| November 14, 2027 | @ Green Bay Phoenix | L 71-82 | 0-1 | R. Caldwell 18 | C. Williams 4 | R. Caldwell 8 |
| November 17, 2027 | MURRAY STATE RACERS | L 52-73 | 0-2 | R. Caldwell 12 | L. Mandaric 4 | R. Caldwell 11 |
| November 21, 2027 | @ Minnesota Golden Gophers | L 60-80 | 0-3 | C. Holmer 11 | H. Randle 3 | C. Holmer 5 |
| November 24, 2027 | @ Colorado Buffaloes | L 54-72 | 0-4 | R. Caldwell 15 | H. Randle 3 | C. Alston 6 |
| November 28, 2027 | @ High Point Panthers | W 56-42 | 1-4 | L. Mandaric 10 | C. Holmer 5 | D. Hudson 9 |
| December 1, 2027 | @ Le Moyne Dolphins | L 65-86 | 1-5 | C. Holmer 19 | H. Randle 4 | R. Caldwell 5 |
| December 5, 2027 | LITTLE ROCK TROJANS | W 71-62 | 2-5 | R. Caldwell 17 | C. Williams 5 | R. Caldwell 10 |
| December 12, 2027 | @ Oregon State Beavers | L 69-73 | 2-6 | R. Caldwell 12 | C. Holmer 4 | C. Holmer 7 |
| December 19, 2027 | INCARNATE WORD CARDINALS | W 78-74 | 3-6 | R. Caldwell 19 | H. Randle 6 | R. Caldwell 13 |
| December 26, 2027 | TEXAS-EL PASO MINERS* | L 67-74 | 3-7 | C. Holmer 12 | L. Mandaric 4 | C. Holmer 6 |
| December 29, 2027 | FLORIDA INTERNATIONAL PANTHERS* | W 92-78 | 4-7 | R. Caldwell 24 | C. Holmer 4 | R. Caldwell 9 |
| January 2, 2028 | @ Delaware Fightin' Blue Hens* | W 81-70 | 5-7 | L. Mandaric 19 | C. Holmer 5 | C. Alston 6 |
| January 5, 2028 | @ Missouri State Bears* | L 58-77 | 5-8 | R. Caldwell 15 | H. Randle 5 | C. Alston 9 |
| January 9, 2028 | @ Liberty Flames* | L 59-68 | 5-9 | R. Caldwell 17 | R. Caldwell 3 | R. Caldwell 6 |
| January 12, 2028 | NEW MEXICO STATE AGGIES* | W 72-64 | 6-9 | H. Randle 13 | H. Randle 5 | R. Caldwell 7 |
| January 16, 2028 | MIDDLE TENNESSEE BLUE RAIDERS* | W 74-61 | 7-9 | L. Mandaric 20 | H. Randle 7 | C. Alston 8 |
| January 19, 2028 | @ Western Kentucky Hilltoppers* | L 72-87 | 7-10 | R. Caldwell 27 | C. Holmer 4 | R. Caldwell 9 |
| January 23, 2028 | @ Louisiana Tech Bulldogs* | L 54-83 | 7-11 | R. Caldwell 15 | H. Randle 3 | C. Alston 7 |
| January 26, 2028 | SAM HOUSTON STATE BEARKATS* | W 78-60 | 8-11 | H. Randle 23 | C. Holmer 5 | C. Alston 8 |
| January 30, 2028 | WESTERN KENTUCKY HILLTOPPERS* | L 68-80 | 8-12 | R. Caldwell 18 | C. Holmer 2 | R. Caldwell 10 |
| February 2, 2028 | LOUISIANA TECH BULLDOGS* | W 81-64 | 9-12 | C. Holmer 19 | C. Alston 4 | C. Alston 5 |
| February 6, 2028 | @ New Mexico State Aggies* | L 68-76 | 9-13 | C. Williams 11 | R. Caldwell 5 | R. Caldwell 4 |
| February 9, 2028 | @ Middle Tennessee Blue Raiders* | W 92-70 | 10-13 | R. Caldwell 34 | C. Holmer 5 | R. Caldwell 8 |
| February 13, 2028 | DELAWARE FIGHTIN' BLUE HENS* | L 70-82 | 10-14 | R. Caldwell 35 | C. Alston 6 | R. Caldwell 9 |
| February 16, 2028 | MISSOURI STATE BEARS* | L 58-66 | 10-15 | R. Caldwell 13 | L. Mandaric 4 | C. Alston 9 |
| February 20, 2028 | @ Texas-El Paso Miners* | W 68-59 | 11-15 | H. Randle 11 | C. Alston 3 | C. Holmer 4 |
| February 23, 2028 | @ Florida International Panthers* | L 66-79 | 11-16 | R. Caldwell 19 | H. Randle 3 | L. Mandaric 4 |
| February 27, 2028 | @ Sam Houston State Bearkats* | L 49-66 | 11-17 | H. Randle 13 | H. Randle 3 | C. Alston 6 |
| March 2, 2028 | JACKSONVILLE STATE GAMECOCKS* | L 50-63 | 11-18 | B. Ballard 11 | H. Randle 5 | C. Alston 9 |
| March 6, 2028 | @ Delaware Fightin' Blue Hens (16-13, 9-5 Home) C-USA Tournament | - | | | | |
