| November 15, 2027 | @ Arkansas Razorbacks | W 72-61 | 1-0 | E. Beck 24 | C. Hurd 5 | I. Ekpeyong 7 |
| November 18, 2027 | @ Texas Tech Red Raiders | L 69-87 | 1-1 | E. Beck 19 | C. McCarthy 6 | I. Ekpeyong 9 |
| November 22, 2027 | #13 BUTLER BULLDOGS | W 68-61 | 2-1 | C. McCarthy 19 | C. McCarthy 5 | C. Hurd 6 |
| November 29, 2027 | SOUTH CAROLINA GAMECOCKS | W 74-44 | 3-1 | C. McCarthy 13 | C. Hurd 6 | C. Hurd 10 |
| December 6, 2027 | UC-SANTA BARBARA GAUCHOS | W 90-69 | 4-1 | E. Beck 23 | E. Beck 5 | I. Ekpeyong 7 |
| December 9, 2027 | COLORADO STATE RAMS | W 60-54 | 5-1 | C. Hurd 15 | E. Beck 5 | D. Rozier 9 |
| December 13, 2027 | SAN DIEGO STATE AZTECS | W 77-76 OT | 6-1 | D. Rozier 22 | E. Beck 5 | D. Rozier 14 |
| December 20, 2027 | ARIZONA STATE SUN DEVILS (3-5, 0-0 Away) | - | | | | |
| December 23, 2027 | FAIRFIELD STAGS (3-4, 1-4 Away) Gulf Coast Showcase | - | | | | |
| December 26, 2027 | RUTGERS SCARLET KNIGHTS (5-4, 0-0, 0-1 Away)* | - | | | | |
| December 28, 2027 | @ Indiana Hoosiers (4-4, 0-0, 3-1 Home)* | - | | | | |
| January 2, 2028 | @ Oregon Ducks (4-5, 0-0, 3-3 Home)* | - | | | | |
| January 4, 2028 | WASHINGTON HUSKIES (5-3, 0-0, 0-0 Away)* | - | | | | |
| January 9, 2028 | @ Southern California Trojans (5-3, 0-0, 5-3 Home)* | - | | | | |
| January 11, 2028 | MINNESOTA GOLDEN GOPHERS (7-3, 0-0, 0-2 Away)* | - | | | | |
| January 16, 2028 | @ Iowa Hawkeyes (3-5, 0-0, 3-2 Home)* | - | | | | |
| January 18, 2028 | NEBRASKA CORNHUSKERS (4-4, 0-0, 0-1 Away)* | - | | | | |
| January 23, 2028 | @ UCLA Bruins (8-2, 0-0, 5-1 Home)* | - | | | | |
| January 25, 2028 | @ Illinois Fighting Illini (6-3, 0-0, 6-1 Home)* | - | | | | |
| January 30, 2028 | WISCONSIN BADGERS (6-2, 0-0, 1-1 Away)* | - | | | | |
| February 1, 2028 | @ Michigan Wolverines (10-0, 0-0, 7-0 Home)* | - | | | | |
| February 6, 2028 | PURDUE BOILERMAKERS (6-3, 0-0, 0-0 Away)* | - | | | | |
| February 8, 2028 | MARYLAND TERRAPINS (6-2, 0-0, 0-1 Away)* | - | | | | |
| February 13, 2028 | @ Penn State Nittany Lions (3-4, 0-0, 3-3 Home)* | - | | | | |
| February 15, 2028 | @ Ohio State Buckeyes (6-3, 0-0, 4-0 Home)* | - | | | | |
| February 20, 2028 | NORTHWESTERN WILDCATS (5-3, 0-0, 0-1 Away)* | - | | | | |
| February 22, 2028 | IOWA HAWKEYES (3-5, 0-0, 0-2 Away)* | - | | | | |
| February 27, 2028 | INDIANA HOOSIERS (4-4, 0-0, 1-2 Away)* | - | | | | |
| March 1, 2028 | @ Nebraska Cornhuskers (4-4, 0-0, 4-2 Home)* | - | | | | |
