| November 15, 2027 | NEW HAMPSHIRE WILDCATS | W 78-40 | 1-0 | M. Sylla 18 | M. Sylla 4 | M. Sylla 11 |
| November 19, 2027 | INCARNATE WORD CARDINALS | W 74-58 | 2-0 | E. Branch 23 | D. Lewis 5 | E. Branch 13 |
| November 21, 2027 | KENNESAW STATE OWLS | W 80-60 | 3-0 | E. Branch 18 | T. Turner 4 | E. Branch 11 |
| November 25, 2027 | MILWAUKEE PANTHERS Paradise Jam | L 59-86 | 3-1 | D. Lewis 12 | M. Fletcher 3 | M. Sylla 8 |
| November 29, 2027 | RHODE ISLAND RAMS | W 72-62 | 4-1 | T. Galloway 17 | D. Lewis 6 | E. Branch 5 |
| December 3, 2027 | #20 NOTRE DAME FIGHTING IRISH | W 78-69 | 5-1 | E. Branch 26 | T. Galloway 6 | E. Branch 7 |
| December 7, 2027 | @ North Carolina Tar Heels | L 88-93 | 5-2 | E. Branch 23 | D. Lewis 5 | M. Sylla 10 |
| December 13, 2027 | BINGHAMTON BEARCATS | W 76-59 | 6-2 | T. Galloway 13 | M. Sylla 4 | M. Sylla 9 |
| December 21, 2027 | #19 CLEMSON TIGERS | W 80-61 | 7-2 | M. Sylla 16 | D. Lewis 5 | M. Sylla 15 |
| December 26, 2027 | @ Ohio State Buckeyes* | L 77-78 | 7-3 | T. Turner 16 | T. Galloway 8 | M. Sylla 8 |
| December 28, 2027 | @ Washington Huskies* | L 73-89 | 7-4 | E. Branch 22 | M. Tyler 5 | E. Branch 10 |
| January 2, 2028 | RUTGERS SCARLET KNIGHTS* | W 73-68 | 8-4 | E. Branch 14 | M. Tyler 3 | E. Branch 11 |
| January 4, 2028 | @ Southern California Trojans* | W 109-102 | 9-4 | E. Branch 28 | D. Lewis 10 | M. Sylla 10 |
| January 9, 2028 | @ Northwestern Wildcats* | L 70-75 | 9-5 | T. Turner 14 | M. Tyler 4 | T. Turner 7 |
| January 11, 2028 | #6 WISCONSIN BADGERS* | L 71-87 | 9-6 | E. Branch 17 | D. Lewis 3 | M. Sylla 6 |
| January 16, 2028 | @ Illinois Fighting Illini* | L 86-99 | 9-7 | E. Branch 26 | T. Galloway 8 | M. Sylla 7 |
| January 18, 2028 | @ #24 Michigan Wolverines* | L 74-90 | 9-8 | M. Sylla 18 | D. Lewis 7 | M. Sylla 12 |
| January 23, 2028 | @ Penn State Nittany Lions* | W 84-73 | 10-8 | D. Lewis 16 | M. Tyler 5 | M. Sylla 11 |
| January 25, 2028 | @ Iowa Hawkeyes* | L 65-76 | 10-9 | M. Sylla 14 | D. Lewis 7 | M. Sylla 10 |
| January 30, 2028 | #15 PURDUE BOILERMAKERS* | L 68-75 | 10-10 | D. Lewis 18 | M. Sylla 3 | M. Sylla 14 |
| February 1, 2028 | INDIANA HOOSIERS* | W 76-68 | 11-10 | D. Lewis 18 | T. Galloway 3 | M. Tyler 6 |
| February 6, 2028 | NEBRASKA CORNHUSKERS* | L 73-76 | 11-11 | E. Branch 20 | M. Fletcher 7 | M. Sylla 8 |
| February 8, 2028 | @ Maryland Terrapins* | L 80-90 | 11-12 | T. Galloway 19 | T. Turner 3 | M. Sylla 10 |
| February 13, 2028 | UCLA BRUINS* | W 73-67 | 12-12 | E. Branch 23 | D. Lewis 5 | M. Sylla 9 |
| February 15, 2028 | #21 OREGON DUCKS* | W 78-77 | 13-12 | D. Lewis 19 | M. Tyler 7 | E. Branch 11 |
| February 20, 2028 | @ #4 Michigan State Spartans* | L 85-98 | 13-13 | D. Lewis 26 | D. Lewis 5 | E. Branch 5 |
| February 22, 2028 | OHIO STATE BUCKEYES* | W 92-74 | 14-13 | E. Branch 24 | T. Galloway 4 | T. Turner 9 |
| February 27, 2028 | IOWA HAWKEYES* | W 74-60 | 15-13 | M. Sylla 14 | D. Lewis 4 | M. Sylla 16 |
| March 1, 2028 | MICHIGAN WOLVERINES* | W 90-80 | 16-13 | D. Lewis 33 | T. Turner 5 | M. Sylla 13 |
| March 8, 2028 | SOUTHERN CALIFORNIA TROJANS (14-15, 4-7 Away) Big 10 Tournament | - | | | | |
