| November 16, 2027 | NORTH CAROLINA A&T AGGIES | W 89-71 | 1-0 | D. Bailey 21 | D. Bailey 7 | M. Tony-El 7 |
| November 17, 2027 | MONTANA STATE BOBCATS | W 98-91 OT | 2-0 | M. Rosen 26 | D. Bailey 4 | M. Nichols 10 |
| November 23, 2027 | OMAHA MAVERICKS | L 73-82 | 2-1 | M. Rosen 14 | D. Bailey 9 | C. Surpin 8 |
| November 25, 2027 | LAMAR CARDINALS | L 72-75 | 2-2 | D. Bailey 17 | M. Tony-El 5 | C. Surpin 9 |
| November 28, 2027 | EASTERN KENTUCKY COLONELS | W 101-87 | 3-2 | M. Rosen 20 | D. Bailey 7 | C. Surpin 8 |
| December 2, 2027 | INCARNATE WORD CARDINALS | L 75-84 | 3-3 | M. Nichols 20 | M. Rosen 7 | M. Tony-El 9 |
| December 6, 2027 | TEXAS SOUTHERN TIGERS | W 81-76 | 4-3 | M. Rosen 20 | D. Bailey 5 | M. Nichols 8 |
| December 9, 2027 | MERCYHURST LAKERS | W 89-79 | 5-3 | D. Bailey 29 | D. Bailey 6 | M. Tony-El 10 |
| December 13, 2027 | LOYOLA MARYMOUNT LIONS | L 69-72 | 5-4 | M. Nichols 14 | D. Marquardt 6 | M. Nichols 9 |
| December 16, 2027 | KANSAS CITY KANGAROOS | W 101-91 | 6-4 | M. Rosen 32 | D. Bailey 3 | M. Nichols 7 |
| December 21, 2027 | JAMES MADISON DUKES | W 83-75 | 7-4 | D. Bailey 17 | D. Bailey 3 | C. Surpin 8 |
| December 30, 2027 | SOUTH CAROLINA GAMECOCKS* | L 87-89 | 7-5 | D. Bailey 20 | C. Surpin 4 | C. Surpin 7 |
| January 3, 2028 | @ Arkansas Razorbacks* | L 96-108 | 7-6 | D. Bailey 23 | D. Bailey 4 | C. Surpin 8 |
| January 6, 2028 | @ Louisiana State Fighting Tigers* | W 90-81 | 8-6 | M. Rosen 23 | D. Bailey 5 | C. Surpin 7 |
| January 10, 2028 | MISSISSIPPI STATE BULLDOGS* | L 70-80 | 8-7 | D. Bailey 14 | D. Bailey 4 | M. Tony-El 9 |
| January 13, 2028 | @ Georgia Bulldogs* | L 80-93 | 8-8 | D. Bailey 19 | D. Bailey 6 | M. Tony-El 6 |
| January 20, 2028 | @ #16 Vanderbilt Commodores* | L 70-92 | 8-9 | D. Bailey 21 | D. Bailey 3 | B. Eason 4 |
| January 24, 2028 | OKLAHOMA SOONERS* | L 77-86 | 8-10 | D. Bailey 14 | D. Bailey 7 | M. Nichols 11 |
| January 27, 2028 | #22 ALABAMA CRIMSON TIDE* | L 69-97 | 8-11 | D. Bailey 11 | D. Bailey 5 | M. Tony-El 7 |
| January 31, 2028 | @ Missouri Tigers* | L 70-95 | 8-12 | B. Eason 14 | D. Bailey 4 | D. Bailey 6 |
| February 3, 2028 | LOUISIANA STATE FIGHTING TIGERS* | L 80-92 | 8-13 | M. Rosen 26 | D. Bailey 7 | M. Nichols 8 |
| February 7, 2028 | @ Mississippi State Bulldogs* | L 81-90 | 8-14 | M. Rosen 18 | M. Nichols 5 | M. Tony-El 6 |
| February 10, 2028 | @ #19 Texas A&M Aggies* | L 63-67 | 8-15 | M. Rosen 18 | D. Bailey 7 | J. Durham 8 |
| February 14, 2028 | TEXAS LONGHORNS* | L 61-78 | 8-16 | M. Rosen 19 | D. Bailey 10 | M. Nichols 9 |
| February 17, 2028 | AUBURN TIGERS* | L 74-83 | 8-17 | M. Nichols 16 | M. Rosen 5 | C. Surpin 7 |
| February 21, 2028 | #19 KENTUCKY WILDCATS* | L 67-91 | 8-18 | M. Rosen 12 | D. Bailey 4 | M. Nichols 7 |
| February 24, 2028 | @ Tennessee Volunteers* | L 77-78 | 8-19 | D. Bailey 16 | D. Bailey 5 | C. Surpin 6 |
| February 28, 2028 | @ #7 Florida Gators* | L 72-106 | 8-20 | D. Bailey 16 | D. Bailey 5 | C. Surpin 6 |
| March 3, 2028 | GEORGIA BULLDOGS* | L 71-92 | 8-21 | D. Bailey 14 | D. Bailey 4 | J. Durham 7 |
| March 8, 2028 | @ Tennessee Volunteers (19-11, 15-4 Home) SEC Tournament | - | | | | |
