| November 16, 2027 | BUCKNELL BISON | W 60-45 | 1-0 | D. Allen 16 | P. Harrell 6 | D. Allen 13 |
| November 19, 2027 | ELON PHOENIX | W 86-66 | 2-0 | T. Grace 22 | D. Redd 6 | P. Harrell 6 |
| November 23, 2027 | HAMPTON PIRATES | W 90-57 | 3-0 | T. Grace 20 | D. Redd 8 | M. Mociler 6 |
| November 26, 2027 | @ #15 Iowa State Cyclones | L 64-76 | 3-1 | T. Grace 20 | D. Redd 6 | T. Grace 9 |
| November 30, 2027 | WESTERN KENTUCKY HILLTOPPERS | W 72-65 | 4-1 | T. Grace 19 | P. Harrell 4 | P. Harrell 7 |
| December 7, 2027 | ILLINOIS-CHICAGO FLAMES | W 60-40 | 5-1 | D. Allen 12 | S. Adams 5 | T. Thompson 8 |
| December 9, 2027 | DREXEL DRAGONS Cayman Islands Classic | W 65-51 | 6-1 | D. Allen 15 | D. Redd 5 | D. Allen 9 |
| December 10, 2027 | TULSA GOLDEN HURRICANES Cayman Islands Classic | L 64-68 | 6-2 | M. Mociler 15 | P. Harrell 3 | T. Grace 9 |
| December 14, 2027 | SACRAMENTO STATE HORNETS | W 70-57 | 7-2 | T. Grace 13 | D. Redd 4 | D. Allen 9 |
| December 21, 2027 | LONG BEACH STATE SHARKS | W 83-65 | 8-2 | T. Grace 29 | M. Mociler 7 | D. Allen 7 |
| December 26, 2027 | @ Miami (FL) Hurricanes* | L 58-74 | 8-3 | P. Harrell 9 | D. Redd 7 | P. Harrell 11 |
| December 28, 2027 | @ Boston College Eagles* | W 73-67 | 9-3 | P. Harrell 24 | D. Redd 5 | D. Allen 6 |
| January 2, 2028 | #12 VIRGINIA CAVALIERS* | L 67-94 | 9-4 | T. Grace 22 | D. Redd 3 | P. Harrell 8 |
| January 4, 2028 | @ #9 Louisville Cardinals* | L 66-77 | 9-5 | D. Allen 16 | D. Redd 4 | D. Allen 8 |
| January 9, 2028 | WAKE FOREST DEMON DEACONS* | W 90-80 OT | 10-5 | D. Redd 17 | P. Harrell 5 | P. Harrell 12 |
| January 11, 2028 | CALIFORNIA GOLDEN BEARS* | W 74-64 | 11-5 | M. Mociler 16 | P. Harrell 3 | D. Allen 7 |
| January 16, 2028 | STANFORD CARDINAL* | W 71-53 | 12-5 | D. Redd 23 | T. Grace 7 | P. Harrell 11 |
| January 18, 2028 | PITTSBURGH PANTHERS* | W 78-75 | 13-5 | D. Redd 15 | D. Redd 5 | M. DeClercq 9 |
| January 23, 2028 | @ Virginia Tech Hokies* | W 67-64 | 14-5 | P. Harrell 24 | D. Redd 9 | D. Allen 8 |
| January 25, 2028 | @ Notre Dame Fighting Irish* | L 48-58 | 14-6 | D. Allen 15 | D. Redd 2 | D. Allen 8 |
| January 30, 2028 | GEORGIA TECH YELLOW JACKETS* | W 75-58 | 15-6 | D. Allen 17 | M. Mociler 6 | P. Harrell 8 |
| February 1, 2028 | @ Clemson Tigers* | L 55-70 | 15-7 | T. Grace 10 | D. Redd 3 | T. Grace 6 |
| February 6, 2028 | @ North Carolina Tar Heels* | L 59-72 | 15-8 | M. Mociler 15 | T. Grace 3 | P. Harrell 11 |
| February 8, 2028 | @ #17 Syracuse Orange* | L 63-82 | 15-9 | P. Harrell 17 | M. Garcia 4 | P. Harrell 7 |
| February 13, 2028 | @ Southern Methodist Mustangs* | L 61-73 | 15-10 | T. Grace 21 | D. Redd 7 | P. Harrell 12 |
| February 15, 2028 | #1 DUKE BLUE DEVILS* | L 47-62 | 15-11 | D. Allen 9 | D. Redd 6 | P. Harrell 13 |
| February 20, 2028 | FLORIDA STATE SEMINOLES* | W 76-56 | 16-11 | D. Redd 12 | M. Mociler 4 | P. Harrell 8 |
| February 22, 2028 | #8 LOUISVILLE CARDINALS* | L 51-76 | 16-12 | T. Grace 14 | D. Redd 3 | T. Grace 6 |
| February 27, 2028 | SOUTHERN METHODIST MUSTANGS* | W 79-71 | 17-12 | M. Mociler 26 | D. Redd 5 | P. Harrell 7 |
| March 1, 2028 | @ #1 Duke Blue Devils* | L 59-70 | 17-13 | M. Mociler 12 | D. Redd 5 | P. Harrell 10 |
| March 8, 2028 | STANFORD CARDINAL (10-20, 2-8 Away) ACC Tournament | - | | | | |
