| November 13, 2027 | BELLARMINE KNIGHTS | W 91-78 | 1-0 | A. Shields 24 | J. Block 4 | L. Wesley 7 |
| November 16, 2027 | @ New Orleans Privateers | L 69-84 | 1-1 | J. Block 18 | A. Shields 4 | A. Nunn 7 |
| November 19, 2027 | NIAGARA PURPLE EAGLES | L 58-73 | 1-2 | R. Rozier 11 | A. Shields 7 | L. Gainous 9 |
| November 23, 2027 | @ Auburn Tigers | L 67-90 | 1-3 | J. Block 21 | A. Shields 10 | L. Wesley 5 |
| November 24, 2027 | CENTRAL MICHIGAN CHIPPEWAS | L 55-78 | 1-4 | J. Block 12 | J. Block 3 | J. Block 4 |
| November 29, 2027 | @ James Madison Dukes | W 65-59 | 2-4 | A. Shields 15 | A. Shields 2 | H. Lyles 8 |
| December 3, 2027 | COLGATE RAIDERS | L 85-89 | 2-5 | L. Wesley 17 | R. Rozier 6 | J. Block 6 |
| December 6, 2027 | SOUTH DAKOTA COYOTES | L 66-85 | 2-6 | A. Shields 14 | A. Shields 5 | L. Wesley 6 |
| December 10, 2027 | @ Little Rock Trojans | L 74-88 | 2-7 | L. Gainous 12 | L. Patton 3 | R. Rozier 8 |
| December 14, 2027 | @ Texas Tech Red Raiders | L 55-66 | 2-8 | H. Lyles 11 | A. Shields 4 | L. Wesley 8 |
| December 17, 2027 | SE LOUISIANA LIONS | W 93-85 | 3-8 | J. Block 19 | J. Block 8 | H. Lyles 10 |
| December 21, 2027 | @ Santa Clara Broncos (5-4, 4-0 Home) | - | | | | |
| December 24, 2027 | @ Missouri Tigers (8-2, 7-0 Home) | - | | | | |
| December 27, 2027 | SOUTH DAKOTA STATE JACKRABBITS (2-7, 0-4 Away) | - | | | | |
| December 31, 2027 | CALIFORNIA BAPTIST LANCERS (4-5, 1-3 Away) | - | | | | |
| January 11, 2028 | @ Morgan State Bears (6-5, 0-0, 3-2 Home)* | - | | | | |
| January 14, 2028 | NORFOLK STATE SPARTANS (8-3, 0-0, 6-2 Away)* | - | | | | |
| January 18, 2028 | @ Howard Bison (5-6, 0-0, 2-1 Home)* | - | | | | |
| January 21, 2028 | SOUTH CAROLINA STATE BULLDOGS (2-9, 0-0, 1-6 Away)* | - | | | | |
| January 25, 2028 | @ MD-Eastern Shore Hawks (2-9, 0-0, 2-2 Home)* | - | | | | |
| January 28, 2028 | COPPIN STATE EAGLES (3-8, 0-0, 1-8 Away)* | - | | | | |
| February 1, 2028 | @ Delaware State Hornets (9-2, 0-0, 4-1 Home)* | - | | | | |
| February 4, 2028 | MORGAN STATE BEARS (6-5, 0-0, 3-3 Away)* | - | | | | |
| February 8, 2028 | @ Norfolk State Spartans (8-3, 0-0, 2-1 Home)* | - | | | | |
| February 11, 2028 | HOWARD BISON (5-6, 0-0, 3-5 Away)* | - | | | | |
| February 15, 2028 | @ South Carolina State Bulldogs (2-9, 0-0, 1-3 Home)* | - | | | | |
| February 18, 2028 | MD-EASTERN SHORE HAWKS (2-9, 0-0, 0-7 Away)* | - | | | | |
| February 22, 2028 | @ Coppin State Eagles (3-8, 0-0, 2-0 Home)* | - | | | | |
| February 25, 2028 | DELAWARE STATE HORNETS (9-2, 0-0, 5-1 Away)* | - | | | | |
