| November 14, 2027 | @ Massachusetts Minutemen | L 95-103 | 0-1 | M. Chapman 19 | K. Seymour 5 | M. Chapman 11 |
| November 23, 2027 | IDAHO VANDALS | W 75-71 | 1-1 | R. Dennis 16 | K. Seymour 4 | M. Chapman 10 |
| November 24, 2027 | NJIT HIGHLANDERS | L 69-72 | 1-2 | M. Chapman 21 | K. Seymour 4 | M. Chapman 12 |
| November 29, 2027 | @ #11 Pittsburgh Panthers | L 61-90 | 1-3 | L. Hunter 11 | L. Hunter 5 | M. Chapman 10 |
| December 7, 2027 | @ #21 Oklahoma State Cowboys | L 44-75 | 1-4 | M. Chapman 14 | L. Hunter 6 | M. Chapman 9 |
| December 9, 2027 | @ UC-Irvine Anteaters Nassau Championship | W 73-66 | 2-4 | J. Frazier 16 | L. Hunter 3 | M. Chapman 9 |
| December 10, 2027 | @ Northeastern Huskies Nassau Championship | L 75-87 | 2-5 | L. Hunter 17 | K. Seymour 4 | J. Frazier 7 |
| December 12, 2027 | @ UC-Davis Aggies | W 78-70 | 3-5 | K. Seymour 17 | M. Chapman 5 | J. Frazier 8 |
| December 16, 2027 | @ Marshall Thundering Herd | L 72-83 | 3-6 | K. Seymour 15 | L. Hunter 3 | J. Frazier 7 |
| December 21, 2027 | @ #1 Kansas Jayhawks | L 58-74 | 3-7 | L. Hunter 16 | A. Braxton 4 | J. Frazier 6 |
| December 26, 2027 | @ Drake Bulldogs* | L 61-76 | 3-8 | L. Hunter 14 | A. Braxton 4 | K. Cleaver 8 |
| December 29, 2027 | @ Southern Illinois Salukis* | L 64-77 | 3-9 | L. Hunter 18 | L. Hunter 3 | J. Frazier 8 |
| January 2, 2028 | @ Indiana State Sycamores* | L 58-70 | 3-10 | L. Hunter 14 | K. Cleaver 3 | M. Chapman 9 |
| January 5, 2028 | @ Illinois-Chicago Flames* | W 87-78 | 4-10 | M. Chapman 24 | L. Hunter 6 | M. Chapman 15 |
| January 9, 2028 | NORTHERN IOWA PANTHERS* | W 106-98 | 5-10 | L. Hunter 19 | L. Hunter 5 | J. Frazier 6 |
| January 12, 2028 | BRADLEY BRAVES* | W 78-70 | 6-10 | L. Hunter 23 | L. Hunter 4 | J. Frazier 9 |
| January 16, 2028 | VALPARAISO BEACONS* | L 72-78 | 6-11 | M. Chapman 19 | A. Braxton 4 | M. Chapman 17 |
| January 19, 2028 | @ Murray State Racers* | L 81-96 | 6-12 | M. Chapman 18 | M. Chapman 3 | M. Chapman 8 |
| January 23, 2028 | @ Illinois State Redbirds* | L 71-81 | 6-13 | L. Hunter 14 | L. Hunter 3 | K. Cleaver 7 |
| January 26, 2028 | @ Evansville Purple Aces* | L 87-92 | 6-14 | M. Chapman 18 | L. Hunter 3 | M. Chapman 6 |
| January 30, 2028 | MURRAY STATE RACERS* | L 89-92 | 6-15 | R. Dennis 19 | L. Hunter 5 | M. Chapman 11 |
| February 2, 2028 | ILLINOIS STATE REDBIRDS* | W 90-78 | 7-15 | L. Hunter 19 | L. Hunter 3 | M. Chapman 6 |
| February 6, 2028 | @ Bradley Braves* | L 65-77 | 7-16 | J. Frazier 14 | L. Hunter 7 | M. Chapman 9 |
| February 9, 2028 | @ Valparaiso Beacons* | L 68-86 | 7-17 | M. Chapman 13 | L. Hunter 4 | M. Chapman 7 |
| February 13, 2028 | INDIANA STATE SYCAMORES* | W 89-77 | 8-17 | M. Chapman 20 | R. Dennis 5 | M. Chapman 11 |
| February 16, 2028 | ILLINOIS-CHICAGO FLAMES* | W 76-68 | 9-17 | M. Chapman 13 | L. Hunter 5 | M. Chapman 11 |
| February 20, 2028 | DRAKE BULLDOGS* | W 78-74 | 10-17 | J. Frazier 16 | A. Braxton 4 | M. Chapman 10 |
| February 23, 2028 | EVANSVILLE PURPLE ACES* | L 92-95 OT | 10-18 | L. Hunter 25 | K. Cleaver 3 | M. Chapman 12 |
| February 27, 2028 | SOUTHERN ILLINOIS SALUKIS* | L 71-75 | 10-19 | M. Chapman 18 | K. Seymour 6 | M. Chapman 9 |
| March 2, 2028 | @ Belmont Bruins* | L 76-99 | 10-20 | R. Dennis 13 | L. Hunter 4 | M. Chapman 11 |
| March 7, 2028 | @ Illinois State Redbirds MVC Tournament | W 86-75 | 11-20 | L. Hunter 33 | L. Hunter 5 | M. Chapman 10 |
| March 8, 2028 | @ Northern Iowa Panthers MVC Tournament | L 63-79 | 11-21 | K. Seymour 14 | L. Hunter 4 | M. Chapman 10 |
