| November 14, 2027 | @ Vanderbilt Commodores | L 48-69 | 0-1 | T. Reed 13 | A. Collins 4 | J. Clancy 10 |
| November 19, 2027 | @ Florida State Seminoles | W 69-58 | 1-1 | I. Riley 14 | A. Collins 6 | I. Riley 10 |
| November 21, 2027 | MERCYHURST LAKERS | W 89-71 | 2-1 | J. Wells 25 | I. Riley 5 | J. Clancy 9 |
| November 26, 2027 | @ New Mexico Lobos | L 59-81 | 2-2 | J. Clancy 12 | J. Gill 4 | I. Riley 8 |
| November 30, 2027 | @ Providence Friars | W 88-80 | 3-2 | J. Gill 18 | A. Collins 5 | J. Gill 13 |
| December 2, 2027 | @ Akron Zips | L 85-92 | 3-3 | J. Wells 22 | A. Collins 6 | I. Riley 7 |
| December 5, 2027 | @ Mississippi State Bulldogs | L 65-76 | 3-4 | J. Clancy 16 | J. Gill 6 | J. Clancy 12 |
| December 8, 2027 | DELAWARE FIGHTIN' BLUE HENS | W 85-66 | 4-4 | J. Wells 21 | A. Collins 4 | T. Hargrove 8 |
| December 12, 2027 | TEXAS-EL PASO MINERS | W 68-55 | 5-4 | J. Clancy 17 | A. Collins 6 | J. Clancy 9 |
| December 15, 2027 | @ Austin Peay Governors | L 75-96 | 5-5 | I. Riley 21 | A. Collins 4 | J. Gill 5 |
| December 20, 2027 | @ Presbyterian Blue Hose | L 76-86 | 5-6 | A. Collins 18 | A. Collins 3 | I. Riley 8 |
| December 27, 2027 | @ Ball State Cardinals | W 83-73 | 6-6 | J. Gill 16 | T. Reed 4 | I. Riley 11 |
| January 2, 2028 | @ Holy Cross Crusaders* | W 77-70 | 7-6 | I. Riley 15 | I. Riley 4 | J. Wells 7 |
| January 5, 2028 | NAVY MIDSHIPMEN* | L 83-90 | 7-7 | M. Babcock 16 | A. Collins 5 | M. Babcock 8 |
| January 9, 2028 | @ Boston University Terriers* | W 74-61 | 8-7 | J. Gill 19 | A. Collins 6 | I. Riley 7 |
| January 12, 2028 | AMERICAN EAGLES* | W 73-71 | 9-7 | I. Riley 20 | A. Collins 4 | I. Riley 7 |
| January 16, 2028 | @ Army Black Knights* | L 79-86 | 9-8 | J. Wells 19 | J. Gill 5 | J. Clancy 7 |
| January 19, 2028 | LAFAYETTE LEOPARDS* | W 85-78 | 10-8 | A. Collins 16 | J. Wells 6 | T. Hargrove 7 |
| January 23, 2028 | @ Loyola (MD) Greyhounds* | L 78-85 | 10-9 | J. Wells 16 | A. Collins 7 | J. Clancy 9 |
| January 26, 2028 | BUCKNELL BISON* | W 92-70 | 11-9 | J. Gill 21 | A. Collins 6 | J. Gill 7 |
| January 30, 2028 | @ Colgate Raiders* | L 75-85 | 11-10 | J. Gill 15 | A. Collins 5 | J. Clancy 7 |
| February 2, 2028 | HOLY CROSS CRUSADERS* | W 83-64 | 12-10 | J. Gill 24 | A. Collins 7 | J. Gill 9 |
| February 6, 2028 | @ Navy Midshipmen* | L 91-102 | 12-11 | A. Collins 18 | A. Collins 8 | I. Riley 5 |
| February 9, 2028 | BOSTON UNIVERSITY TERRIERS* | W 90-83 | 13-11 | J. Gill 23 | A. Collins 6 | J. Clancy 8 |
| February 13, 2028 | @ American Eagles* | W 93-74 | 14-11 | A. Collins 19 | A. Collins 6 | I. Riley 8 |
| February 16, 2028 | ARMY BLACK KNIGHTS* | L 89-100 | 14-12 | A. Collins 21 | T. Reed 8 | T. Hargrove 8 |
| February 20, 2028 | @ Lafayette Leopards* | W 91-82 | 15-12 | J. Wells 21 | T. Reed 10 | I. Riley 10 |
| February 23, 2028 | LOYOLA (MD) GREYHOUNDS* | W 89-72 | 16-12 | J. Wells 21 | T. Reed 10 | I. Riley 10 |
| February 27, 2028 | @ Bucknell Bison* | L 77-82 | 16-13 | J. Clancy 16 | T. Reed 4 | J. Clancy 5 |
| March 2, 2028 | COLGATE RAIDERS* | W 79-78 | 17-13 | A. Collins 17 | E. Carter 5 | A. Collins 7 |
| March 6, 2028 | TBD Patriot Tournament | - | | | | |
