| November 16, 2027 | LINDENWOOD LIONS | W 92-71 | 1-0 | C. Murray 21 | D. James 7 | M. Stetson 8 |
| November 19, 2027 | TEXAS-ARLINGTON MAVERICKS | W 93-69 | 2-0 | A. Noyola 23 | D. Seymour 4 | M. Stetson 11 |
| November 23, 2027 | MIAMI (OH) REDHAWKS | W 84-68 | 3-0 | C. Murray 19 | C. Murray 7 | D. Miller 5 |
| November 30, 2027 | NORTHEASTERN HUSKIES | W 83-56 | 4-0 | D. Miller 16 | C. Murray 4 | C. Murray 8 |
| December 7, 2027 | GREEN BAY PHOENIX | W 83-74 OT | 5-0 | C. Murray 23 | C. Murray 8 | M. Stetson 11 |
| December 9, 2027 | GARDNER-WEBB RUNNIN' BULLDOGS | W 89-69 | 6-0 | C. Murray 17 | M. Hope 4 | D. Miller 5 |
| December 13, 2027 | #9 IOWA STATE CYCLONES | L 80-86 | 6-1 | C. Murray 18 | D. Miller 5 | M. Hope 7 |
| December 21, 2027 | NOTRE DAME FIGHTING IRISH | W 86-66 | 7-1 | C. Murray 19 | C. Murray 5 | M. Stetson 7 |
| December 23, 2027 | VERMONT CATAMOUNTS Gulf Coast Showcase | W 100-69 | 8-1 | D. James 23 | C. Murray 8 | M. Stetson 8 |
| December 24, 2027 | BUTLER BULLDOGS Gulf Coast Showcase | W 71-57 | 9-1 | D. James 15 | C. Murray 7 | M. Stetson 6 |
| December 25, 2027 | @ Arizona Wildcats Gulf Coast Showcase | L 62-76 | 9-2 | D. James 13 | D. James 3 | R. Ward 8 |
| December 26, 2027 | @ #9 Wisconsin Badgers* | L 54-99 | 9-3 | C. Murray 9 | C. Murray 3 | M. Stetson 9 |
| December 28, 2027 | SOUTHERN CALIFORNIA TROJANS* | W 94-85 | 10-3 | M. Hope 19 | C. Murray 7 | D. Miller 7 |
| January 2, 2028 | #15 OREGON DUCKS* | W 92-85 | 11-3 | D. James 27 | D. James 6 | L. Songaila 11 |
| January 4, 2028 | @ UCLA Bruins* | L 70-92 | 11-4 | A. Noyola 17 | C. Murray 3 | M. Stetson 8 |
| January 9, 2028 | @ Washington Huskies* | W 90-76 | 12-4 | D. James 19 | D. James 6 | M. Stetson 10 |
| January 11, 2028 | @ Northwestern Wildcats* | W 85-77 | 13-4 | A. Noyola 15 | C. Murray 5 | D. Miller 6 |
| January 16, 2028 | MARYLAND TERRAPINS* | W 77-61 | 14-4 | C. Murray 19 | D. James 8 | M. Stetson 8 |
| January 18, 2028 | @ Indiana Hoosiers* | L 55-60 | 14-5 | C. Murray 13 | C. Murray 4 | C. Murray 5 |
| January 23, 2028 | ILLINOIS FIGHTING ILLINI* | W 85-72 | 15-5 | D. James 19 | C. Murray 5 | M. Stetson 9 |
| January 25, 2028 | MINNESOTA GOLDEN GOPHERS* | W 76-65 | 16-5 | D. James 12 | D. James 6 | M. Stetson 9 |
| January 30, 2028 | @ Michigan Wolverines* | L 76-92 | 16-6 | C. Murray 32 | D. James 5 | M. Hope 8 |
| February 1, 2028 | #15 PURDUE BOILERMAKERS* | L 91-93 OT | 16-7 | D. James 22 | C. Murray 8 | M. Hope 8 |
| February 6, 2028 | RUTGERS SCARLET KNIGHTS* | W 82-70 | 17-7 | M. Stetson 20 | C. Murray 6 | M. Hope 8 |
| February 8, 2028 | PENN STATE NITTANY LIONS* | W 87-68 | 18-7 | C. Murray 15 | C. Murray 7 | M. Hope 10 |
| February 13, 2028 | @ Nebraska Cornhuskers* | L 87-95 | 18-8 | D. James 19 | C. Murray 9 | C. Murray 10 |
| February 15, 2028 | #3 MICHIGAN STATE SPARTANS* | L 76-87 | 18-9 | M. Hope 14 | D. James 6 | M. Stetson 7 |
| February 20, 2028 | @ Ohio State Buckeyes* | L 77-81 | 18-10 | C. Murray 27 | D. James 7 | M. Stetson 9 |
| February 22, 2028 | @ Penn State Nittany Lions* | L 95-103 | 18-11 | M. Stetson 19 | C. Murray 4 | M. Hope 6 |
| February 27, 2028 | @ Minnesota Golden Gophers* | L 60-74 | 18-12 | D. James 14 | C. Murray 8 | M. Stetson 8 |
| March 1, 2028 | NEBRASKA CORNHUSKERS* | W 105-82 | 19-12 | C. Murray 28 | C. Murray 11 | A. Noyola 6 |
| March 9, 2028 | TBD Big 10 Tournament | - | | | | |
