| November 16, 2027 | LOUISIANA-LAFAYETTE RAGIN' CAJUNS | W 73-68 | 1-0 | L. Hahn 18 | R. Everhart 4 | L. Hahn 7 |
| November 18, 2027 | RICHMOND SPIDERS Sunshine Slam | W 81-56 | 2-0 | R. Everhart 18 | W. Muckle 4 | R. Everhart 10 |
| November 19, 2027 | WASHINGTON HUSKIES Sunshine Slam | W 85-65 | 3-0 | R. Everhart 20 | R. Claxton 5 | R. Everhart 9 |
| November 20, 2027 | @ #1 Kansas Jayhawks Sunshine Slam | L 44-72 | 3-1 | L. Hahn 12 | R. Claxton 4 | L. Hahn 4 |
| November 23, 2027 | ST. THOMAS TOMMIES | W 86-78 | 4-1 | L. Hahn 16 | L. Hahn 5 | J. Sanders 7 |
| November 30, 2027 | WEBER STATE WILDCATS | W 84-72 | 5-1 | R. Claxton 22 | L. Hahn 5 | W. Muckle 10 |
| December 3, 2027 | @ Minnesota Golden Gophers | L 69-78 | 5-2 | W. Muckle 14 | R. Claxton 4 | W. Muckle 11 |
| December 7, 2027 | LIBERTY FLAMES | W 79-60 | 6-2 | L. Hahn 26 | R. Claxton 13 | J. Sanders 9 |
| December 10, 2027 | @ Rutgers Scarlet Knights | W 81-69 | 7-2 | L. Hahn 27 | R. Claxton 6 | W. Muckle 8 |
| December 14, 2027 | GREEN BAY PHOENIX | L 74-85 | 7-3 | L. Hahn 13 | L. Hahn 3 | J. Sanders 9 |
| December 21, 2027 | @ Iowa Hawkeyes | L 66-86 | 7-4 | J. Sanders 16 | R. Claxton 3 | J. Sanders 9 |
| December 26, 2027 | @ #12 Louisville Cardinals* | L 62-90 | 7-5 | W. Muckle 11 | L. Hahn 5 | W. Muckle 7 |
| December 28, 2027 | #1 DUKE BLUE DEVILS* | L 73-87 | 7-6 | L. Hahn 30 | R. Claxton 5 | W. Muckle 5 |
| January 2, 2028 | @ California Golden Bears* | L 66-85 | 7-7 | L. Hahn 20 | R. Everhart 5 | W. Muckle 7 |
| January 4, 2028 | @ Florida State Seminoles* | W 74-72 | 8-7 | J. Sanders 23 | R. Claxton 5 | L. Hahn 7 |
| January 9, 2028 | @ #10 Virginia Cavaliers* | L 76-98 | 8-8 | J. Sanders 16 | R. Claxton 4 | J. Sanders 8 |
| January 11, 2028 | @ #21 Syracuse Orange* | L 57-71 | 8-9 | L. Hahn 13 | L. Hahn 5 | J. Sanders 6 |
| January 16, 2028 | CLEMSON TIGERS* | W 65-59 | 9-9 | L. Hahn 17 | R. Claxton 5 | J. Sanders 8 |
| January 18, 2028 | @ Virginia Tech Hokies* | L 60-69 | 9-10 | R. Claxton 12 | R. Claxton 6 | J. Sanders 6 |
| January 23, 2028 | @ Pittsburgh Panthers* | W 79-70 | 10-10 | L. Hahn 18 | R. Claxton 8 | W. Muckle 9 |
| January 25, 2028 | NC-STATE WOLFPACK* | W 58-48 | 11-10 | L. Hahn 14 | L. Hahn 4 | R. Everhart 9 |
| January 30, 2028 | SOUTHERN METHODIST MUSTANGS* | W 95-78 | 12-10 | L. Hahn 27 | L. Hahn 6 | W. Muckle 10 |
| February 1, 2028 | MIAMI (FL) HURRICANES* | L 65-71 | 12-11 | L. Hahn 23 | R. Claxton 3 | R. Everhart 6 |
| February 6, 2028 | @ Stanford Cardinal* | L 70-80 | 12-12 | R. Everhart 23 | R. Everhart 5 | R. Everhart 6 |
| February 8, 2028 | GEORGIA TECH YELLOW JACKETS* | W 76-72 | 13-12 | L. Hahn 19 | R. Claxton 4 | W. Muckle 9 |
| February 13, 2028 | NORTH CAROLINA TAR HEELS* | W 81-65 | 14-12 | J. Sanders 19 | L. Hahn 5 | J. Sanders 10 |
| February 15, 2028 | @ Wake Forest Demon Deacons* | W 85-75 | 15-12 | R. Claxton 28 | W. Muckle 6 | S. Armstrong 7 |
| February 20, 2028 | BOSTON COLLEGE EAGLES* | L 69-73 | 15-13 | L. Hahn 26 | R. Claxton 5 | L. Hahn 8 |
| February 22, 2028 | @ Boston College Eagles* | W 102-99 OT | 16-13 | L. Hahn 35 | J. Tiago 10 | J. Sanders 10 |
| February 27, 2028 | FLORIDA STATE SEMINOLES* | W 81-69 | 17-13 | R. Everhart 16 | L. Hahn 4 | R. Everhart 6 |
| March 1, 2028 | CALIFORNIA GOLDEN BEARS* | L 68-70 | 17-14 | R. Claxton 25 | L. Hahn 5 | S. Armstrong 7 |
| March 9, 2028 | CLEMSON TIGERS (19-12, 2-10 Away) ACC Tournament | - | | | | |
