| November 15, 2027 | SO. CAROLINA UPSTATE SPARTANS | W 72-59 | 1-0 | R. Monroe 21 | J. Hancock 7 | T. King 5 |
| November 17, 2027 | NORFOLK STATE SPARTANS | W 78-59 | 2-0 | K. Cherry 19 | J. Hancock 8 | R. Monroe 6 |
| November 23, 2027 | @ Towson Tigers | L 66-89 | 2-1 | J. Hancock 9 | G. Nelson 6 | K. Cherry 6 |
| December 5, 2027 | @ Kennesaw State Owls | L 62-71 | 2-2 | J. Hancock 17 | R. Monroe 4 | T. King 4 |
| December 10, 2027 | PENNSYLVANIA QUAKERS | L 79-87 | 2-3 | D. Micheals 14 | D. Micheals 3 | R. Monroe 5 |
| December 14, 2027 | CHARLESTON COUGARS | L 76-81 | 2-4 | T. King 17 | J. Hancock 6 | R. Monroe 8 |
| December 15, 2027 | @ South Carolina State Bulldogs | W 92-75 | 3-4 | D. Micheals 20 | J. Hancock 10 | R. Monroe 9 |
| December 19, 2027 | @ Fairfield Stags | L 89-94 | 3-5 | K. Cherry 15 | D. Micheals 5 | R. Hathaway 8 |
| December 24, 2027 | @ San Jose State Spartans | L 67-83 | 3-6 | D. Micheals 14 | J. Hancock 3 | K. Cherry 9 |
| December 26, 2027 | SAINT PETERS PEACOCKS | W 81-71 | 4-6 | M. Meeking 19 | K. Cherry 5 | T. King 11 |
| December 29, 2027 | AUSTIN PEAY GOVERNORS | L 59-70 | 4-7 | M. Bailey 13 | J. Hancock 3 | J. Hancock 4 |
| January 2, 2028 | WESTERN ILLINOIS LEATHERNECKS* | W 74-59 | 5-7 | J. Hancock 16 | M. Meeking 5 | R. Monroe 6 |
| January 6, 2028 | @ Eastern Illinois Panthers* | L 81-82 | 5-8 | K. Cherry 21 | R. Hathaway 5 | R. Monroe 6 |
| January 9, 2028 | LINDENWOOD LIONS* | L 89-93 | 5-9 | D. Micheals 20 | J. Hancock 6 | R. Monroe 5 |
| January 13, 2028 | @ Morehead State Eagles* | L 55-73 | 5-10 | D. Micheals 15 | J. Hancock 3 | R. Monroe 6 |
| January 16, 2028 | TENNESSEE STATE TIGERS* | W 89-73 | 6-10 | R. Monroe 19 | K. Cherry 6 | R. Monroe 7 |
| January 18, 2028 | EASTERN ILLINOIS PANTHERS* | W 86-79 | 7-10 | R. Monroe 21 | J. Hancock 5 | K. Cherry 13 |
| January 23, 2028 | @ SIU Edwardsville Cougars* | L 81-96 | 7-11 | D. Micheals 15 | J. Hancock 3 | R. Monroe 6 |
| January 25, 2028 | SE MISSOURI STATE REDHAWKS* | L 62-69 | 7-12 | K. Cherry 13 | J. Hancock 4 | K. Cherry 10 |
| January 30, 2028 | @ Western Illinois Leathernecks* | W 71-55 | 8-12 | K. Cherry 17 | J. Hancock 5 | K. Cherry 5 |
| February 1, 2028 | SOUTHERN INDIANA SCREAMING EAGLES* | W 88-62 | 9-12 | K. Cherry 17 | J. Hancock 4 | K. Cherry 9 |
| February 3, 2028 | @ Tennessee Tech Golden Eagles* | L 71-78 | 9-13 | D. Micheals 27 | J. Hancock 10 | D. Micheals 8 |
| February 10, 2028 | @ Tennessee-Martin Skyhawks* | L 71-75 | 9-14 | K. Cherry 20 | D. Micheals 3 | K. Cherry 6 |
| February 13, 2028 | @ Tennessee State Tigers* | L 83-95 | 9-15 | K. Cherry 22 | J. Hancock 9 | R. Monroe 6 |
| February 15, 2028 | MOREHEAD STATE EAGLES* | W 85-71 | 10-15 | R. Monroe 22 | T. King 5 | K. Cherry 11 |
| February 17, 2028 | @ Southern Indiana Screaming Eagles* | L 79-91 | 10-16 | R. Monroe 15 | G. Nelson 4 | R. Monroe 10 |
| February 20, 2028 | TENNESSEE TECH GOLDEN EAGLES* | W 74-67 | 11-16 | D. Micheals 17 | J. Hancock 6 | K. Cherry 8 |
| February 27, 2028 | @ Lindenwood Lions* | L 65-85 | 11-17 | R. Monroe 14 | D. Micheals 4 | R. Monroe 8 |
| March 1, 2028 | SIU EDWARDSVILLE COUGARS* | W 86-64 | 12-17 | D. Micheals 18 | J. Hancock 6 | R. Monroe 8 |
| March 5, 2028 | @ Tennessee Tech Golden Eagles (12-17, 8-5 Home) OVC Tournament | - | | | | |
