| November 15, 2027 | TEXAS-SAN ANTONIO ROADRUNNERS | W 75-47 | 1-0 | E. Kresse 18 | P. Bell 4 | E. Kresse 18 |
| November 18, 2027 | SIENA SAINTS | W 71-63 | 2-0 | M. Trilli 17 | L. Dawson 7 | E. Kresse 7 |
| November 22, 2027 | LA SALLE EXPLORERS | W 75-49 | 3-0 | P. Dye 16 | P. Bell 5 | E. Kresse 7 |
| November 25, 2027 | VERMONT CATAMOUNTS Myrtle Beach Invitational | W 66-55 | 4-0 | B. Spears 17 | P. Bell 5 | E. Kresse 11 |
| November 26, 2027 | PROVIDENCE FRIARS Myrtle Beach Invitational | L 76-84 | 4-1 | B. Spears 14 | P. Bell 5 | D. Patton 5 |
| November 29, 2027 | TEXAS A&M-CC ISLANDERS | L 81-84 OT | 4-2 | D. Patton 25 | P. Bell 7 | E. Kresse 14 |
| December 2, 2027 | SOUTH ALABAMA JAGUARS | W 68-54 | 5-2 | L. Dawson 17 | R. Wilson 6 | D. Patton 11 |
| December 6, 2027 | DELAWARE FIGHTIN' BLUE HENS | L 56-60 | 5-3 | D. Patton 14 | R. Wilson 4 | E. Kresse 12 |
| December 13, 2027 | MOREHEAD STATE EAGLES | L 51-64 | 5-4 | D. Patton 10 | L. Dawson 5 | D. Patton 10 |
| December 20, 2027 | @ Texas Christian Horned Frogs (4-3, 4-1 Home) | - | | | | |
| December 26, 2027 | @ NC-State Wolfpack (5-2, 0-0, 5-2 Home)* | - | | | | |
| December 28, 2027 | @ Syracuse Orange (3-5, 0-0, 3-4 Home)* | - | | | | |
| January 2, 2028 | PITTSBURGH PANTHERS (9-2, 0-0, 0-1 Away)* | - | | | | |
| January 4, 2028 | @ Louisville Cardinals (8-1, 0-0, 5-1 Home)* | - | | | | |
| January 9, 2028 | @ Clemson Tigers (7-2, 0-0, 7-2 Home)* | - | | | | |
| January 11, 2028 | GEORGIA TECH YELLOW JACKETS (8-1, 0-0, 1-1 Away)* | - | | | | |
| January 16, 2028 | @ California Golden Bears (5-3, 0-0, 4-2 Home)* | - | | | | |
| January 18, 2028 | @ Duke Blue Devils (6-4, 0-0, 4-1 Home)* | - | | | | |
| January 23, 2028 | @ Boston College Eagles (5-4, 0-0, 4-1 Home)* | - | | | | |
| January 25, 2028 | @ Southern Methodist Mustangs (4-4, 0-0, 3-3 Home)* | - | | | | |
| January 30, 2028 | FLORIDA STATE SEMINOLES (7-3, 0-0, 0-0 Away)* | - | | | | |
| February 1, 2028 | VIRGINIA CAVALIERS (9-1, 0-0, 2-1 Away)* | - | | | | |
| February 6, 2028 | VIRGINIA TECH HOKIES (5-3, 0-0, 0-1 Away)* | - | | | | |
| February 8, 2028 | @ Miami (FL) Hurricanes (5-2, 0-0, 5-0 Home)* | - | | | | |
| February 13, 2028 | NORTH CAROLINA TAR HEELS (9-1, 0-0, 0-0 Away)* | - | | | | |
| February 15, 2028 | STANFORD CARDINAL (6-2, 0-0, 0-1 Away)* | - | | | | |
| February 20, 2028 | @ Wake Forest Demon Deacons (6-2, 0-0, 6-0 Home)* | - | | | | |
| February 22, 2028 | NC-STATE WOLFPACK (5-2, 0-0, 0-0 Away)* | - | | | | |
| February 27, 2028 | SOUTHERN METHODIST MUSTANGS (4-4, 0-0, 0-0 Away)* | - | | | | |
| March 1, 2028 | DUKE BLUE DEVILS (6-4, 0-0, 0-2 Away)* | - | | | | |
