| November 16, 2027 | AUSTIN PEAY GOVERNORS | W 75-51 | 1-0 | C. Roberts 20 | J. Lampley 7 | J. Arnold 8 |
| November 18, 2027 | @ Indiana Hoosiers Sunshine Slam | W 83-68 | 2-0 | J. Lampley 22 | C. Cleaver 6 | J. Tillete 8 |
| November 19, 2027 | @ #17 Butler Bulldogs Sunshine Slam | L 63-67 | 2-1 | C. Cleaver 11 | C. Cleaver 4 | C. Cleaver 9 |
| November 21, 2027 | SOUTHERN UTAH THUNDERBIRDS | W 58-50 | 3-1 | J. Tillete 12 | J. Lampley 7 | J. Arnold 8 |
| November 24, 2027 | NORTHERN KENTUCKY NORSE | W 76-64 | 4-1 | D. Trombley 21 | D. Trombley 5 | J. Tillete 16 |
| December 2, 2027 | @ Nevada-Las Vegas Runnin' Rebels | W 54-43 | 5-1 | C. Roberts 20 | J. Lampley 3 | C. Cleaver 11 |
| December 7, 2027 | QUINNIPIAC BOBCATS | L 57-65 | 5-2 | D. Trombley 19 | J. Lampley 3 | J. Arnold 8 |
| December 10, 2027 | NORTH FLORIDA OSPREY | W 96-75 | 6-2 | J. Tillete 28 | J. Lampley 8 | C. Cleaver 10 |
| December 12, 2027 | CHICAGO STATE COUGARS | W 74-59 | 7-2 | D. Trombley 24 | J. Arnold 3 | J. Tillete 15 |
| December 17, 2027 | @ Arizona State Sun Devils | L 81-96 | 7-3 | C. Roberts 17 | J. Lampley 6 | C. Roberts 7 |
| December 21, 2027 | SAINT PETERS PEACOCKS | W 66-51 | 8-3 | J. Tillete 17 | J. Lampley 6 | J. Tillete 13 |
| December 22, 2027 | SAN DIEGO TOREROS | W 80-76 | 9-3 | J. Tillete 20 | J. Lampley 5 | J. Tillete 9 |
| December 29, 2027 | @ #17 Tennessee Volunteers* | L 61-81 | 9-4 | C. Cleaver 10 | J. Lampley 3 | J. Tillete 10 |
| January 2, 2028 | GEORGIA BULLDOGS* | L 65-82 | 9-5 | D. Trombley 19 | J. Lampley 6 | C. Cleaver 8 |
| January 5, 2028 | @ Auburn Tigers* | L 79-80 | 9-6 | W. Warren 19 | J. Lampley 5 | J. Tillete 11 |
| January 9, 2028 | SOUTH CAROLINA GAMECOCKS* | L 59-64 | 9-7 | J. Tillete 16 | D. Trombley 3 | C. Cleaver 8 |
| January 12, 2028 | LOUISIANA STATE FIGHTING TIGERS* | W 88-68 | 10-7 | J. Tillete 23 | J. Lampley 9 | C. Roberts 9 |
| January 16, 2028 | @ Kentucky Wildcats* | L 70-90 | 10-8 | D. Trombley 18 | J. Lampley 9 | D. Trombley 6 |
| January 19, 2028 | MISSISSIPPI STATE BULLDOGS* | W 69-63 | 11-8 | J. Tillete 19 | D. Trombley 5 | C. Cleaver 6 |
| January 26, 2028 | @ Georgia Bulldogs* | W 65-58 | 12-8 | J. Tillete 15 | J. Lampley 7 | C. Cleaver 7 |
| January 30, 2028 | VANDERBILT COMMODORES* | W 75-62 | 13-8 | C. Roberts 19 | J. Tillete 4 | C. Cleaver 12 |
| February 2, 2028 | @ Texas Longhorns* | L 59-79 | 13-9 | D. Trombley 17 | J. Lampley 5 | J. Tillete 4 |
| February 6, 2028 | @ Texas A&M Aggies* | L 62-83 | 13-10 | J. Tillete 13 | J. Lampley 5 | C. Cleaver 8 |
| February 9, 2028 | KENTUCKY WILDCATS* | L 62-70 | 13-11 | J. Tillete 15 | J. Tillete 5 | J. Arnold 6 |
| February 13, 2028 | ARKANSAS RAZORBACKS* | W 77-73 | 14-11 | J. Tillete 16 | W. Warren 4 | C. Cleaver 7 |
| February 16, 2028 | @ Missouri Tigers* | W 83-77 | 15-11 | C. Roberts 16 | C. Cleaver 4 | C. Cleaver 7 |
| February 20, 2028 | @ Mississippi State Bulldogs* | W 89-79 | 16-11 | D. Trombley 26 | C. Cleaver 5 | J. Tillete 8 |
| February 23, 2028 | OKLAHOMA SOONERS* | L 67-78 | 16-12 | J. Arnold 15 | D. Trombley 6 | J. Arnold 5 |
| February 27, 2028 | @ #4 Florida Gators* | L 61-76 | 16-13 | D. Trombley 15 | J. Lampley 6 | C. Cleaver 7 |
| March 2, 2028 | ALABAMA CRIMSON TIDE* | W 83-66 | 17-13 | C. Cleaver 24 | D. Trombley 4 | C. Cleaver 6 |
| March 8, 2028 | ARKANSAS RAZORBACKS SEC Tournament | W 88-80 | 18-13 | D. Trombley 31 | J. Lampley 4 | J. Arnold 7 |
| March 9, 2028 | @ Mississippi State Bulldogs SEC Tournament | W 76-63 | 19-13 | J. Tillete 14 | C. Cleaver 6 | J. Arnold 11 |
| March 10, 2028 | @ #4 Florida Gators SEC Tournament | L 60-71 | 19-14 | J. Tillete 18 | J. Lampley 3 | J. Arnold 8 |
