| November 16, 2027 | TOLEDO ROCKETS | W 90-69 | 1-0 | O. Onley 24 | O. Onley 7 | C. Thomas 9 |
| November 23, 2027 | MCNEESE STATE COWBOYS | W 88-80 | 2-0 | J. Burns 22 | O. Onley 6 | C. Thomas 12 |
| November 26, 2027 | @ Georgia Bulldogs | L 73-81 | 2-1 | J. Burns 15 | O. Onley 6 | M. Hart 7 |
| November 30, 2027 | IONA GAELS | W 91-71 | 3-1 | C. Thomas 21 | J. Burns 6 | C. Thomas 10 |
| December 3, 2027 | HAWAII RAINBOW WARRIORS | W 79-76 | 4-1 | J. Burns 20 | O. Onley 3 | M. Hart 6 |
| December 6, 2027 | DUQUESNE DUKES | L 82-83 | 4-2 | J. Burns 30 | O. Onley 6 | T. Marquis 11 |
| December 9, 2027 | SAN JOSE STATE SPARTANS Nassau Championship | W 90-78 | 5-2 | J. Burns 27 | O. Onley 8 | C. Thomas 12 |
| December 10, 2027 | HOFSTRA PRIDE Nassau Championship | W 86-75 | 6-2 | J. Burns 15 | C. Blanks 4 | C. Thomas 9 |
| December 11, 2027 | MIAMI (FL) HURRICANES Nassau Championship | W 81-65 | 7-2 | J. Burns 31 | O. Onley 5 | C. Thomas 9 |
| December 14, 2027 | @ Arkansas Razorbacks | L 75-89 | 7-3 | J. Burns 18 | T. Marquis 3 | C. Thomas 10 |
| December 21, 2027 | MIAMI (OH) REDHAWKS | W 94-69 | 8-3 | J. Burns 38 | O. Onley 6 | C. Thomas 11 |
| December 26, 2027 | RUTGERS SCARLET KNIGHTS* | W 93-68 | 9-3 | J. Burns 25 | O. Onley 5 | C. Thomas 11 |
| December 28, 2027 | @ Ohio State Buckeyes* | W 99-90 | 10-3 | J. Burns 29 | M. Hart 4 | C. Thomas 9 |
| January 2, 2028 | @ Washington Huskies* | W 83-68 | 11-3 | J. Burns 23 | O. Onley 7 | M. Hart 12 |
| January 4, 2028 | #7 WISCONSIN BADGERS* | L 92-108 | 11-4 | J. Burns 48 | O. Onley 7 | C. Thomas 8 |
| January 9, 2028 | @ #2 Michigan State Spartans* | L 95-99 | 11-5 | J. Burns 22 | O. Onley 8 | C. Thomas 13 |
| January 11, 2028 | #14 OREGON DUCKS* | L 81-85 | 11-6 | J. Burns 28 | O. Onley 3 | C. Thomas 18 |
| January 16, 2028 | @ Nebraska Cornhuskers* | L 86-101 | 11-7 | J. Burns 30 | O. Onley 6 | C. Thomas 11 |
| January 18, 2028 | MINNESOTA GOLDEN GOPHERS* | W 90-74 | 12-7 | J. Burns 36 | O. Onley 5 | C. Thomas 9 |
| January 23, 2028 | @ Northwestern Wildcats* | W 89-85 | 13-7 | J. Burns 30 | O. Onley 5 | C. Thomas 9 |
| January 25, 2028 | @ Penn State Nittany Lions* | L 65-76 | 13-8 | J. Burns 14 | T. Marquis 4 | C. Thomas 13 |
| January 30, 2028 | #24 IOWA HAWKEYES* | W 92-76 | 14-8 | J. Burns 38 | O. Onley 5 | C. Thomas 12 |
| February 1, 2028 | @ Maryland Terrapins* | W 74-58 | 15-8 | J. Burns 19 | C. Blanks 5 | J. Burns 9 |
| February 6, 2028 | INDIANA HOOSIERS* | W 81-79 | 16-8 | J. Burns 23 | C. Blanks 4 | C. Thomas 11 |
| February 8, 2028 | #14 PURDUE BOILERMAKERS* | L 76-81 OT | 16-9 | J. Burns 29 | J. Burns 6 | C. Thomas 11 |
| February 13, 2028 | @ Illinois Fighting Illini* | W 84-83 | 17-9 | C. Thomas 25 | C. Blanks 8 | C. Blanks 11 |
| February 15, 2028 | @ Southern California Trojans* | L 89-92 | 17-10 | O. Onley 24 | C. Blanks 6 | C. Thomas 12 |
| February 20, 2028 | UCLA BRUINS* | W 102-80 | 18-10 | O. Onley 29 | C. Blanks 9 | C. Thomas 8 |
| February 22, 2028 | NEBRASKA CORNHUSKERS* | L 66-75 | 18-11 | J. Burns 18 | C. Blanks 7 | C. Thomas 13 |
| February 27, 2028 | OHIO STATE BUCKEYES* | L 57-76 | 18-12 | J. Burns 13 | O. Onley 3 | C. Thomas 8 |
| March 1, 2028 | @ Minnesota Golden Gophers* | L 80-90 | 18-13 | J. Burns 36 | C. Blanks 3 | C. Thomas 14 |
| March 9, 2028 | TBD Big 10 Tournament | - | | | | |
