| November 14, 2027 | CHARLESTON COUGARS NIT Season Tip-Off | W 72-50 | 1-0 | B. Holbrook 15 | C. Austin 4 | A. Richmond 12 |
| November 16, 2027 | #15 GONZAGA BULLDOGS NIT Season Tip-Off | L 69-75 | 1-1 | B. Holbrook 18 | C. Austin 4 | A. Richmond 12 |
| November 22, 2027 | @ #9 West Virginia Mountaineers | L 66-75 | 1-2 | E. Hayes 15 | B. Holbrook 3 | A. Richmond 7 |
| November 25, 2027 | WYOMING COWBOYS | W 80-64 | 2-2 | A. Richmond 17 | B. Holbrook 4 | A. Richmond 17 |
| November 29, 2027 | HARVARD CRIMSON | W 98-68 | 3-2 | A. Richmond 20 | B. Holbrook 6 | A. Richmond 13 |
| December 2, 2027 | UTAH UTES | W 72-66 | 4-2 | K. Blackman 13 | B. Holbrook 4 | T. Hahn 5 |
| December 6, 2027 | HOFSTRA PRIDE | W 81-56 | 5-2 | A. Richmond 18 | B. Holbrook 6 | B. Holbrook 7 |
| December 13, 2027 | CONNECTICUT HUSKIES | W 88-82 OT | 6-2 | B. Holbrook 24 | B. Holbrook 5 | T. Hahn 9 |
| December 20, 2027 | #19 IOWA STATE CYCLONES | W 70-64 | 7-2 | A. Richmond 17 | B. Holbrook 3 | T. Hahn 15 |
| December 23, 2027 | @ Houston Cougars | W 71-65 | 8-2 | E. Hayes 22 | R. Cornette 4 | A. Richmond 11 |
| December 26, 2027 | @ Northwestern Wildcats* | W 75-57 | 9-2 | B. Holbrook 15 | K. Blackman 5 | A. Richmond 10 |
| December 28, 2027 | @ Southern California Trojans* | L 85-87 | 9-3 | E. Hayes 27 | B. Holbrook 9 | A. Richmond 13 |
| January 2, 2028 | #25 UCLA BRUINS* | W 75-69 | 10-3 | A. Richmond 18 | A. Richmond 3 | A. Richmond 10 |
| January 4, 2028 | INDIANA HOOSIERS* | W 84-70 | 11-3 | E. Hayes 23 | K. Blackman 3 | K. Blackman 9 |
| January 9, 2028 | MINNESOTA GOLDEN GOPHERS* | W 96-70 | 12-3 | A. Richmond 26 | B. Holbrook 7 | A. Richmond 15 |
| January 11, 2028 | RUTGERS SCARLET KNIGHTS* | W 81-64 | 13-3 | M. Underwood 16 | B. Holbrook 5 | M. Underwood 9 |
| January 16, 2028 | @ Purdue Boilermakers* | L 78-82 | 13-4 | A. Richmond 14 | C. Austin 6 | A. Richmond 9 |
| January 18, 2028 | ILLINOIS FIGHTING ILLINI* | W 73-63 | 14-4 | E. Hayes 19 | B. Holbrook 3 | B. Holbrook 8 |
| January 23, 2028 | IOWA HAWKEYES* | W 80-63 | 15-4 | E. Hayes 23 | B. Holbrook 7 | A. Richmond 9 |
| January 25, 2028 | WASHINGTON HUSKIES* | W 78-55 | 16-4 | B. Holbrook 22 | A. Richmond 4 | A. Richmond 13 |
| January 30, 2028 | @ Nebraska Cornhuskers* | W 71-59 | 17-4 | B. Holbrook 23 | K. Blackman 4 | A. Richmond 9 |
| February 1, 2028 | @ #23 Wisconsin Badgers* | L 87-95 | 17-5 | K. Blackman 18 | B. Holbrook 4 | E. Hayes 7 |
| February 6, 2028 | PENN STATE NITTANY LIONS* | W 90-67 | 18-5 | A. Richmond 16 | B. Holbrook 5 | T. Hahn 9 |
| February 8, 2028 | @ Michigan State Spartans* | L 64-68 | 18-6 | K. Blackman 14 | K. Blackman 4 | A. Richmond 8 |
| February 13, 2028 | @ #3 Michigan Wolverines* | L 61-88 | 18-7 | E. Hayes 12 | B. Holbrook 7 | B. Holbrook 7 |
| February 15, 2028 | OREGON DUCKS* | W 66-49 | 19-7 | B. Holbrook 15 | B. Holbrook 6 | A. Richmond 17 |
| February 20, 2028 | OHIO STATE BUCKEYES* | L 57-63 | 19-8 | K. Blackman 10 | T. Hahn 4 | E. Hayes 5 |
| February 22, 2028 | @ Oregon Ducks* | W 76-68 | 20-8 | B. Holbrook 17 | B. Holbrook 4 | A. Richmond 17 |
| February 27, 2028 | @ Washington Huskies* | W 73-65 | 21-8 | A. Richmond 18 | B. Holbrook 4 | A. Richmond 8 |
| March 1, 2028 | @ Indiana Hoosiers* | W 92-81 | 22-8 | E. Hayes 24 | B. Holbrook 3 | A. Richmond 8 |
| March 10, 2028 | #18 WISCONSIN BADGERS Big 10 Tournament | W 78-64 | 23-8 | A. Richmond 18 | B. Holbrook 4 | A. Richmond 13 |
| March 11, 2028 | @ Southern California Trojans Big 10 Tournament | W 88-70 | 24-8 | C. Austin 16 | B. Holbrook 7 | A. Richmond 10 |
| March 12, 2028 | @ #3 Michigan Wolverines Big 10 Tournament | W 75-68 | 25-8 | B. Holbrook 20 | C. Austin 5 | A. Richmond 11 |
