigers* | W 78-67 | 9-6 | B. Spears 25 | L. Dawson 5 | E. Kresse 9 |
| January 11, 2028 | GEORGIA TECH YELLOW JACKETS* | W 91-76 | 10-6 | B. Spears 13 | L. Dawson 6 | B. Spears 6 |
| January 16, 2028 | @ California Golden Bears* | W 85-77 OT | 11-6 | T. Midgley 15 | R. Wilson 3 | E. Kresse 8 |
| January 18, 2028 | @ #8 Duke Blue Devils* | L 67-86 | 11-7 | B. Spears 16 | P. Bell 4 | E. Kresse 12 |
| January 23, 2028 | @ Boston College Eagles* | L 63-87 | 11-8 | P. Bell 9 | P. Dye 3 | E. Kresse 6 |
| January 25, 2028 | @ Southern Methodist Mustangs* | W 70-64 | 12-8 | D. Patton 11 | E. Kresse 3 | E. Kresse 8 |
| January 30, 2028 | FLORIDA STATE SEMINOLES* | W 68-56 | 13-8 | E. Kresse 12 | L. Dawson 4 | E. Kresse 13 |
| February 1, 2028 | #8 VIRGINIA CAVALIERS* | W 82-66 | 14-8 | B. Spears 20 | R. Wilson 6 | E. Kresse 10 |
| February 6, 2028 | VIRGINIA TECH HOKIES* | W 88-71 | 15-8 | D. Watkins 16 | P. Bell 9 | D. Patton 6 |
| February 8, 2028 | @ Miami (FL) Hurricanes* | L 59-74 | 15-9 | D. Patton 15 | P. Bell 3 | E. Kresse 13 |
| February 13, 2028 | #10 NORTH CAROLINA TAR HEELS* | L 65-68 | 15-10 | D. Patton 13 | P. Bell 5 | E. Kresse 15 |
| February 15, 2028 | STANFORD CARDINAL* | W 69-62 | 16-10 | E. Kresse 16 | P. Bell 6 | E. Kresse 8 |
| February 20, 2028 | @ Wake Forest Demon Deacons* | L 83-98 | 16-11 | B. Spears 24 | P. Bell 9 | D. Patton 5 |
| February 22, 2028 | NC-STATE WOLFPACK* | W 79-66 | 17-11 | E. Kresse 16 | P. Bell 5 | E. Kresse 10 |
| February 27, 2028 | SOUTHERN METHODIST MUSTANGS* | W 102-88 | 18-11 | D. Patton 19 | P. Bell 6 | E. Kresse 8 |
| March 1, 2028 | #9 DUKE BLUE DEVILS* | W 64-61 | 19-11 | T. Midgley 16 | P. Bell 6 | E. Kresse 11 |
| March 10, 2028 | #9 VIRGINIA CAVALIERS ACC Tournament | L 53-65 | 19-12 | P. Dye 11 | L. Dawson 6 | E. Kresse 10 |
